Muscle Biopsy

Investigation of muscle diseases has changed dramatically with the understanding of genetic basis of a wide range of muscle diseases. Muscle biopsy has become a powerful tool not only to provide diagnosis but to make tissue available for genetic studies and to basic scientists for biomedical researc...

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collection Directory of Open Access Books
description Investigation of muscle diseases has changed dramatically with the understanding of genetic basis of a wide range of muscle diseases. Muscle biopsy has become a powerful tool not only to provide diagnosis but to make tissue available for genetic studies and to basic scientists for biomedical research. Accurate interpretation of muscle biopsy to detect cell dysfunction/ damage/death or absence / abnormality of a protein or genetic defect by the sophisticated technologies is important to guide treatment of various muscle diseases. In this book on muscle biopsy various chapters deal with the procedure and interpretation of muscle biopsy, its use in the culture of myotubes and membrane transport studies.Muscle biopsy is an important technique to investigate mitochondrial dysfunction and the mitochondrial DNA integrity in oxidation. Phosphorylation in various metabolic diseases like obesity, type 2 diabetes mellitus and peripheral vascular disease is explored in the other chapters with detailed descriptions on methodology. This book provides the advances in the basic techniques of muscle biopsy for a neuroscientist.
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spelling doab-20.500.12854ir-654022024-04-01T14:12:48Z Muscle Biopsy Sundaram, Challa Histopathology thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKF Pathology Investigation of muscle diseases has changed dramatically with the understanding of genetic basis of a wide range of muscle diseases. Muscle biopsy has become a powerful tool not only to provide diagnosis but to make tissue available for genetic studies and to basic scientists for biomedical research. Accurate interpretation of muscle biopsy to detect cell dysfunction/ damage/death or absence / abnormality of a protein or genetic defect by the sophisticated technologies is important to guide treatment of various muscle diseases. In this book on muscle biopsy various chapters deal with the procedure and interpretation of muscle biopsy, its use in the culture of myotubes and membrane transport studies.Muscle biopsy is an important technique to investigate mitochondrial dysfunction and the mitochondrial DNA integrity in oxidation. Phosphorylation in various metabolic diseases like obesity, type 2 diabetes mellitus and peripheral vascular disease is explored in the other chapters with detailed descriptions on methodology. This book provides the advances in the basic techniques of muscle biopsy for a neuroscientist. 2021-04-20T15:16:18Z 2021-04-20T15:16:18Z 2012 book ONIX_20210420_9789533077789_759 9789533077789 9789535166221 https://directory.doabooks.org/handle/20.500.12854/65402 eng image/jpeg n/a https://www.intechopen.com/books https://mts.intechopen.com/storage/books/733/authors_book/authors_book.pdf IntechOpen IntechOpen 10.5772/1241 10.5772/1241 78a36484-2c0c-47cb-ad67-2b9f5cd4a8f6 9789533077789 9789535166221 IntechOpen 164 open access
spellingShingle Histopathology
thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKF Pathology
Muscle Biopsy
title Muscle Biopsy
title_full Muscle Biopsy
title_fullStr Muscle Biopsy
title_full_unstemmed Muscle Biopsy
title_short Muscle Biopsy
title_sort muscle biopsy
topic Histopathology
thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKF Pathology
topic_facet Histopathology
thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKF Pathology
url ONIX_20210420_9789533077789_759