Pancreatic Cancer
This book provides the reader with an overall understanding of the biology of pancreatic cancer, hereditary, complex signaling pathways and alternative therapies. The book explains nutrigenomics and epigenetics mechanisms such as DNA methylation, which may explain the etiology or progression of panc...
Zapisane w:
| Format: | Online |
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| Język: | angielski |
| Wydane: |
IntechOpen
2021
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| Hasła przedmiotowe: | |
| Dostęp online: | ONIX_20210420_9789535104100_1246 |
| Etykiety: |
Nie ma etykietki, Dołącz pierwszą etykiete!
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| _version_ | 1869529295830908928 |
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| collection | Directory of Open Access Books |
| description | This book provides the reader with an overall understanding of the biology of pancreatic cancer, hereditary, complex signaling pathways and alternative therapies. The book explains nutrigenomics and epigenetics mechanisms such as DNA methylation, which may explain the etiology or progression of pancreatic cancer. Book also summarizes the molecular control of oncogenic pathways such as K-Ras and KLF4. Since pancreatic cancer metastasizes to vital organs resulting in poor prognosis, special emphasis is given to the mechanism of tumor cell invasion and metastasis. Role of nitric oxide and Syk kinase in tumor metastasis is discussed in detail. Prevention strategies for pancreatic cancer are also described. The molecular mechanisms of the anti-cancer effects of curcumin, benzyl isothiocyante and vitamin D are discussed in detail. Furthermore, this book covers the basic mechanisms of resistance of pancreatic cancer to chemotherapy drugs such as gemcitabine and 5-flourouracil. |
| format | Online |
| id | doab-20.500.12854ir-65888 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | IntechOpen |
| publisherStr | IntechOpen |
| record_format | ojs |
| spelling | doab-20.500.12854ir-658882024-03-31T22:43:40Z Pancreatic Cancer Srivastava, Sanjay K. Oncology thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology This book provides the reader with an overall understanding of the biology of pancreatic cancer, hereditary, complex signaling pathways and alternative therapies. The book explains nutrigenomics and epigenetics mechanisms such as DNA methylation, which may explain the etiology or progression of pancreatic cancer. Book also summarizes the molecular control of oncogenic pathways such as K-Ras and KLF4. Since pancreatic cancer metastasizes to vital organs resulting in poor prognosis, special emphasis is given to the mechanism of tumor cell invasion and metastasis. Role of nitric oxide and Syk kinase in tumor metastasis is discussed in detail. Prevention strategies for pancreatic cancer are also described. The molecular mechanisms of the anti-cancer effects of curcumin, benzyl isothiocyante and vitamin D are discussed in detail. Furthermore, this book covers the basic mechanisms of resistance of pancreatic cancer to chemotherapy drugs such as gemcitabine and 5-flourouracil. 2021-04-20T15:28:32Z 2021-04-20T15:28:32Z 2012 book ONIX_20210420_9789535104100_1246 9789535104100 9789535169352 https://directory.doabooks.org/handle/20.500.12854/65888 eng image/jpeg n/a https://www.intechopen.com/books https://mts.intechopen.com/storage/books/763/authors_book/authors_book.pdf IntechOpen IntechOpen 10.5772/1271 10.5772/1271 78a36484-2c0c-47cb-ad67-2b9f5cd4a8f6 9789535104100 9789535169352 IntechOpen 446 open access |
| spellingShingle | Oncology thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology Pancreatic Cancer |
| title | Pancreatic Cancer |
| title_full | Pancreatic Cancer |
| title_fullStr | Pancreatic Cancer |
| title_full_unstemmed | Pancreatic Cancer |
| title_short | Pancreatic Cancer |
| title_sort | pancreatic cancer |
| topic | Oncology thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology |
| topic_facet | Oncology thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology |
| url | ONIX_20210420_9789535104100_1246 |