Systems Analytics and Integration of Big Omics Data

A “genotype"" is essentially an organism's full hereditary information which is obtained from its parents. A ""phenotype"" is an organism's actual observed physical and behavioral properties. These may include traits such as morphology, size, height, eye color, metabolism, etc. One of the pressing c...

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Detalles Bibliográficos
Autor Principal:	Hardiman, Gary
Formato:	Online
Idioma:	inglés
Publicado:	MDPI - Multidisciplinary Digital Publishing Institute 2021
Subjects:	R5-920 RM1-950 precision medicine informatics n/a drug sensitivity chromatin modification cell lines biocuration neurodegeneration multivariate analysis artificial intelligence epigenetics missing data sequencing clinical data class imbalance integrative analytics algorithm development for network integration deep phenotype non-omics data feature selection Gene Ontology miRNA–gene expression networks omics data plot visualization Alzheimer’s disease tissue classification epidemiological data proteomic analysis genotype RNA expression indirect effect multi-omics dementia multiomics integration data integration phenomics network topology analysis challenges transcriptome enrichment analysis regulatory genomics scalability heterogeneous data systemic lupus erythematosus database microtubule-associated protein tau disease variants genomics joint modeling distance correlation annotation phenotype direct effect curse of dimensionality gene–environment interactions logic forest machine learning KEGG pathways multivariate causal mediation amyloid-beta bioinformatics pipelines support vector machine pharmacogenomics candidate genes tissue-specific expressed genes cognitive impairment causal inference thema EDItEUR::M Medicine and Nursing
Acceso en liña:	46008
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Systems Analytics and Integration of Big Omics Data

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