An Updated View on an Emerging Target: Selected Papers from the 8th International Conference on Protein Kinase CK2
The 8th International Conference on Protein Kinase CK2 (www.uks.eu/ck2), organized by Matthias Montenarh and Claudia Götz, will be held at the Faculty of Medicine of Saarland University, in Homburg, Germany, from 6–9 September, 2016. Protein kinase CK2 is a serine/threonine kinase, which is highly c...
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| Format: | Online |
| Język: | angielski |
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MDPI - Multidisciplinary Digital Publishing Institute
2021
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| Dostęp online: | 23024 |
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| _version_ | 1869528611017457664 |
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| author | Lorenzo A. Pinna (Ed.) Joachim Jose (Ed.) Marc Le Borgne (Ed.) Mathias Montenarh (Ed.) |
| author_browse | Joachim Jose (Ed.) Lorenzo A. Pinna (Ed.) Marc Le Borgne (Ed.) Mathias Montenarh (Ed.) |
| author_facet | Lorenzo A. Pinna (Ed.) Joachim Jose (Ed.) Marc Le Borgne (Ed.) Mathias Montenarh (Ed.) |
| author_sort | Lorenzo A. Pinna (Ed.) |
| collection | Directory of Open Access Books |
| description | The 8th International Conference on Protein Kinase CK2 (www.uks.eu/ck2), organized by Matthias Montenarh and Claudia Götz, will be held at the Faculty of Medicine of Saarland University, in Homburg, Germany, from 6–9 September, 2016. Protein kinase CK2 is a serine/threonine kinase, which is highly conserved in evolution. Knock-out experiments have shown that this enzyme is absolutely necessary for cell viability. The enzyme is highly expressed in rapidly proliferating cells, which goes along with an elevated enzyme activity. Protein kinase CK2 is involved in a broad range of signaling pathways, regulating proliferation, differentiation, apoptosis, or senescence. Recent advances towards the characterization of the three-dimensional structure of protein kinase CK2 and its subunits will undoubtedly yield important new insights into its regulation, and the functions of CK2. Moreover, with two inhibitors of the enzyme presently in clinical phase II trials, human protein kinase CK2 has appeared as an emerging target for cancer diseases. |
| format | Online |
| id | doab-20.500.12854ir-61731 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-617312024-03-31T13:10:00Z An Updated View on an Emerging Target: Selected Papers from the 8th International Conference on Protein Kinase CK2 Lorenzo A. Pinna (Ed.) Joachim Jose (Ed.) Marc Le Borgne (Ed.) Mathias Montenarh (Ed.) R5-920 cancer disease signal transduction therapeutic target structural biology protein kinase thema EDItEUR::M Medicine and Nursing The 8th International Conference on Protein Kinase CK2 (www.uks.eu/ck2), organized by Matthias Montenarh and Claudia Götz, will be held at the Faculty of Medicine of Saarland University, in Homburg, Germany, from 6–9 September, 2016. Protein kinase CK2 is a serine/threonine kinase, which is highly conserved in evolution. Knock-out experiments have shown that this enzyme is absolutely necessary for cell viability. The enzyme is highly expressed in rapidly proliferating cells, which goes along with an elevated enzyme activity. Protein kinase CK2 is involved in a broad range of signaling pathways, regulating proliferation, differentiation, apoptosis, or senescence. Recent advances towards the characterization of the three-dimensional structure of protein kinase CK2 and its subunits will undoubtedly yield important new insights into its regulation, and the functions of CK2. Moreover, with two inhibitors of the enzyme presently in clinical phase II trials, human protein kinase CK2 has appeared as an emerging target for cancer diseases. 2021-02-12T07:10:24Z 2021-02-12T07:10:24Z 2017-07-12 07:57:21 2017 book 23024 9783038424130 9783038424123 https://directory.doabooks.org/handle/20.500.12854/61731 eng application/octet-stream Attribution-NonCommercial-NoDerivatives 4.0 International http://www.mdpi.com/books/pdfview/book/292 http://www.mdpi.com/books/pdfview/book/292 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-03842-413-0 10.3390/books978-3-03842-413-0 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783038424130 9783038424123 320 open access |
| spellingShingle | R5-920 cancer disease signal transduction therapeutic target structural biology protein kinase thema EDItEUR::M Medicine and Nursing Lorenzo A. Pinna (Ed.) Joachim Jose (Ed.) Marc Le Borgne (Ed.) Mathias Montenarh (Ed.) An Updated View on an Emerging Target: Selected Papers from the 8th International Conference on Protein Kinase CK2 |
| title | An Updated View on an Emerging Target: Selected Papers from the 8th International Conference on Protein Kinase CK2 |
| title_full | An Updated View on an Emerging Target: Selected Papers from the 8th International Conference on Protein Kinase CK2 |
| title_fullStr | An Updated View on an Emerging Target: Selected Papers from the 8th International Conference on Protein Kinase CK2 |
| title_full_unstemmed | An Updated View on an Emerging Target: Selected Papers from the 8th International Conference on Protein Kinase CK2 |
| title_short | An Updated View on an Emerging Target: Selected Papers from the 8th International Conference on Protein Kinase CK2 |
| title_sort | updated view on an emerging target selected papers from the 8th international conference on protein kinase ck2 |
| topic | R5-920 cancer disease signal transduction therapeutic target structural biology protein kinase thema EDItEUR::M Medicine and Nursing |
| topic_facet | R5-920 cancer disease signal transduction therapeutic target structural biology protein kinase thema EDItEUR::M Medicine and Nursing |
| url | 23024 |
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