The world according to zebrafish: How neural circuits generate behaviour

Understanding how the brain functions is one of the most ambitious current scientific goals. This challenge will only be accomplish by a multidisciplinary approach involving genetics, molecular biology, optics, ethology, neurobiology and mathematics and using tractable model systems. The zebrafish l...

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Egile Nagusiak: Gonzalo G. De Polavieja, German Sumbre
Formatua: Online
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Argitaratua: Frontiers Media SA 2021
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Sarrera elektronikoa:18660
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author Gonzalo G. De Polavieja
German Sumbre
author_browse German Sumbre
Gonzalo G. De Polavieja
author_facet Gonzalo G. De Polavieja
German Sumbre
author_sort Gonzalo G. De Polavieja
collection Directory of Open Access Books
description Understanding how the brain functions is one of the most ambitious current scientific goals. This challenge will only be accomplish by a multidisciplinary approach involving genetics, molecular biology, optics, ethology, neurobiology and mathematics and using tractable model systems. The zebrafish larva is a transparent genetically tractable small vertebrate, ideal for the combination state-of-the- art imaging techniques (e.g. two-photon scanning microscopy, single-plane illumination microscopy, spatial light modulator microscopy and lightfield microscopy), bioluminiscence and optogenetics to monitor and manipulate neuronal activity from single specific neurons up to the entire brain, in an intact behaving organism. Furthermore, the zebrafish model offers large and increasing collection of mutant and transgenic lines modelling human brain diseases. With these advantages in hand, the zebrafish larva became in the recent years, a novel animal model to study neuronal circuits and behaviour, taking us closer than ever before to understand how the brain controls behaviour.
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spelling doab-20.500.12854ir-628192024-04-05T12:35:25Z The world according to zebrafish: How neural circuits generate behaviour Gonzalo G. De Polavieja German Sumbre RC321-571 Q1-390 Models of human brain disorder neuronal circuit dynamics Neuroanatomy Zebrafish Behavior thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences Understanding how the brain functions is one of the most ambitious current scientific goals. This challenge will only be accomplish by a multidisciplinary approach involving genetics, molecular biology, optics, ethology, neurobiology and mathematics and using tractable model systems. The zebrafish larva is a transparent genetically tractable small vertebrate, ideal for the combination state-of-the- art imaging techniques (e.g. two-photon scanning microscopy, single-plane illumination microscopy, spatial light modulator microscopy and lightfield microscopy), bioluminiscence and optogenetics to monitor and manipulate neuronal activity from single specific neurons up to the entire brain, in an intact behaving organism. Furthermore, the zebrafish model offers large and increasing collection of mutant and transgenic lines modelling human brain diseases. With these advantages in hand, the zebrafish larva became in the recent years, a novel animal model to study neuronal circuits and behaviour, taking us closer than ever before to understand how the brain controls behaviour. 2021-02-12T08:47:55Z 2021-02-12T08:47:55Z 2016-03-10 08:14:32 2014 book 18660 16648714 9782889193288 https://directory.doabooks.org/handle/20.500.12854/62819 eng Frontiers Research Topics image/jpeg Attribution 4.0 International http://www.frontiersin.org/books/The_world_according_to_zebrafish_How_neural_circuits_generate_behaviour/356 http://journal.frontiersin.org/researchtopic/829/the-world-according-to-zebrafish-how-neural-circuits-generate-behaviour Frontiers Media SA 10.3389/978-2-88919-328-8 10.3389/978-2-88919-328-8 bf5ce210-e72e-4860-ba9b-c305640ff3ae 9782889193288 367 open access
spellingShingle RC321-571
Q1-390
Models of human brain disorder
neuronal circuit dynamics
Neuroanatomy
Zebrafish
Behavior
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
Gonzalo G. De Polavieja
German Sumbre
The world according to zebrafish: How neural circuits generate behaviour
title The world according to zebrafish: How neural circuits generate behaviour
title_full The world according to zebrafish: How neural circuits generate behaviour
title_fullStr The world according to zebrafish: How neural circuits generate behaviour
title_full_unstemmed The world according to zebrafish: How neural circuits generate behaviour
title_short The world according to zebrafish: How neural circuits generate behaviour
title_sort world according to zebrafish how neural circuits generate behaviour
topic RC321-571
Q1-390
Models of human brain disorder
neuronal circuit dynamics
Neuroanatomy
Zebrafish
Behavior
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
topic_facet RC321-571
Q1-390
Models of human brain disorder
neuronal circuit dynamics
Neuroanatomy
Zebrafish
Behavior
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
url 18660
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