Novel Aspects in Acute Lymphoblastic Leukemia

Acute lymphoblastic leukemia (ALL) has turned from a universally fatal to a highly curable disease in little more than four decades. Even though differences in outcome continue to exist between children and adults, intense efforts are under way to overcome this discrepancy and improve the prognosis...

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collection Directory of Open Access Books
description Acute lymphoblastic leukemia (ALL) has turned from a universally fatal to a highly curable disease in little more than four decades. Even though differences in outcome continue to exist between children and adults, intense efforts are under way to overcome this discrepancy and improve the prognosis of adult patients as well. This exemplary progress in ALL therapy has been possible by the combination of an increasingly better understanding of the biology of the disease, availability of a range of effective drugs, and astute designs and relentless executions of many clinical trials. ALL is a complex disease requiring complex therapy. Whereas this book cannot provide a comprehensive review of every one of its many facets, the chapters from many investigators from around the world nevertheless cover a number of relevant topics: aspects of the epidemiology of ALL in Hispanics, ophthalmologic manifestations of ALL, overviews of current therapy and drug-resistance mechanisms, novel biological pathways and targets, new drugs in development, and long-term consequences of CNS prophylaxis and therapy. The publishers and editor therefore hope that the prospective readers will find enough insight and information for their own endeavors.
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spelling doab-20.500.12854ir-653032024-03-31T22:45:58Z Novel Aspects in Acute Lymphoblastic Leukemia Faderl, Stefan Oncology thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology Acute lymphoblastic leukemia (ALL) has turned from a universally fatal to a highly curable disease in little more than four decades. Even though differences in outcome continue to exist between children and adults, intense efforts are under way to overcome this discrepancy and improve the prognosis of adult patients as well. This exemplary progress in ALL therapy has been possible by the combination of an increasingly better understanding of the biology of the disease, availability of a range of effective drugs, and astute designs and relentless executions of many clinical trials. ALL is a complex disease requiring complex therapy. Whereas this book cannot provide a comprehensive review of every one of its many facets, the chapters from many investigators from around the world nevertheless cover a number of relevant topics: aspects of the epidemiology of ALL in Hispanics, ophthalmologic manifestations of ALL, overviews of current therapy and drug-resistance mechanisms, novel biological pathways and targets, new drugs in development, and long-term consequences of CNS prophylaxis and therapy. The publishers and editor therefore hope that the prospective readers will find enough insight and information for their own endeavors. 2021-04-20T15:14:01Z 2021-04-20T15:14:01Z 2011 book ONIX_20210420_9789533077536_660 9789533077536 9789535165736 https://directory.doabooks.org/handle/20.500.12854/65303 eng image/jpeg n/a https://www.intechopen.com/books https://mts.intechopen.com/storage/books/539/authors_book/authors_book.pdf IntechOpen IntechOpen 10.5772/1050 10.5772/1050 78a36484-2c0c-47cb-ad67-2b9f5cd4a8f6 9789533077536 9789535165736 IntechOpen 272 open access
spellingShingle Oncology
thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
Novel Aspects in Acute Lymphoblastic Leukemia
title Novel Aspects in Acute Lymphoblastic Leukemia
title_full Novel Aspects in Acute Lymphoblastic Leukemia
title_fullStr Novel Aspects in Acute Lymphoblastic Leukemia
title_full_unstemmed Novel Aspects in Acute Lymphoblastic Leukemia
title_short Novel Aspects in Acute Lymphoblastic Leukemia
title_sort novel aspects in acute lymphoblastic leukemia
topic Oncology
thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
topic_facet Oncology
thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
url ONIX_20210420_9789533077536_660