Vitamin C and Human Health
Ascorbic acid is a small, simple, water soluble molecule, synthesised by most plants and animals, with the exception of humans and some animal species due to mutations in the gene encoding the terminal enzyme in the biosynthetic pathway. For humans, it is thus a vitamin (vitamin C) that must be obta...
-д хадгалсан:
| Формат: | Online |
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| Хэл сонгох: | англи |
| Хэвлэсэн: |
MDPI - Multidisciplinary Digital Publishing Institute
2021
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| Нөхцлүүд: | |
| Онлайн хандалт: | 16629 |
| Шошгууд: |
Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!
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| _version_ | 1869527781270880256 |
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| collection | Directory of Open Access Books |
| description | Ascorbic acid is a small, simple, water soluble molecule, synthesised by most plants and animals, with the exception of humans and some animal species due to mutations in the gene encoding the terminal enzyme in the biosynthetic pathway. For humans, it is thus a vitamin (vitamin C) that must be obtained from the diet, with complete deficiency resulting in the fatal disease scurvy. Many functions have been attributed to this fascinating molecule and, despite nearly 90 years of research since its discovery, new roles are still being uncovered, including recent discoveries that it acts as a regulator of epigenetic marks and transcription factors (1). In this volume we begin with a review by Michels and Frei on specific factors that need to be taken into consideration when carrying out vitamin C research. Translational research normally comprises a progression from in vitro/cell culture studies to animal models and finally to clinical trials. At each of these stages, there are requirements specific to vitamin C research that need to be integrated into study designs and this review describes these in detail. [...] |
| format | Online |
| id | doab-20.500.12854ir-62302 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-623022022-01-31T19:27:43Z Vitamin C and Human Health cardiovascular disease bioavailability gene regulation inflammation cancer neurological effects vitamin C-dependent enzymes human status Ascorbic acid is a small, simple, water soluble molecule, synthesised by most plants and animals, with the exception of humans and some animal species due to mutations in the gene encoding the terminal enzyme in the biosynthetic pathway. For humans, it is thus a vitamin (vitamin C) that must be obtained from the diet, with complete deficiency resulting in the fatal disease scurvy. Many functions have been attributed to this fascinating molecule and, despite nearly 90 years of research since its discovery, new roles are still being uncovered, including recent discoveries that it acts as a regulator of epigenetic marks and transcription factors (1). In this volume we begin with a review by Michels and Frei on specific factors that need to be taken into consideration when carrying out vitamin C research. Translational research normally comprises a progression from in vitro/cell culture studies to animal models and finally to clinical trials. At each of these stages, there are requirements specific to vitamin C research that need to be integrated into study designs and this review describes these in detail. [...] 2021-02-12T08:00:13Z 2021-02-12T08:00:13Z 2015-01-12 11:52:06 2014 book 16629 9783906980614 9783906980621 https://directory.doabooks.org/handle/20.500.12854/62302 eng application/octet-stream Attribution 4.0 International https://www.mdpi.com/books/pdfview/book/93 https://www.mdpi.com/books/pdfview/book/93 MDPI - Multidisciplinary Digital Publishing Institute 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783906980614 9783906980621 236 open access |
| spellingShingle | cardiovascular disease bioavailability gene regulation inflammation cancer neurological effects vitamin C-dependent enzymes human status Vitamin C and Human Health |
| title | Vitamin C and Human Health |
| title_full | Vitamin C and Human Health |
| title_fullStr | Vitamin C and Human Health |
| title_full_unstemmed | Vitamin C and Human Health |
| title_short | Vitamin C and Human Health |
| title_sort | vitamin c and human health |
| topic | cardiovascular disease bioavailability gene regulation inflammation cancer neurological effects vitamin C-dependent enzymes human status |
| topic_facet | cardiovascular disease bioavailability gene regulation inflammation cancer neurological effects vitamin C-dependent enzymes human status |
| url | 16629 |