Vitamin E

Vitamin E is the major lipid-soluble antioxidant in the cell antioxidant system and is exclusively obtained from the diet. In 1922, vitamin E was discovered as a dietary factor essential for reproduction in rats. Meanwhile, vitamin E has revealed many more important molecular properties, such as the...

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Prif Awdur: Volker Böhm (Ed.)
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Iaith:Saesneg
Cyhoeddwyd: MDPI - Multidisciplinary Digital Publishing Institute 2021
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Mynediad Ar-lein:26845
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author Volker Böhm (Ed.)
author_browse Volker Böhm (Ed.)
author_facet Volker Böhm (Ed.)
author_sort Volker Böhm (Ed.)
collection Directory of Open Access Books
description Vitamin E is the major lipid-soluble antioxidant in the cell antioxidant system and is exclusively obtained from the diet. In 1922, vitamin E was discovered as a dietary factor essential for reproduction in rats. Meanwhile, vitamin E has revealed many more important molecular properties, such as the scavenging of reactive oxygen and nitrogen species with consequent prevention of the oxidative damage associated with many diseases. In addition, the modulation of signal transduction and gene expression in antioxidant and non-antioxidant manners was shown for vitamin E. This Special Issue highlights some of the recent advances in vitamin E research, showing on the one hand the status quo and providing, on the other hand, new insights into functions and physiological relevance. Thus, the current knowledge of tocochromanol biosynthesis in plants and future challenges regarding the understanding of its regulation are presented. Another paper describes the fate of vitamin E in the human gastrointestinal lumen during digestion. During the metabolism of vitamin E, the long-chain metabolites 13’-hydroxychromanol and 13’-carboxychromanol are formed by oxidative modification of the side-chain. Their occurrence in human serum indicates a physiological relevance. Another paper describes the membrane distribution of α-tocopherol in brain regions of adult rhesus monkeys, also looking for associations between membrane α-tocopherol and the content of polyunsaturated fatty acids.
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publisherStr MDPI - Multidisciplinary Digital Publishing Institute
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spelling doab-20.500.12854ir-623072022-01-31T19:13:14Z Vitamin E Volker Böhm (Ed.) nonalcoholic fatty liver disease long-chain metabolites biosynthesis almond digestion female reproductive health brain radiation countermeasures Vitamin E is the major lipid-soluble antioxidant in the cell antioxidant system and is exclusively obtained from the diet. In 1922, vitamin E was discovered as a dietary factor essential for reproduction in rats. Meanwhile, vitamin E has revealed many more important molecular properties, such as the scavenging of reactive oxygen and nitrogen species with consequent prevention of the oxidative damage associated with many diseases. In addition, the modulation of signal transduction and gene expression in antioxidant and non-antioxidant manners was shown for vitamin E. This Special Issue highlights some of the recent advances in vitamin E research, showing on the one hand the status quo and providing, on the other hand, new insights into functions and physiological relevance. Thus, the current knowledge of tocochromanol biosynthesis in plants and future challenges regarding the understanding of its regulation are presented. Another paper describes the fate of vitamin E in the human gastrointestinal lumen during digestion. During the metabolism of vitamin E, the long-chain metabolites 13’-hydroxychromanol and 13’-carboxychromanol are formed by oxidative modification of the side-chain. Their occurrence in human serum indicates a physiological relevance. Another paper describes the membrane distribution of α-tocopherol in brain regions of adult rhesus monkeys, also looking for associations between membrane α-tocopherol and the content of polyunsaturated fatty acids. 2021-02-12T08:00:39Z 2021-02-12T08:00:39Z 2018-05-22 09:52:09 2018 book 26845 9783038429067 9783038429050 https://directory.doabooks.org/handle/20.500.12854/62307 eng image/png Attribution-NonCommercial-NoDerivatives 4.0 International http://www.mdpi.com/books/pdfview/book/635 http://www.mdpi.com/books/pdfview/book/635 MDPI - Multidisciplinary Digital Publishing Institute 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783038429067 9783038429050 VIII, 150 open access
spellingShingle nonalcoholic fatty liver disease
long-chain metabolites
biosynthesis
almond
digestion
female reproductive health
brain
radiation countermeasures
Volker Böhm (Ed.)
Vitamin E
title Vitamin E
title_full Vitamin E
title_fullStr Vitamin E
title_full_unstemmed Vitamin E
title_short Vitamin E
title_sort vitamin e
topic nonalcoholic fatty liver disease
long-chain metabolites
biosynthesis
almond
digestion
female reproductive health
brain
radiation countermeasures
topic_facet nonalcoholic fatty liver disease
long-chain metabolites
biosynthesis
almond
digestion
female reproductive health
brain
radiation countermeasures
url 26845
work_keys_str_mv AT volkerbohmed vitamine