Patch Clamp Technique

This book is a stimulating and interesting addition to the collected works on Patch clamp technique. Patch Clamping is an electrophysiological technique, which measures the electric current generated by a living cell, due to the movement of ions through the protein channels present in the cell membr...

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collection Directory of Open Access Books
description This book is a stimulating and interesting addition to the collected works on Patch clamp technique. Patch Clamping is an electrophysiological technique, which measures the electric current generated by a living cell, due to the movement of ions through the protein channels present in the cell membrane. The technique was developed by two German scientists, Erwin Neher and Bert Sakmann, who received the Nobel Prize in 1991 in Physiology for this innovative work. Patch clamp technique is used for measuring drug effect against a series of diseases and to find out the mechanism of diseases in animals and plants. It is also most useful in finding out the structure function activities of compounds and drugs, and most leading pharmaceutical companies used this technique for their drugs before bringing them for clinical trial. This book deals with the understanding of endogenous mechanisms of cells and their receptors as well as advantages of using this technique. It covers the basic principles and preparation types and also deals with the latest developments in the traditional patch clamp technique. Some chapters in this book take the technique to a next level of modulation and novel approach. This book will be of good value for students of physiology, neuroscience, cell biology and biophysics.
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spelling doab-20.500.12854ir-658722024-03-31T22:44:12Z Patch Clamp Technique Shad Kaneez, Fatima Cytology thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues::MBX History of medicine This book is a stimulating and interesting addition to the collected works on Patch clamp technique. Patch Clamping is an electrophysiological technique, which measures the electric current generated by a living cell, due to the movement of ions through the protein channels present in the cell membrane. The technique was developed by two German scientists, Erwin Neher and Bert Sakmann, who received the Nobel Prize in 1991 in Physiology for this innovative work. Patch clamp technique is used for measuring drug effect against a series of diseases and to find out the mechanism of diseases in animals and plants. It is also most useful in finding out the structure function activities of compounds and drugs, and most leading pharmaceutical companies used this technique for their drugs before bringing them for clinical trial. This book deals with the understanding of endogenous mechanisms of cells and their receptors as well as advantages of using this technique. It covers the basic principles and preparation types and also deals with the latest developments in the traditional patch clamp technique. Some chapters in this book take the technique to a next level of modulation and novel approach. This book will be of good value for students of physiology, neuroscience, cell biology and biophysics. 2021-04-20T15:28:09Z 2021-04-20T15:28:09Z 2012 book ONIX_20210420_9789535104063_1230 9789535104063 9789535152552 https://directory.doabooks.org/handle/20.500.12854/65872 eng image/jpeg n/a https://www.intechopen.com/books https://mts.intechopen.com/storage/books/1624/authors_book/authors_book.pdf IntechOpen IntechOpen 10.5772/2086 10.5772/2086 78a36484-2c0c-47cb-ad67-2b9f5cd4a8f6 9789535104063 9789535152552 IntechOpen 370 open access
spellingShingle Cytology
thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues::MBX History of medicine
Patch Clamp Technique
title Patch Clamp Technique
title_full Patch Clamp Technique
title_fullStr Patch Clamp Technique
title_full_unstemmed Patch Clamp Technique
title_short Patch Clamp Technique
title_sort patch clamp technique
topic Cytology
thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues::MBX History of medicine
topic_facet Cytology
thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues::MBX History of medicine
url ONIX_20210420_9789535104063_1230