Zinc Signaling in Physiology and Pathogenesis
The essential trace element zinc plays indispensable roles in multiple cellular processes. It regulates a great number of protein functions, including transcription factors, enzymes, adapters, and growth factors as a structural and/or catalytic factor. Recent studies have highlighted another functio...
Wedi'i Gadw mewn:
| Prif Awduron: | , |
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| Fformat: | Online |
| Iaith: | Saesneg |
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MDPI - Multidisciplinary Digital Publishing Institute
2021
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| Pynciau: | |
| Mynediad Ar-lein: | 26650 |
| Tagiau: |
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!
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| _version_ | 1869531240199094272 |
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| author | Toshiyuki Fukada (Ed.) Taiho Kambe (Ed.) |
| author_browse | Taiho Kambe (Ed.) Toshiyuki Fukada (Ed.) |
| author_facet | Toshiyuki Fukada (Ed.) Taiho Kambe (Ed.) |
| author_sort | Toshiyuki Fukada (Ed.) |
| collection | Directory of Open Access Books |
| description | The essential trace element zinc plays indispensable roles in multiple cellular processes. It regulates a great number of protein functions, including transcription factors, enzymes, adapters, and growth factors as a structural and/or catalytic factor. Recent studies have highlighted another function of zinc as an intra- and intercellular signaling mediator, which became recognized as the “zinc signal”. Indeed, zinc regulates cellular signaling pathways, which enable conversion of extracellular stimuli to intracellular signals, and controls various intracellular and extracellular events, and thus zinc mediates communication between cells. The zinc signal is essential for physiology, and its dysregulation causes a variety of diseases, such as diabetes, cancer, osteoarthritis, dermatitis, and dementia. This Special Issue focuses on crucial roles of zinc signaling in biological processes in molecular and physiological basis, addressing the future directions and questions underlying this unique phenomenon. Because there is growing interest and attention in physiopathological contribution of zinc signal, we believe this Special Issue will provide very timely information on it and thus should appeal to a wide range of readers. |
| format | Online |
| id | doab-20.500.12854ir-62924 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-629242024-03-31T22:45:16Z Zinc Signaling in Physiology and Pathogenesis Toshiyuki Fukada (Ed.) Taiho Kambe (Ed.) QP1-981 QD415-436 zinc signal disease zinc transporters physiology metallothionein zinc biology receptors and channels thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFG Physiology The essential trace element zinc plays indispensable roles in multiple cellular processes. It regulates a great number of protein functions, including transcription factors, enzymes, adapters, and growth factors as a structural and/or catalytic factor. Recent studies have highlighted another function of zinc as an intra- and intercellular signaling mediator, which became recognized as the “zinc signal”. Indeed, zinc regulates cellular signaling pathways, which enable conversion of extracellular stimuli to intracellular signals, and controls various intracellular and extracellular events, and thus zinc mediates communication between cells. The zinc signal is essential for physiology, and its dysregulation causes a variety of diseases, such as diabetes, cancer, osteoarthritis, dermatitis, and dementia. This Special Issue focuses on crucial roles of zinc signaling in biological processes in molecular and physiological basis, addressing the future directions and questions underlying this unique phenomenon. Because there is growing interest and attention in physiopathological contribution of zinc signal, we believe this Special Issue will provide very timely information on it and thus should appeal to a wide range of readers. 2021-02-12T08:57:07Z 2021-02-12T08:57:07Z 2018-05-04 10:58:25 2018 book 26650 9783038428213 9783038428220 https://directory.doabooks.org/handle/20.500.12854/62924 eng image/png Attribution-NonCommercial-NoDerivatives 4.0 International http://www.mdpi.com/books/pdfview/book/607 http://www.mdpi.com/books/pdfview/book/607 MDPI - Multidisciplinary Digital Publishing Institute 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783038428213 9783038428220 X, 282 open access |
| spellingShingle | QP1-981 QD415-436 zinc signal disease zinc transporters physiology metallothionein zinc biology receptors and channels thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFG Physiology Toshiyuki Fukada (Ed.) Taiho Kambe (Ed.) Zinc Signaling in Physiology and Pathogenesis |
| title | Zinc Signaling in Physiology and Pathogenesis |
| title_full | Zinc Signaling in Physiology and Pathogenesis |
| title_fullStr | Zinc Signaling in Physiology and Pathogenesis |
| title_full_unstemmed | Zinc Signaling in Physiology and Pathogenesis |
| title_short | Zinc Signaling in Physiology and Pathogenesis |
| title_sort | zinc signaling in physiology and pathogenesis |
| topic | QP1-981 QD415-436 zinc signal disease zinc transporters physiology metallothionein zinc biology receptors and channels thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFG Physiology |
| topic_facet | QP1-981 QD415-436 zinc signal disease zinc transporters physiology metallothionein zinc biology receptors and channels thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFG Physiology |
| url | 26650 |
| work_keys_str_mv | AT toshiyukifukadaed zincsignalinginphysiologyandpathogenesis AT taihokambeed zincsignalinginphysiologyandpathogenesis |