Sedentary Behaviour in Human Health and Disease

Sedentary behaviour – too much sitting as distinct from too little physical activity – is now recognised as an independent risk factor for several health outcomes and premature mortality. This is problematic as technological advancements in transportation, communications, workplaces, and domestic en...

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Tác giả chính: Daniel P. Bailey
Định dạng: Online
Ngôn ngữ:Tiếng Anh
Được phát hành: Frontiers Media SA 2021
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Truy cập trực tuyến:31957
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author Daniel P. Bailey
author_browse Daniel P. Bailey
author_facet Daniel P. Bailey
author_sort Daniel P. Bailey
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description Sedentary behaviour – too much sitting as distinct from too little physical activity – is now recognised as an independent risk factor for several health outcomes and premature mortality. This is problematic as technological advancements in transportation, communications, workplaces, and domestic entertainment has created environments that encourage engagement in sedentary behaviour. Evidence from observational epidemiology shows that prolonged sitting is associated with increased risk of disease and adverse risk marker levels including type 2 diabetes, cardiovascular diseases, some cancers, obesity, glucose tolerance, and lipids. Importantly, the associations between prolonged sitting and these health markers are independent of time spent in moderate-to-vigorous physical activity. Intriguingly, observational studies employing objective measures of sedentary time patterns using accelerometry have shown that adults who interrupt their sedentary time more frequently (breaks in sedentary time) have improved cardiometabolic profiles than those whose sedentary time is mostly uninterrupted. These beneficial associations are independent of total sedentary time and time spent in moderate-to-vigorous physical activity. In light of this evidence, experimental studies are now being conducted to identify novel mechanisms and potential causal relationships. It has been suggested that loss of muscular contractile stimulation induced through sitting impairs skeletal muscle metabolism of lipids and glucose and that the molecular processes through which these responses occur may be separate from the pathways activated when engaging in exercise. This Research Topic aims to bring together contributions from researchers to advance the sedentary behaviour research agenda and strengthen the case for reducing and breaking up sitting time in primary prevention and disease management contexts.
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spelling doab-20.500.12854ir-591012024-03-31T22:45:16Z Sedentary Behaviour in Human Health and Disease Daniel P. Bailey QP1-981 Q1-390 breaks in sedentary time energy expenditure sedentary behavior sitting physical activity thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFG Physiology Sedentary behaviour – too much sitting as distinct from too little physical activity – is now recognised as an independent risk factor for several health outcomes and premature mortality. This is problematic as technological advancements in transportation, communications, workplaces, and domestic entertainment has created environments that encourage engagement in sedentary behaviour. Evidence from observational epidemiology shows that prolonged sitting is associated with increased risk of disease and adverse risk marker levels including type 2 diabetes, cardiovascular diseases, some cancers, obesity, glucose tolerance, and lipids. Importantly, the associations between prolonged sitting and these health markers are independent of time spent in moderate-to-vigorous physical activity. Intriguingly, observational studies employing objective measures of sedentary time patterns using accelerometry have shown that adults who interrupt their sedentary time more frequently (breaks in sedentary time) have improved cardiometabolic profiles than those whose sedentary time is mostly uninterrupted. These beneficial associations are independent of total sedentary time and time spent in moderate-to-vigorous physical activity. In light of this evidence, experimental studies are now being conducted to identify novel mechanisms and potential causal relationships. It has been suggested that loss of muscular contractile stimulation induced through sitting impairs skeletal muscle metabolism of lipids and glucose and that the molecular processes through which these responses occur may be separate from the pathways activated when engaging in exercise. This Research Topic aims to bring together contributions from researchers to advance the sedentary behaviour research agenda and strengthen the case for reducing and breaking up sitting time in primary prevention and disease management contexts. 2021-02-12T03:11:43Z 2021-02-12T03:11:43Z 2019-01-23 14:53:42 2018 book 31957 16648714 9782889455478 https://directory.doabooks.org/handle/20.500.12854/59101 eng Frontiers Research Topics image/jpeg Attribution 4.0 International https://www.frontiersin.org/research-topics/4084/sedentary-behaviour-in-human-health-and-disease Frontiers Media SA 10.3389/978-2-88945-547-8 10.3389/978-2-88945-547-8 bf5ce210-e72e-4860-ba9b-c305640ff3ae 9782889455478 74 open access
spellingShingle QP1-981
Q1-390
breaks in sedentary time
energy expenditure
sedentary behavior
sitting
physical activity
thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFG Physiology
Daniel P. Bailey
Sedentary Behaviour in Human Health and Disease
title Sedentary Behaviour in Human Health and Disease
title_full Sedentary Behaviour in Human Health and Disease
title_fullStr Sedentary Behaviour in Human Health and Disease
title_full_unstemmed Sedentary Behaviour in Human Health and Disease
title_short Sedentary Behaviour in Human Health and Disease
title_sort sedentary behaviour in human health and disease
topic QP1-981
Q1-390
breaks in sedentary time
energy expenditure
sedentary behavior
sitting
physical activity
thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFG Physiology
topic_facet QP1-981
Q1-390
breaks in sedentary time
energy expenditure
sedentary behavior
sitting
physical activity
thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFG Physiology
url 31957
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