The Tumor Microenvironment of High Grade Serous Ovarian Cancer
The Special Issue on high grade serous ovarian cancer (HGSOC) and the contribution of the tumor microenviroment (TME) consists of reviews contributed by leaders in the OC field. As HGSOC metastases have a highly complex TME, there is an urgent need to better understand the TME in general, its distin...
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| Автори: | , , , |
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| Формат: | Online |
| Мова: | Англійська |
| Опубліковано: |
MDPI - Multidisciplinary Digital Publishing Institute
2021
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| Онлайн доступ: | 32199 |
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| _version_ | 1869522534568820736 |
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| author | Kenneth P. Nephew (Ed.) Joanna E. Burdette (Ed.) Anirban K. Mitra (Ed.) M. Sharon Stack (Ed.) |
| author_browse | Anirban K. Mitra (Ed.) Joanna E. Burdette (Ed.) Kenneth P. Nephew (Ed.) M. Sharon Stack (Ed.) |
| author_facet | Kenneth P. Nephew (Ed.) Joanna E. Burdette (Ed.) Anirban K. Mitra (Ed.) M. Sharon Stack (Ed.) |
| author_sort | Kenneth P. Nephew (Ed.) |
| collection | Directory of Open Access Books |
| description | The Special Issue on high grade serous ovarian cancer (HGSOC) and the contribution of the tumor microenviroment (TME) consists of reviews contributed by leaders in the OC field. As HGSOC metastases have a highly complex TME, there is an urgent need to better understand the TME in general, its distinct components in particular, and the role of the TME in the context of disease recurrence and development of chemoresistance. The Special Issue incorporates the current understanding of the different parts of thd TME components, including the cancer cells themselves, the cells surrounding the cancer cells or stromal cells, and the cells of the immune system, which are attracted to the site of metastases. In addition to these cells of the TME, the role of various cellular factors made by the cells of the TME are also the subject of the reviews. In addition, reviews in this Special Issue cover the complex relationships between the molecular mechanisms of HGSOC progression, including genomic, epigenomic and transcriptomic changes and changes in the immune cell landscape, as these may provide attractive new molecular targets for HGSOC therapy. |
| format | Online |
| id | doab-20.500.12854ir-61394 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-613942024-04-05T12:32:47Z The Tumor Microenvironment of High Grade Serous Ovarian Cancer Kenneth P. Nephew (Ed.) Joanna E. Burdette (Ed.) Anirban K. Mitra (Ed.) M. Sharon Stack (Ed.) QH301-705.5 RC254-282 ovarian cancer transcriptomic stroma immune cells epigenetics recurrence immunotherapies chemoresistance fibroblasts metastasis genomic tumor microenvironment cancer stem cells thema EDItEUR::P Mathematics and Science::PS Biology, life sciences The Special Issue on high grade serous ovarian cancer (HGSOC) and the contribution of the tumor microenviroment (TME) consists of reviews contributed by leaders in the OC field. As HGSOC metastases have a highly complex TME, there is an urgent need to better understand the TME in general, its distinct components in particular, and the role of the TME in the context of disease recurrence and development of chemoresistance. The Special Issue incorporates the current understanding of the different parts of thd TME components, including the cancer cells themselves, the cells surrounding the cancer cells or stromal cells, and the cells of the immune system, which are attracted to the site of metastases. In addition to these cells of the TME, the role of various cellular factors made by the cells of the TME are also the subject of the reviews. In addition, reviews in this Special Issue cover the complex relationships between the molecular mechanisms of HGSOC progression, including genomic, epigenomic and transcriptomic changes and changes in the immune cell landscape, as these may provide attractive new molecular targets for HGSOC therapy. 2021-02-12T06:41:43Z 2021-02-12T06:41:43Z 2019-02-06 09:22:42 2019 book 32199 9783038975540 9783038975557 https://directory.doabooks.org/handle/20.500.12854/61394 eng image/jpeg Attribution-NonCommercial-NoDerivatives 4.0 International https://www.mdpi.com/books/pdfview/book/1127 https://play.google.com/books/publish/a/14935057684283403269#details/ISBN:9783038975540 https://www.mdpi.com/books/pdfview/book/1127 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-03897-555-7 10.3390/books978-3-03897-555-7 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783038975540 9783038975557 434 open access |
| spellingShingle | QH301-705.5 RC254-282 ovarian cancer transcriptomic stroma immune cells epigenetics recurrence immunotherapies chemoresistance fibroblasts metastasis genomic tumor microenvironment cancer stem cells thema EDItEUR::P Mathematics and Science::PS Biology, life sciences Kenneth P. Nephew (Ed.) Joanna E. Burdette (Ed.) Anirban K. Mitra (Ed.) M. Sharon Stack (Ed.) The Tumor Microenvironment of High Grade Serous Ovarian Cancer |
| title | The Tumor Microenvironment of High Grade Serous Ovarian Cancer |
| title_full | The Tumor Microenvironment of High Grade Serous Ovarian Cancer |
| title_fullStr | The Tumor Microenvironment of High Grade Serous Ovarian Cancer |
| title_full_unstemmed | The Tumor Microenvironment of High Grade Serous Ovarian Cancer |
| title_short | The Tumor Microenvironment of High Grade Serous Ovarian Cancer |
| title_sort | tumor microenvironment of high grade serous ovarian cancer |
| topic | QH301-705.5 RC254-282 ovarian cancer transcriptomic stroma immune cells epigenetics recurrence immunotherapies chemoresistance fibroblasts metastasis genomic tumor microenvironment cancer stem cells thema EDItEUR::P Mathematics and Science::PS Biology, life sciences |
| topic_facet | QH301-705.5 RC254-282 ovarian cancer transcriptomic stroma immune cells epigenetics recurrence immunotherapies chemoresistance fibroblasts metastasis genomic tumor microenvironment cancer stem cells thema EDItEUR::P Mathematics and Science::PS Biology, life sciences |
| url | 32199 |
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