Chronic Pancreatitis

Chronic pancreatitis is a disease of diverse etiologies in which pain can be devastating, severely impairing quality of life, and treatment is a challenge. This book covers cutting edge basic science research and clinical diagnosis and treatment issues in chronic pancreatitis. Basic science chapters...

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Almmustuhtton: IntechOpen 2021
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Liŋkkat:ONIX_20210420_9789535100119_924
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collection Directory of Open Access Books
description Chronic pancreatitis is a disease of diverse etiologies in which pain can be devastating, severely impairing quality of life, and treatment is a challenge. This book covers cutting edge basic science research and clinical diagnosis and treatment issues in chronic pancreatitis. Basic science chapters include studies on amelioration of chronic pancreatitis in rats by bone marrow derived mesenchymal cells; on gene therapy using HSV-Enkephalin to reduce fibrosis, inflammation and pain in a rats; and on pancreatic acinar and island neogenesis according to vascular and matrix dynamics of human and animal tissue. In regard to the clinical aspects, the role of endoscopic ultrasound in detecting the changes of chronic pancreatitis are addressed as well as the endoscopic treatment via duct drainage procedures or stone removal. Finally, the surgical options for chronic pancreatitis (there are well over 20 procedures) are extensively discussed, with a final chapter on total pancreatectomy and islet autotransplant to definitively remove the root cause of the pain with preservation of endocrine function. This book will be valued by basic scientists and clinicians striving to understand the mechanisms of pain in chronic pancreatitis and the treatment options in patients so afflicted.
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spelling doab-20.500.12854ir-655672024-03-31T22:44:15Z Chronic Pancreatitis Sutherland, David Hepatology thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJG Endocrinology Chronic pancreatitis is a disease of diverse etiologies in which pain can be devastating, severely impairing quality of life, and treatment is a challenge. This book covers cutting edge basic science research and clinical diagnosis and treatment issues in chronic pancreatitis. Basic science chapters include studies on amelioration of chronic pancreatitis in rats by bone marrow derived mesenchymal cells; on gene therapy using HSV-Enkephalin to reduce fibrosis, inflammation and pain in a rats; and on pancreatic acinar and island neogenesis according to vascular and matrix dynamics of human and animal tissue. In regard to the clinical aspects, the role of endoscopic ultrasound in detecting the changes of chronic pancreatitis are addressed as well as the endoscopic treatment via duct drainage procedures or stone removal. Finally, the surgical options for chronic pancreatitis (there are well over 20 procedures) are extensively discussed, with a final chapter on total pancreatectomy and islet autotransplant to definitively remove the root cause of the pain with preservation of endocrine function. This book will be valued by basic scientists and clinicians striving to understand the mechanisms of pain in chronic pancreatitis and the treatment options in patients so afflicted. 2021-04-20T15:20:27Z 2021-04-20T15:20:27Z 2012 book ONIX_20210420_9789535100119_924 9789535100119 9789535167976 https://directory.doabooks.org/handle/20.500.12854/65567 eng image/jpeg n/a https://www.intechopen.com/books https://mts.intechopen.com/storage/books/649/authors_book/authors_book.pdf IntechOpen IntechOpen 10.5772/1158 10.5772/1158 78a36484-2c0c-47cb-ad67-2b9f5cd4a8f6 9789535100119 9789535167976 IntechOpen 154 open access
spellingShingle Hepatology
thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJG Endocrinology
Chronic Pancreatitis
title Chronic Pancreatitis
title_full Chronic Pancreatitis
title_fullStr Chronic Pancreatitis
title_full_unstemmed Chronic Pancreatitis
title_short Chronic Pancreatitis
title_sort chronic pancreatitis
topic Hepatology
thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJG Endocrinology
topic_facet Hepatology
thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJG Endocrinology
url ONIX_20210420_9789535100119_924