The truth in complexes: why unraveling ion channel multi-protein signaling nexuses is critical for understanding the function of the nervous system
In the search for simple explanations of the natural world, its complicated textures are often filed down to a smoothened surface of our liking. The impetus for this Research Topic was borne out of a need to re-ignite interest in the complex – in this case in the context of ion channels in the nervo...
保存先:
| 主要な著者: | , |
|---|---|
| フォーマット: | Online |
| 言語: | 英語 |
| 出版事項: |
Frontiers Media SA
2021
|
| 主題: | |
| オンライン･アクセス: | 18591 |
| タグ: |
タグなし, このレコードへの初めてのタグを付けませんか!
|
| _version_ | 1869515245015269376 |
|---|---|
| author | Christophe Altier Gerald W. Zamponi |
| author_browse | Christophe Altier Gerald W. Zamponi |
| author_facet | Christophe Altier Gerald W. Zamponi |
| author_sort | Christophe Altier |
| collection | Directory of Open Access Books |
| description | In the search for simple explanations of the natural world, its complicated textures are often filed down to a smoothened surface of our liking. The impetus for this Research Topic was borne out of a need to re-ignite interest in the complex – in this case in the context of ion channels in the nervous system. Ion channels are the large proteins that form regulated pores in the membranes of cells and, in the brain, are essential for the transfer, processing and storage of information. These pores full of twists and turns themselves are not just barren bridges into cells. More and more we are beginning to understand that ion channels are like bustling medieval bridges (packed with apartments and shops) rather than the more sleek modern variety – they are dynamic hubs connected with many structures facilitating associated activities. Our understanding of these networks continues to expand as our investigative tools advance. Together these articles highlight how the complexity of ion channel signaling nexuses is critical to the proper functioning of the nervous system. |
| format | Online |
| id | doab-20.500.12854ir-61379 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | Frontiers Media SA |
| publisherStr | Frontiers Media SA |
| record_format | ojs |
| spelling | doab-20.500.12854ir-613792024-04-05T12:35:29Z The truth in complexes: why unraveling ion channel multi-protein signaling nexuses is critical for understanding the function of the nervous system Christophe Altier Gerald W. Zamponi RC321-571 Q1-390 Nervous System Ion Channels Interactome cellular signaling Protein complexes thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences In the search for simple explanations of the natural world, its complicated textures are often filed down to a smoothened surface of our liking. The impetus for this Research Topic was borne out of a need to re-ignite interest in the complex – in this case in the context of ion channels in the nervous system. Ion channels are the large proteins that form regulated pores in the membranes of cells and, in the brain, are essential for the transfer, processing and storage of information. These pores full of twists and turns themselves are not just barren bridges into cells. More and more we are beginning to understand that ion channels are like bustling medieval bridges (packed with apartments and shops) rather than the more sleek modern variety – they are dynamic hubs connected with many structures facilitating associated activities. Our understanding of these networks continues to expand as our investigative tools advance. Together these articles highlight how the complexity of ion channel signaling nexuses is critical to the proper functioning of the nervous system. 2021-02-12T06:40:40Z 2021-02-12T06:40:40Z 2016-02-05 17:24:33 2015 book 18591 16648714 9782889194452 https://directory.doabooks.org/handle/20.500.12854/61379 eng Frontiers Research Topics image/jpeg Attribution 4.0 International http://www.frontiersin.org/books/The_truth_in_complexes_why_unraveling_ion_channel_multi-protein_signaling_nexuses_is_critical_for_u/494 http://journal.frontiersin.org/researchtopic/1624/the-truth-in-complexes-why-unraveling-ion-channel-multi-protein-signaling-nexuses-is-critical-for-un Frontiers Media SA 10.3389/978-2-88919-445-2 10.3389/978-2-88919-445-2 bf5ce210-e72e-4860-ba9b-c305640ff3ae 9782889194452 160 open access |
| spellingShingle | RC321-571 Q1-390 Nervous System Ion Channels Interactome cellular signaling Protein complexes thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences Christophe Altier Gerald W. Zamponi The truth in complexes: why unraveling ion channel multi-protein signaling nexuses is critical for understanding the function of the nervous system |
| title | The truth in complexes: why unraveling ion channel multi-protein signaling nexuses is critical for understanding the function of the nervous system |
| title_full | The truth in complexes: why unraveling ion channel multi-protein signaling nexuses is critical for understanding the function of the nervous system |
| title_fullStr | The truth in complexes: why unraveling ion channel multi-protein signaling nexuses is critical for understanding the function of the nervous system |
| title_full_unstemmed | The truth in complexes: why unraveling ion channel multi-protein signaling nexuses is critical for understanding the function of the nervous system |
| title_short | The truth in complexes: why unraveling ion channel multi-protein signaling nexuses is critical for understanding the function of the nervous system |
| title_sort | truth in complexes why unraveling ion channel multi protein signaling nexuses is critical for understanding the function of the nervous system |
| topic | RC321-571 Q1-390 Nervous System Ion Channels Interactome cellular signaling Protein complexes thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences |
| topic_facet | RC321-571 Q1-390 Nervous System Ion Channels Interactome cellular signaling Protein complexes thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences |
| url | 18591 |
| work_keys_str_mv | AT christophealtier thetruthincomplexeswhyunravelingionchannelmultiproteinsignalingnexusesiscriticalforunderstandingthefunctionofthenervoussystem AT geraldwzamponi thetruthincomplexeswhyunravelingionchannelmultiproteinsignalingnexusesiscriticalforunderstandingthefunctionofthenervoussystem AT christophealtier truthincomplexeswhyunravelingionchannelmultiproteinsignalingnexusesiscriticalforunderstandingthefunctionofthenervoussystem AT geraldwzamponi truthincomplexeswhyunravelingionchannelmultiproteinsignalingnexusesiscriticalforunderstandingthefunctionofthenervoussystem |