Synthetic biology applications in industrial microbiology

Exponentially increasing information on biological organisms coupled with increasing computational power in the past decade have broadened the perspective of fundamental biological research, bringing about considerable promise and unprecedented potential for practical applications in biotechnology....

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Main Authors: David Nielsen, Weiwen Zhang
Format: Online
Sprog:engelsk
Udgivet: Frontiers Media SA 2021
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Online adgang:18672
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author David Nielsen
Weiwen Zhang
author_browse David Nielsen
Weiwen Zhang
author_facet David Nielsen
Weiwen Zhang
author_sort David Nielsen
collection Directory of Open Access Books
description Exponentially increasing information on biological organisms coupled with increasing computational power in the past decade have broadened the perspective of fundamental biological research, bringing about considerable promise and unprecedented potential for practical applications in biotechnology. As one emergent discipline, synthetic biology aims to design and engineer novel biologically-based parts, devices, and systems, in addition to redesigning existing, natural biological systems. Although previously relegated to demonstration studies, more recent research in synthetic biology has focused on the rational engineering of industrial microorganisms with the potential to address many of society’s critical challenges. Within the realm of industrial microbiology, progress in the field of synthetic biology has enabled the development of, for example, new biosynthetic pathways for the production of renewable fuels and chemicals, programmable logic controls to regulate and optimize cell function, and robust microbes for the destruction of harmful environmental contaminants. Some of the exciting examples included producing anti-malarial drug, anti- cancer taxol precursor and various biofuel molecules in E. coli and yeast. In addition, these researches have also greatly enhanced our understanding of the cellular machinery and its regulation in some of the industry important microbes, laying an important foundation for further design and engineering of biological function for even greater application. For these reasons, we present here a collection of articles from the leading edge of the field of synthetic biology, with a specific focus on the development in industrial microorganisms. It is the intent of this collection to reach a wide audience whose interests and expertise spans from development of novel synthetic biology methodologies and theories (both experimental and computational) to practical applications seeking to address issues facing the world today.
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spelling doab-20.500.12854ir-604132024-03-30T02:52:50Z Synthetic biology applications in industrial microbiology David Nielsen Weiwen Zhang GE1-350 TP248.13-248.65 TA1-2040 QR1-502 Q1-390 Industrial Microbiology Biotechnology Synthetic Biology microbial systems chemicals thema EDItEUR::K Economics, Finance, Business and Management::KC Economics::KCV Economics of specific sectors::KCVG Environmental economics Exponentially increasing information on biological organisms coupled with increasing computational power in the past decade have broadened the perspective of fundamental biological research, bringing about considerable promise and unprecedented potential for practical applications in biotechnology. As one emergent discipline, synthetic biology aims to design and engineer novel biologically-based parts, devices, and systems, in addition to redesigning existing, natural biological systems. Although previously relegated to demonstration studies, more recent research in synthetic biology has focused on the rational engineering of industrial microorganisms with the potential to address many of society’s critical challenges. Within the realm of industrial microbiology, progress in the field of synthetic biology has enabled the development of, for example, new biosynthetic pathways for the production of renewable fuels and chemicals, programmable logic controls to regulate and optimize cell function, and robust microbes for the destruction of harmful environmental contaminants. Some of the exciting examples included producing anti-malarial drug, anti- cancer taxol precursor and various biofuel molecules in E. coli and yeast. In addition, these researches have also greatly enhanced our understanding of the cellular machinery and its regulation in some of the industry important microbes, laying an important foundation for further design and engineering of biological function for even greater application. For these reasons, we present here a collection of articles from the leading edge of the field of synthetic biology, with a specific focus on the development in industrial microorganisms. It is the intent of this collection to reach a wide audience whose interests and expertise spans from development of novel synthetic biology methodologies and theories (both experimental and computational) to practical applications seeking to address issues facing the world today. 2021-02-12T05:07:06Z 2021-02-12T05:07:06Z 2016-03-10 08:14:32 2014 book 18672 16648714 9782889193424 https://directory.doabooks.org/handle/20.500.12854/60413 eng Frontiers Research Topics image/jpeg Attribution 4.0 International http://www.frontiersin.org/books/Synthetic_biology_applications_in_industrial_microbiology/384 http://journal.frontiersin.org/researchtopic/455/synthetic-biology-applications-in-industrial-microbiology Frontiers Media SA 10.3389/978-2-88919-342-4 10.3389/978-2-88919-342-4 bf5ce210-e72e-4860-ba9b-c305640ff3ae 9782889193424 129 open access
spellingShingle GE1-350
TP248.13-248.65
TA1-2040
QR1-502
Q1-390
Industrial Microbiology
Biotechnology
Synthetic Biology
microbial systems
chemicals
thema EDItEUR::K Economics, Finance, Business and Management::KC Economics::KCV Economics of specific sectors::KCVG Environmental economics
David Nielsen
Weiwen Zhang
Synthetic biology applications in industrial microbiology
title Synthetic biology applications in industrial microbiology
title_full Synthetic biology applications in industrial microbiology
title_fullStr Synthetic biology applications in industrial microbiology
title_full_unstemmed Synthetic biology applications in industrial microbiology
title_short Synthetic biology applications in industrial microbiology
title_sort synthetic biology applications in industrial microbiology
topic GE1-350
TP248.13-248.65
TA1-2040
QR1-502
Q1-390
Industrial Microbiology
Biotechnology
Synthetic Biology
microbial systems
chemicals
thema EDItEUR::K Economics, Finance, Business and Management::KC Economics::KCV Economics of specific sectors::KCVG Environmental economics
topic_facet GE1-350
TP248.13-248.65
TA1-2040
QR1-502
Q1-390
Industrial Microbiology
Biotechnology
Synthetic Biology
microbial systems
chemicals
thema EDItEUR::K Economics, Finance, Business and Management::KC Economics::KCV Economics of specific sectors::KCVG Environmental economics
url 18672
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