Tertiary Lymphoid Organs (TLOs): Powerhouses of Disease Immunity

The immune system employs TLOs to elicit highly localized and forceful responses to unresolvable peripheral tissue inflammation. Current data indicate that TLOs are protective but they may also lead to collateral tissue injury and serve as nesting places to generate autoreactive lymphocytes. A bette...

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Κύριοι συγγραφείς: Changjun Yin, Andreas J.R. Habenicht, Pasquale Maffia, Sarajo Mohanta
Μορφή: Online
Γλώσσα:Αγγλικά
Έκδοση: Frontiers Media SA 2021
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Διαθέσιμο Online:23485
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author Changjun Yin
Andreas J.R. Habenicht
Pasquale Maffia
Sarajo Mohanta
author_browse Andreas J.R. Habenicht
Changjun Yin
Pasquale Maffia
Sarajo Mohanta
author_facet Changjun Yin
Andreas J.R. Habenicht
Pasquale Maffia
Sarajo Mohanta
author_sort Changjun Yin
collection Directory of Open Access Books
description The immune system employs TLOs to elicit highly localized and forceful responses to unresolvable peripheral tissue inflammation. Current data indicate that TLOs are protective but they may also lead to collateral tissue injury and serve as nesting places to generate autoreactive lymphocytes. A better comprehension of these powerhouses of disease immunity will likely facilitate development to unprecedented and specific therapies to fight chronic inflammatory diseases.
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language eng
publishDate 2021
publishDateRange 2021
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publisherStr Frontiers Media SA
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spelling doab-20.500.12854ir-607462024-03-31T13:11:09Z Tertiary Lymphoid Organs (TLOs): Powerhouses of Disease Immunity Changjun Yin Andreas J.R. Habenicht Pasquale Maffia Sarajo Mohanta R5-920 RC581-607 Autoimmunity nonresolving peripheral tissue inflammation Autoinflammation Tertiary lymphoid organs dichotomies of immune responses disease immunity Immune Tolerance antigen thema EDItEUR::M Medicine and Nursing The immune system employs TLOs to elicit highly localized and forceful responses to unresolvable peripheral tissue inflammation. Current data indicate that TLOs are protective but they may also lead to collateral tissue injury and serve as nesting places to generate autoreactive lymphocytes. A better comprehension of these powerhouses of disease immunity will likely facilitate development to unprecedented and specific therapies to fight chronic inflammatory diseases. 2021-02-12T05:39:56Z 2021-02-12T05:39:56Z 2017-08-28 14:01:09 2017 book 23485 16648714 9782889451807 https://directory.doabooks.org/handle/20.500.12854/60746 eng Frontiers Research Topics image/jpeg Attribution 4.0 International http://www.frontiersin.org/books/Tertiary_Lymphoid_Organs_(TLOs)_Powerhouses_of_Disease_Immunity/1208#nogo http://journal.frontiersin.org/researchtopic/4362/tertiary-lymphoid-organs-tlos-powerhouses-of-disease-immunity Frontiers Media SA 10.3389/978-2-88945-180-7 10.3389/978-2-88945-180-7 bf5ce210-e72e-4860-ba9b-c305640ff3ae 9782889451807 235 open access
spellingShingle R5-920
RC581-607
Autoimmunity
nonresolving peripheral tissue inflammation
Autoinflammation
Tertiary lymphoid organs
dichotomies of immune responses
disease immunity
Immune Tolerance
antigen
thema EDItEUR::M Medicine and Nursing
Changjun Yin
Andreas J.R. Habenicht
Pasquale Maffia
Sarajo Mohanta
Tertiary Lymphoid Organs (TLOs): Powerhouses of Disease Immunity
title Tertiary Lymphoid Organs (TLOs): Powerhouses of Disease Immunity
title_full Tertiary Lymphoid Organs (TLOs): Powerhouses of Disease Immunity
title_fullStr Tertiary Lymphoid Organs (TLOs): Powerhouses of Disease Immunity
title_full_unstemmed Tertiary Lymphoid Organs (TLOs): Powerhouses of Disease Immunity
title_short Tertiary Lymphoid Organs (TLOs): Powerhouses of Disease Immunity
title_sort tertiary lymphoid organs tlos powerhouses of disease immunity
topic R5-920
RC581-607
Autoimmunity
nonresolving peripheral tissue inflammation
Autoinflammation
Tertiary lymphoid organs
dichotomies of immune responses
disease immunity
Immune Tolerance
antigen
thema EDItEUR::M Medicine and Nursing
topic_facet R5-920
RC581-607
Autoimmunity
nonresolving peripheral tissue inflammation
Autoinflammation
Tertiary lymphoid organs
dichotomies of immune responses
disease immunity
Immune Tolerance
antigen
thema EDItEUR::M Medicine and Nursing
url 23485
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AT andreasjrhabenicht tertiarylymphoidorganstlospowerhousesofdiseaseimmunity
AT pasqualemaffia tertiarylymphoidorganstlospowerhousesofdiseaseimmunity
AT sarajomohanta tertiarylymphoidorganstlospowerhousesofdiseaseimmunity