Vitamin D and Human Health

Over the past decades, researchers have gathered data demonstrating that vitamin D and its metabolites possess activities far beyond the classic regulation of calcium–phosphate homeostasis. It is now well established that vitamin D is essential for the proper functioning of the musculoskeletal, card...

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Автор: Simon Spedding (Ed.)
Формат: Online
Мова:Англійська
Опубліковано: MDPI - Multidisciplinary Digital Publishing Institute 2021
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Онлайн доступ:32271
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author Simon Spedding (Ed.)
author_browse Simon Spedding (Ed.)
author_facet Simon Spedding (Ed.)
author_sort Simon Spedding (Ed.)
collection Directory of Open Access Books
description Over the past decades, researchers have gathered data demonstrating that vitamin D and its metabolites possess activities far beyond the classic regulation of calcium–phosphate homeostasis. It is now well established that vitamin D is essential for the proper functioning of the musculoskeletal, cardiovascular, nervous, and immune systems. Furthermore, vitamin D and its analogs were shown to regulate proliferation and differentiation of keratinocyte, immune cells, and numerous cancer-derived cells, both in vivo and in vitro. On the other hand, population base studies have provided evidence that global vitamin D deficiency is correlated with the occurrence and aggravation of symptoms of skeletal, cardiovascular autoimmune, and skin disease; infections; metabolic and cognitive disorders; multiple types of cancers; as well as overall mortality. This Special Issue of International Journal of Molecular Sciences, entitled “Vitamin D and Human Health”, summarizes recent advances in our understanding of pleiotropic activity of vitamin D with a focus on its protective role against cancer, hypertension, viral infections, and neurological diseases, as well as its impact on the immune system and mitochondria. Furthermore, eight research papers provide new insight into vitamin D research and highlight new directions and targets in the prevention and treatment of human diseases.
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spelling doab-20.500.12854ir-623062024-04-05T12:32:37Z Vitamin D and Human Health Simon Spedding (Ed.) QH301-705.5 Vitamin D supplementation extra-skeletal effects analogs of vitamin D therapy and prevention vitamin D deficiency vitamin D activity and metabolism thema EDItEUR::P Mathematics and Science::PS Biology, life sciences Over the past decades, researchers have gathered data demonstrating that vitamin D and its metabolites possess activities far beyond the classic regulation of calcium–phosphate homeostasis. It is now well established that vitamin D is essential for the proper functioning of the musculoskeletal, cardiovascular, nervous, and immune systems. Furthermore, vitamin D and its analogs were shown to regulate proliferation and differentiation of keratinocyte, immune cells, and numerous cancer-derived cells, both in vivo and in vitro. On the other hand, population base studies have provided evidence that global vitamin D deficiency is correlated with the occurrence and aggravation of symptoms of skeletal, cardiovascular autoimmune, and skin disease; infections; metabolic and cognitive disorders; multiple types of cancers; as well as overall mortality. This Special Issue of International Journal of Molecular Sciences, entitled “Vitamin D and Human Health”, summarizes recent advances in our understanding of pleiotropic activity of vitamin D with a focus on its protective role against cancer, hypertension, viral infections, and neurological diseases, as well as its impact on the immune system and mitochondria. Furthermore, eight research papers provide new insight into vitamin D research and highlight new directions and targets in the prevention and treatment of human diseases. 2021-02-12T08:00:34Z 2021-02-12T08:00:34Z 2019-02-21 10:04:11 2019 book 32271 9783038975861 9783038975878 https://directory.doabooks.org/handle/20.500.12854/62306 eng image/jpeg Attribution-NonCommercial-NoDerivatives 4.0 International https://play.google.com/books/publish/u/0/a/14935057684283403269#details/ISBN:9783038975861 https://www.mdpi.com/books/pdfview/book/1147 https://www.mdpi.com/books/pdfview/book/1147 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-03897-587-8 10.3390/books978-3-03897-587-8 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783038975861 9783038975878 306 open access
spellingShingle QH301-705.5
Vitamin D
supplementation
extra-skeletal effects
analogs of vitamin D
therapy and prevention
vitamin D deficiency
vitamin D activity and metabolism
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
Simon Spedding (Ed.)
Vitamin D and Human Health
title Vitamin D and Human Health
title_full Vitamin D and Human Health
title_fullStr Vitamin D and Human Health
title_full_unstemmed Vitamin D and Human Health
title_short Vitamin D and Human Health
title_sort vitamin d and human health
topic QH301-705.5
Vitamin D
supplementation
extra-skeletal effects
analogs of vitamin D
therapy and prevention
vitamin D deficiency
vitamin D activity and metabolism
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
topic_facet QH301-705.5
Vitamin D
supplementation
extra-skeletal effects
analogs of vitamin D
therapy and prevention
vitamin D deficiency
vitamin D activity and metabolism
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
url 32271
work_keys_str_mv AT simonspeddinged vitamindandhumanhealth