Signalling Pathways in Embryonic Development
The formation of a complex multicellular organism from a single cell is one of the most amazing processes of biology. Embryonic development is characterised by the careful regulation of cellular behaviours such that cells proliferate, migrate, differentiate and form tissues at the correct place and...
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| मुख्य लेखकों: | , , |
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| स्वरूप: | Online |
| भाषा: | अंग्रेज़ी |
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Frontiers Media SA
2021
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| विषय: | |
| ऑनलाइन पहुंच: | 25646 |
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कोई टैग नहीं, इस रिकॉर्ड को टैग करने वाले पहले व्यक्ति बनें!
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| _version_ | 1869516279999627264 |
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| author | Andrea E. Munsterberg Sigmar Stricker Juan J. Sanz-Ezquerro |
| author_browse | Andrea E. Munsterberg Juan J. Sanz-Ezquerro Sigmar Stricker |
| author_facet | Andrea E. Munsterberg Sigmar Stricker Juan J. Sanz-Ezquerro |
| author_sort | Andrea E. Munsterberg |
| collection | Directory of Open Access Books |
| description | The formation of a complex multicellular organism from a single cell is one of the most amazing processes of biology. Embryonic development is characterised by the careful regulation of cellular behaviours such that cells proliferate, migrate, differentiate and form tissues at the correct place and time. These processes are genetically controlled and depend both on the history of cells, their lineage, and on the activities of signalling pathways, which coordinate the cell interactions leading to organogenesis. The aim of the Frontiers research topic “Signalling pathways in embryonic development” has been to provide a forum for experts in cell and developmental biology to share recent advances in the field of signalling during embryonic development. Sixteen articles in a variety of formats are united in this Topic, offering a valuable collection for researchers looking for an update in the knowledge of signalling pathways operating during embryogenesis. The works, focused mainly on vertebrates, explore different aspects of this theme from cell communication to organ formation and have implications for areas as distant as evolution or pathology. Understanding developmental signalling pathways is important for several reasons. It gives us information about basic mechanisms of cell function and interactions needed for morphogenesis and organogenesis. It uncovers the basis of congenital malformations, since errors at any step of cell signalling during development are a major cause of defects. This fundamental insight gives us clues to understand the mechanisms operating in evolution that explain diversity in form and function. And finally, it allows the identification of possible causes of disease in the adult organism (such as cancer or degenerative diseases) pinpointing possible targets for therapeutic approaches. |
| format | Online |
| id | doab-20.500.12854ir-59364 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | Frontiers Media SA |
| publisherStr | Frontiers Media SA |
| record_format | ojs |
| spelling | doab-20.500.12854ir-593642024-04-05T12:31:55Z Signalling Pathways in Embryonic Development Andrea E. Munsterberg Sigmar Stricker Juan J. Sanz-Ezquerro QH301-705.5 Q1-390 development Shh Fgf Notch embryo Signalling organogenesis Wnt thema EDItEUR::P Mathematics and Science::PS Biology, life sciences The formation of a complex multicellular organism from a single cell is one of the most amazing processes of biology. Embryonic development is characterised by the careful regulation of cellular behaviours such that cells proliferate, migrate, differentiate and form tissues at the correct place and time. These processes are genetically controlled and depend both on the history of cells, their lineage, and on the activities of signalling pathways, which coordinate the cell interactions leading to organogenesis. The aim of the Frontiers research topic “Signalling pathways in embryonic development” has been to provide a forum for experts in cell and developmental biology to share recent advances in the field of signalling during embryonic development. Sixteen articles in a variety of formats are united in this Topic, offering a valuable collection for researchers looking for an update in the knowledge of signalling pathways operating during embryogenesis. The works, focused mainly on vertebrates, explore different aspects of this theme from cell communication to organ formation and have implications for areas as distant as evolution or pathology. Understanding developmental signalling pathways is important for several reasons. It gives us information about basic mechanisms of cell function and interactions needed for morphogenesis and organogenesis. It uncovers the basis of congenital malformations, since errors at any step of cell signalling during development are a major cause of defects. This fundamental insight gives us clues to understand the mechanisms operating in evolution that explain diversity in form and function. And finally, it allows the identification of possible causes of disease in the adult organism (such as cancer or degenerative diseases) pinpointing possible targets for therapeutic approaches. 2021-02-12T03:35:14Z 2021-02-12T03:35:14Z 2018-02-27 16:16:45 2017 book 25646 16648714 9782889453467 https://directory.doabooks.org/handle/20.500.12854/59364 eng Frontiers Research Topics image/jpeg Attribution 4.0 International https://www.frontiersin.org/books/Signalling_Pathways_in_Embryonic_Development/1399 https://www.frontiersin.org/research-topics/4712/signalling-pathways-in-embryonic-development Frontiers Media SA 10.3389/978-2-88945-346-7 10.3389/978-2-88945-346-7 bf5ce210-e72e-4860-ba9b-c305640ff3ae 9782889453467 177 open access |
| spellingShingle | QH301-705.5 Q1-390 development Shh Fgf Notch embryo Signalling organogenesis Wnt thema EDItEUR::P Mathematics and Science::PS Biology, life sciences Andrea E. Munsterberg Sigmar Stricker Juan J. Sanz-Ezquerro Signalling Pathways in Embryonic Development |
| title | Signalling Pathways in Embryonic Development |
| title_full | Signalling Pathways in Embryonic Development |
| title_fullStr | Signalling Pathways in Embryonic Development |
| title_full_unstemmed | Signalling Pathways in Embryonic Development |
| title_short | Signalling Pathways in Embryonic Development |
| title_sort | signalling pathways in embryonic development |
| topic | QH301-705.5 Q1-390 development Shh Fgf Notch embryo Signalling organogenesis Wnt thema EDItEUR::P Mathematics and Science::PS Biology, life sciences |
| topic_facet | QH301-705.5 Q1-390 development Shh Fgf Notch embryo Signalling organogenesis Wnt thema EDItEUR::P Mathematics and Science::PS Biology, life sciences |
| url | 25646 |
| work_keys_str_mv | AT andreaemunsterberg signallingpathwaysinembryonicdevelopment AT sigmarstricker signallingpathwaysinembryonicdevelopment AT juanjsanzezquerro signallingpathwaysinembryonicdevelopment |