Virus Discovery by Metagenomics: The (Im)possibilities

Since the late 1800s, the discovery of new viruses was a gradual process. Viruses were described one by one using a suite of techniques such as (electron) microscopy and viral culture. Investigators were usually interested in a disease state within an organism, and expeditions in viral ecology were...

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Main Authors: Katrine L. Whiteson, Alejandro Reyes, Richard J. Hall, Bas E. Dutilh
Formato: Online
Idioma:inglês
Publicado em: Frontiers Media SA 2021
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Acesso em linha:25616
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author Katrine L. Whiteson
Alejandro Reyes
Richard J. Hall
Bas E. Dutilh
author_browse Alejandro Reyes
Bas E. Dutilh
Katrine L. Whiteson
Richard J. Hall
author_facet Katrine L. Whiteson
Alejandro Reyes
Richard J. Hall
Bas E. Dutilh
author_sort Katrine L. Whiteson
collection Directory of Open Access Books
description Since the late 1800s, the discovery of new viruses was a gradual process. Viruses were described one by one using a suite of techniques such as (electron) microscopy and viral culture. Investigators were usually interested in a disease state within an organism, and expeditions in viral ecology were rare. The advent of metagenomics using high-throughput sequencing has revolutionized not only the rate of virus discovery, but also the nature of the discoveries. For example, the viral ecology and etiology of many human diseases are being characterized, non-pathogenic viral commensals are ubiquitous, and the description of environmental viromes is making progress. This Frontiers in Virology Research Topic showcases how metagenomic and bioinformatic approaches have been combined to discover, classify and characterize novel viruses.
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spelling doab-20.500.12854ir-622492024-04-05T17:31:07Z Virus Discovery by Metagenomics: The (Im)possibilities Katrine L. Whiteson Alejandro Reyes Richard J. Hall Bas E. Dutilh QR1-502 Q1-390 virome biological dark matter metagenome metagenomics bacteriophages bioinformatics virus discovery phages thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSG Microbiology (non-medical) Since the late 1800s, the discovery of new viruses was a gradual process. Viruses were described one by one using a suite of techniques such as (electron) microscopy and viral culture. Investigators were usually interested in a disease state within an organism, and expeditions in viral ecology were rare. The advent of metagenomics using high-throughput sequencing has revolutionized not only the rate of virus discovery, but also the nature of the discoveries. For example, the viral ecology and etiology of many human diseases are being characterized, non-pathogenic viral commensals are ubiquitous, and the description of environmental viromes is making progress. This Frontiers in Virology Research Topic showcases how metagenomic and bioinformatic approaches have been combined to discover, classify and characterize novel viruses. 2021-02-12T07:54:02Z 2021-02-12T07:54:02Z 2018-02-27 16:16:45 2017 book 25616 16648714 9782889453085 https://directory.doabooks.org/handle/20.500.12854/62249 eng Frontiers Research Topics image/jpeg Attribution 4.0 International https://www.frontiersin.org/books/Virus_Discovery_by_Metagenomics_The_Impossibilities/1364 https://www.frontiersin.org/research-topics/2708/virus-discovery-by-metagenomics-the-impossibilities Frontiers Media SA 10.3389/978-2-88945-308-5 10.3389/978-2-88945-308-5 bf5ce210-e72e-4860-ba9b-c305640ff3ae 9782889453085 216 open access
spellingShingle QR1-502
Q1-390
virome
biological dark matter
metagenome
metagenomics
bacteriophages
bioinformatics
virus discovery
phages
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSG Microbiology (non-medical)
Katrine L. Whiteson
Alejandro Reyes
Richard J. Hall
Bas E. Dutilh
Virus Discovery by Metagenomics: The (Im)possibilities
title Virus Discovery by Metagenomics: The (Im)possibilities
title_full Virus Discovery by Metagenomics: The (Im)possibilities
title_fullStr Virus Discovery by Metagenomics: The (Im)possibilities
title_full_unstemmed Virus Discovery by Metagenomics: The (Im)possibilities
title_short Virus Discovery by Metagenomics: The (Im)possibilities
title_sort virus discovery by metagenomics the im possibilities
topic QR1-502
Q1-390
virome
biological dark matter
metagenome
metagenomics
bacteriophages
bioinformatics
virus discovery
phages
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSG Microbiology (non-medical)
topic_facet QR1-502
Q1-390
virome
biological dark matter
metagenome
metagenomics
bacteriophages
bioinformatics
virus discovery
phages
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSG Microbiology (non-medical)
url 25616
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