Transcriptional Regulation: Molecules, Involved Mechanisms and Misregulation

Transcriptional regulation is a critical biological process involved in the response of a cell, a tissue or an organism to a variety of intra- and extra-cellular signals. Besides, it controls the establishment and maintenance of cell identity throughout developmental and differentiation programs. Th...

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Huvudupphov: Ciccodicola, Alfredo, Casamassimi, Amelia
Materialtyp: Online
Språk:engelska
Utgiven: MDPI - Multidisciplinary Digital Publishing Institute 2021
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author Ciccodicola, Alfredo
Casamassimi, Amelia
author_browse Casamassimi, Amelia
Ciccodicola, Alfredo
author_facet Ciccodicola, Alfredo
Casamassimi, Amelia
author_sort Ciccodicola, Alfredo
collection Directory of Open Access Books
description Transcriptional regulation is a critical biological process involved in the response of a cell, a tissue or an organism to a variety of intra- and extra-cellular signals. Besides, it controls the establishment and maintenance of cell identity throughout developmental and differentiation programs. This highly complex and dynamic process is orchestrated by a huge number of molecules and protein networks and occurs through multiple temporal and functional steps. Of note, many human disorders are characterized by misregulation of global transcription since most of the signaling pathways ultimately target components of transcription machinery. This book includes a selection of papers that illustrate recent advances in our understanding of transcriptional regulation and focuses on many important topics, from cis-regulatory elements to transcription factors, chromatin regulators and non-coding RNAs, other than several transcriptome studies and computational analyses.
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publisherStr MDPI - Multidisciplinary Digital Publishing Institute
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spelling doab-20.500.12854ir-611782024-04-05T12:33:36Z Transcriptional Regulation: Molecules, Involved Mechanisms and Misregulation Ciccodicola, Alfredo Casamassimi, Amelia QH301-705.5 Q1-390 transcription factor n/a transcription self-incompatibility cytogenetics epigenetics selenocysteine tea AP-2? nonsense-mediated decay transcriptomics Akt1 promoter cell metabolism pediveliger larvae Patau Syndrome tristetraprolin (TTP) long non-coding RNA (lncRNA) pregnancy G-quadruplex glioblastoma placenta PRDM gene family circRNA-disease associations bioadhesive gene expression Crassostrea gigas transcription regulation cell differentiation RNA interference transcriptome inflammatory response FOXO1 Adiponectin liquid chromatograph-tandem mass spectrometer (LC-MS/MS) selenium selenocysteine insertion sequence inflammation selenoproteins research methods nutritional status structures and functions CRISPR/Cas9 fertilization melanin differentially expressed genes tyrosinase posttranscriptional regulation major depressive disorder human malignancies pathway CDKN1C transcription factors p57Kip2 enhancer activity mouse disorders high-throughput RNA sequencing (RNA-Seq) TCGA data analysis RNA-seq heterogeneous network insect and drug design therapeutic targets mechanisms obesity Pacific oyster Rsh regulon common pathway Pax3 somatic mutations nutrition molecular docking bioinformatics interactome long non-coding RNAs transcriptional regulation Pteria penguin (Röding Adiponectin receptors transcriptome profiling 1798) N-acyl-l-homoserine lactone ppGpp tumorigenesis sphingomonads human disease adenosine and uridine-rich elements (AREs) progress and prospects miR-25-3p acute leukemia Novosphingobium pentaromativorans US6-1 microscopy cancer molecular pathways causal inference thema EDItEUR::P Mathematics and Science::PS Biology, life sciences Transcriptional regulation is a critical biological process involved in the response of a cell, a tissue or an organism to a variety of intra- and extra-cellular signals. Besides, it controls the establishment and maintenance of cell identity throughout developmental and differentiation programs. This highly complex and dynamic process is orchestrated by a huge number of molecules and protein networks and occurs through multiple temporal and functional steps. Of note, many human disorders are characterized by misregulation of global transcription since most of the signaling pathways ultimately target components of transcription machinery. This book includes a selection of papers that illustrate recent advances in our understanding of transcriptional regulation and focuses on many important topics, from cis-regulatory elements to transcription factors, chromatin regulators and non-coding RNAs, other than several transcriptome studies and computational analyses. 2021-02-12T06:21:32Z 2021-02-12T06:21:32Z 2019-08-28 11:21:27 2019 book 35935 9783039212651 9783039212668 https://directory.doabooks.org/handle/20.500.12854/61178 eng image/jpeg Attribution-NonCommercial-NoDerivatives 4.0 International https://mdpi.com/books/pdfview/book/1459 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-03921-266-8 10.3390/books978-3-03921-266-8 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783039212651 9783039212668 356 open access
spellingShingle QH301-705.5
Q1-390
transcription factor
n/a
transcription
self-incompatibility
cytogenetics
epigenetics
selenocysteine
tea
AP-2?
nonsense-mediated decay
transcriptomics
Akt1
promoter
cell metabolism
pediveliger larvae
Patau Syndrome
tristetraprolin (TTP)
long non-coding RNA (lncRNA)
pregnancy
G-quadruplex
glioblastoma
placenta
PRDM gene family
circRNA-disease associations
bioadhesive
gene expression
Crassostrea gigas
transcription regulation
cell differentiation
RNA interference
transcriptome
inflammatory response
FOXO1
Adiponectin
liquid chromatograph-tandem mass spectrometer (LC-MS/MS)
selenium
selenocysteine insertion sequence
inflammation
selenoproteins
research methods
nutritional status
structures and functions
CRISPR/Cas9
fertilization
melanin
differentially expressed genes
tyrosinase
posttranscriptional regulation
major depressive disorder
human malignancies
pathway
CDKN1C
transcription factors
p57Kip2
enhancer activity
mouse
disorders
high-throughput RNA sequencing (RNA-Seq)
TCGA data analysis
RNA-seq
heterogeneous network
insect
and drug design
therapeutic targets
mechanisms
obesity
Pacific oyster
Rsh regulon
common pathway
Pax3
somatic mutations
nutrition
molecular docking
bioinformatics
interactome
long non-coding RNAs
transcriptional regulation
Pteria penguin (Röding
Adiponectin receptors
transcriptome profiling
1798)
N-acyl-l-homoserine lactone
ppGpp
tumorigenesis
sphingomonads
human
disease
adenosine and uridine-rich elements (AREs)
progress and prospects
miR-25-3p
acute leukemia
Novosphingobium pentaromativorans US6-1
microscopy
cancer
molecular pathways
causal inference
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
Ciccodicola, Alfredo
Casamassimi, Amelia
Transcriptional Regulation: Molecules, Involved Mechanisms and Misregulation
title Transcriptional Regulation: Molecules, Involved Mechanisms and Misregulation
title_full Transcriptional Regulation: Molecules, Involved Mechanisms and Misregulation
title_fullStr Transcriptional Regulation: Molecules, Involved Mechanisms and Misregulation
title_full_unstemmed Transcriptional Regulation: Molecules, Involved Mechanisms and Misregulation
title_short Transcriptional Regulation: Molecules, Involved Mechanisms and Misregulation
title_sort transcriptional regulation molecules involved mechanisms and misregulation
topic QH301-705.5
Q1-390
transcription factor
n/a
transcription
self-incompatibility
cytogenetics
epigenetics
selenocysteine
tea
AP-2?
nonsense-mediated decay
transcriptomics
Akt1
promoter
cell metabolism
pediveliger larvae
Patau Syndrome
tristetraprolin (TTP)
long non-coding RNA (lncRNA)
pregnancy
G-quadruplex
glioblastoma
placenta
PRDM gene family
circRNA-disease associations
bioadhesive
gene expression
Crassostrea gigas
transcription regulation
cell differentiation
RNA interference
transcriptome
inflammatory response
FOXO1
Adiponectin
liquid chromatograph-tandem mass spectrometer (LC-MS/MS)
selenium
selenocysteine insertion sequence
inflammation
selenoproteins
research methods
nutritional status
structures and functions
CRISPR/Cas9
fertilization
melanin
differentially expressed genes
tyrosinase
posttranscriptional regulation
major depressive disorder
human malignancies
pathway
CDKN1C
transcription factors
p57Kip2
enhancer activity
mouse
disorders
high-throughput RNA sequencing (RNA-Seq)
TCGA data analysis
RNA-seq
heterogeneous network
insect
and drug design
therapeutic targets
mechanisms
obesity
Pacific oyster
Rsh regulon
common pathway
Pax3
somatic mutations
nutrition
molecular docking
bioinformatics
interactome
long non-coding RNAs
transcriptional regulation
Pteria penguin (Röding
Adiponectin receptors
transcriptome profiling
1798)
N-acyl-l-homoserine lactone
ppGpp
tumorigenesis
sphingomonads
human
disease
adenosine and uridine-rich elements (AREs)
progress and prospects
miR-25-3p
acute leukemia
Novosphingobium pentaromativorans US6-1
microscopy
cancer
molecular pathways
causal inference
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
topic_facet QH301-705.5
Q1-390
transcription factor
n/a
transcription
self-incompatibility
cytogenetics
epigenetics
selenocysteine
tea
AP-2?
nonsense-mediated decay
transcriptomics
Akt1
promoter
cell metabolism
pediveliger larvae
Patau Syndrome
tristetraprolin (TTP)
long non-coding RNA (lncRNA)
pregnancy
G-quadruplex
glioblastoma
placenta
PRDM gene family
circRNA-disease associations
bioadhesive
gene expression
Crassostrea gigas
transcription regulation
cell differentiation
RNA interference
transcriptome
inflammatory response
FOXO1
Adiponectin
liquid chromatograph-tandem mass spectrometer (LC-MS/MS)
selenium
selenocysteine insertion sequence
inflammation
selenoproteins
research methods
nutritional status
structures and functions
CRISPR/Cas9
fertilization
melanin
differentially expressed genes
tyrosinase
posttranscriptional regulation
major depressive disorder
human malignancies
pathway
CDKN1C
transcription factors
p57Kip2
enhancer activity
mouse
disorders
high-throughput RNA sequencing (RNA-Seq)
TCGA data analysis
RNA-seq
heterogeneous network
insect
and drug design
therapeutic targets
mechanisms
obesity
Pacific oyster
Rsh regulon
common pathway
Pax3
somatic mutations
nutrition
molecular docking
bioinformatics
interactome
long non-coding RNAs
transcriptional regulation
Pteria penguin (Röding
Adiponectin receptors
transcriptome profiling
1798)
N-acyl-l-homoserine lactone
ppGpp
tumorigenesis
sphingomonads
human
disease
adenosine and uridine-rich elements (AREs)
progress and prospects
miR-25-3p
acute leukemia
Novosphingobium pentaromativorans US6-1
microscopy
cancer
molecular pathways
causal inference
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
url 35935
work_keys_str_mv AT ciccodicolaalfredo transcriptionalregulationmoleculesinvolvedmechanismsandmisregulation
AT casamassimiamelia transcriptionalregulationmoleculesinvolvedmechanismsandmisregulation