Multiple Myeloma
Multiple myeloma is a malignant disorder characterized by the proliferation of plasma cells. Much insight has been gained into the molecular pathways that lead to myeloma and indeed much more remains to be done. The understanding of these pathways is closely linked to their therapeutic implications...
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| Format: | Online |
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| Jezik: | angleščina |
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IntechOpen
2021
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| Teme: | |
| Online dostop: | ONIX_20210420_9789533077680_806 |
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| _version_ | 1869519278406893568 |
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| collection | Directory of Open Access Books |
| description | Multiple myeloma is a malignant disorder characterized by the proliferation of plasma cells. Much insight has been gained into the molecular pathways that lead to myeloma and indeed much more remains to be done. The understanding of these pathways is closely linked to their therapeutic implications and is stressed upon in the initial chapters. Recently, the introduction of newer agents such as bortezomib, lenalidomide, thalidomide, liposomal doxorubicin, etc. has led to a flurry of trials aimed at testing various combinations in order to improve survival. Higher response rates observed with these agents have led to their integration into induction therapies. The role of various new therapies vis a vis transplantation has also been examined. Recent advances in the management of plasmacytomas , renal dysfunction, dentistry as well as mobilization of stem cells in the context of myeloma have also found exclusive mention. Since brevity is the soul of wit our attempt has been to present before the reader a comprehensive yet brief text on this important subject. |
| format | Online |
| id | doab-20.500.12854ir-65449 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | IntechOpen |
| publisherStr | IntechOpen |
| record_format | ojs |
| spelling | doab-20.500.12854ir-654492024-03-31T22:45:53Z Multiple Myeloma Gupta, Ajay Oncology thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology Multiple myeloma is a malignant disorder characterized by the proliferation of plasma cells. Much insight has been gained into the molecular pathways that lead to myeloma and indeed much more remains to be done. The understanding of these pathways is closely linked to their therapeutic implications and is stressed upon in the initial chapters. Recently, the introduction of newer agents such as bortezomib, lenalidomide, thalidomide, liposomal doxorubicin, etc. has led to a flurry of trials aimed at testing various combinations in order to improve survival. Higher response rates observed with these agents have led to their integration into induction therapies. The role of various new therapies vis a vis transplantation has also been examined. Recent advances in the management of plasmacytomas , renal dysfunction, dentistry as well as mobilization of stem cells in the context of myeloma have also found exclusive mention. Since brevity is the soul of wit our attempt has been to present before the reader a comprehensive yet brief text on this important subject. 2021-04-20T15:17:35Z 2021-04-20T15:17:35Z 2012 book ONIX_20210420_9789533077680_806 9789533077680 9789535166368 https://directory.doabooks.org/handle/20.500.12854/65449 eng image/jpeg n/a https://www.intechopen.com/books https://mts.intechopen.com/storage/books/732/authors_book/authors_book.pdf IntechOpen IntechOpen 10.5772/1240 10.5772/1240 78a36484-2c0c-47cb-ad67-2b9f5cd4a8f6 9789533077680 9789535166368 IntechOpen 286 open access |
| spellingShingle | Oncology thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology Multiple Myeloma |
| title | Multiple Myeloma |
| title_full | Multiple Myeloma |
| title_fullStr | Multiple Myeloma |
| title_full_unstemmed | Multiple Myeloma |
| title_short | Multiple Myeloma |
| title_sort | multiple myeloma |
| topic | Oncology thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology |
| topic_facet | Oncology thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology |
| url | ONIX_20210420_9789533077680_806 |