Sex Hormone Receptor Signals in Human Malignancies
Sex steroids, including androgens, estrogens, and progestogens, are knownto have widespread physiological actions beyond the reproductive systemvia binding to the sex hormone receptors. Meanwhile, emerging evidence hasindicated that sex hormone receptor signals are involved in the outgrowth ofsome m...
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| Главный автор: | |
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| Формат: | Online |
| Язык: | английский |
| Опубликовано: |
MDPI - Multidisciplinary Digital Publishing Institute
2021
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| Предметы: | |
| Online-ссылка: | 42547 |
| Метки: |
Нет меток, Требуется 1-ая метка записи!
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| _version_ | 1869514935579443200 |
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| author | Miyamoto, Hiroshi |
| author_browse | Miyamoto, Hiroshi |
| author_facet | Miyamoto, Hiroshi |
| author_sort | Miyamoto, Hiroshi |
| collection | Directory of Open Access Books |
| description | Sex steroids, including androgens, estrogens, and progestogens, are knownto have widespread physiological actions beyond the reproductive systemvia binding to the sex hormone receptors. Meanwhile, emerging evidence hasindicated that sex hormone receptor signals are involved in the outgrowth ofsome malignancies, such as prostate and breast carcinomas, as well as othersthat have not traditionally been considered as endocrine-related neoplasms. ThisSpecial Issue “Sex Hormone Receptor Signals in Human Malignancies” coversvarious aspects of the potential role of sex hormone receptors and related signalsin prostate cancer, breast cancer, and other neoplastic conditions by depictingpromising findings derived from in vitro and in vivo experiments as well as theanalyses of surgical specimens. The current observations described may thusprovide a unique insight into novel or known functions of sex hormone receptorsand related molecules. |
| format | Online |
| id | doab-20.500.12854ir-59280 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-592802024-04-05T12:31:49Z Sex Hormone Receptor Signals in Human Malignancies Miyamoto, Hiroshi QH301-705.5 Q1-390 FOXA1 COBRA1 n/a estrogen progesterone receptor negative mutational profiling heterogeneous nuclear ribonucleoprotein K estrogen receptor alpha salivary gland tumors castration-resistant prostate cancer ELK1 fibroblasts androgen receptor melanocytes drug screening and proteomics PI3K pathway NELFB therapeutic targets immunohistochemistry androgen deprivation therapy ovarian cancer estrogen receptor epidermal growth factor receptor ethinylestradiol melanoma breast cancer keratinocytes G-protein coupled estrogen receptor prognosis levonorgestrel ultraviolet radiation sex hormone receptors upper urinary tract urothelial carcinoma CRPC nuclear factor erythroid 2-related factor 2 TP53 thema EDItEUR::P Mathematics and Science::PS Biology, life sciences Sex steroids, including androgens, estrogens, and progestogens, are knownto have widespread physiological actions beyond the reproductive systemvia binding to the sex hormone receptors. Meanwhile, emerging evidence hasindicated that sex hormone receptor signals are involved in the outgrowth ofsome malignancies, such as prostate and breast carcinomas, as well as othersthat have not traditionally been considered as endocrine-related neoplasms. ThisSpecial Issue “Sex Hormone Receptor Signals in Human Malignancies” coversvarious aspects of the potential role of sex hormone receptors and related signalsin prostate cancer, breast cancer, and other neoplastic conditions by depictingpromising findings derived from in vitro and in vivo experiments as well as theanalyses of surgical specimens. The current observations described may thusprovide a unique insight into novel or known functions of sex hormone receptorsand related molecules. 2021-02-12T03:27:27Z 2021-02-12T03:27:27Z 2019-12-09 11:49:15 2019 book 42547 9783039211739 9783039211746 https://directory.doabooks.org/handle/20.500.12854/59280 eng application/octet-stream Attribution-NonCommercial-NoDerivatives 4.0 International https://mdpi.com/books/pdfview/book/1601 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-03921-174-6 10.3390/books978-3-03921-174-6 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783039211739 9783039211746 152 open access |
| spellingShingle | QH301-705.5 Q1-390 FOXA1 COBRA1 n/a estrogen progesterone receptor negative mutational profiling heterogeneous nuclear ribonucleoprotein K estrogen receptor alpha salivary gland tumors castration-resistant prostate cancer ELK1 fibroblasts androgen receptor melanocytes drug screening and proteomics PI3K pathway NELFB therapeutic targets immunohistochemistry androgen deprivation therapy ovarian cancer estrogen receptor epidermal growth factor receptor ethinylestradiol melanoma breast cancer keratinocytes G-protein coupled estrogen receptor prognosis levonorgestrel ultraviolet radiation sex hormone receptors upper urinary tract urothelial carcinoma CRPC nuclear factor erythroid 2-related factor 2 TP53 thema EDItEUR::P Mathematics and Science::PS Biology, life sciences Miyamoto, Hiroshi Sex Hormone Receptor Signals in Human Malignancies |
| title | Sex Hormone Receptor Signals in Human Malignancies |
| title_full | Sex Hormone Receptor Signals in Human Malignancies |
| title_fullStr | Sex Hormone Receptor Signals in Human Malignancies |
| title_full_unstemmed | Sex Hormone Receptor Signals in Human Malignancies |
| title_short | Sex Hormone Receptor Signals in Human Malignancies |
| title_sort | sex hormone receptor signals in human malignancies |
| topic | QH301-705.5 Q1-390 FOXA1 COBRA1 n/a estrogen progesterone receptor negative mutational profiling heterogeneous nuclear ribonucleoprotein K estrogen receptor alpha salivary gland tumors castration-resistant prostate cancer ELK1 fibroblasts androgen receptor melanocytes drug screening and proteomics PI3K pathway NELFB therapeutic targets immunohistochemistry androgen deprivation therapy ovarian cancer estrogen receptor epidermal growth factor receptor ethinylestradiol melanoma breast cancer keratinocytes G-protein coupled estrogen receptor prognosis levonorgestrel ultraviolet radiation sex hormone receptors upper urinary tract urothelial carcinoma CRPC nuclear factor erythroid 2-related factor 2 TP53 thema EDItEUR::P Mathematics and Science::PS Biology, life sciences |
| topic_facet | QH301-705.5 Q1-390 FOXA1 COBRA1 n/a estrogen progesterone receptor negative mutational profiling heterogeneous nuclear ribonucleoprotein K estrogen receptor alpha salivary gland tumors castration-resistant prostate cancer ELK1 fibroblasts androgen receptor melanocytes drug screening and proteomics PI3K pathway NELFB therapeutic targets immunohistochemistry androgen deprivation therapy ovarian cancer estrogen receptor epidermal growth factor receptor ethinylestradiol melanoma breast cancer keratinocytes G-protein coupled estrogen receptor prognosis levonorgestrel ultraviolet radiation sex hormone receptors upper urinary tract urothelial carcinoma CRPC nuclear factor erythroid 2-related factor 2 TP53 thema EDItEUR::P Mathematics and Science::PS Biology, life sciences |
| url | 42547 |
| work_keys_str_mv | AT miyamotohiroshi sexhormonereceptorsignalsinhumanmalignancies |