Gastrointestinal Stromal Tumor
Almost 30 years have gone by since the postulation that GISTs derive from mesenchymal stem elements, and only 15 years have gone by since the definitive detection of origin of GISTs. Research in the last decade was more focused upon the justification of imatinib mezylate therapy in GISTs and clarifi...
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| Materyal Türü: | Online |
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| Dil: | İngilizce |
| Baskı/Yayın Bilgisi: |
IntechOpen
2021
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| Konular: | |
| Online Erişim: | ONIX_20210420_9789535105800_1410 |
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| _version_ | 1869527020353880064 |
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| collection | Directory of Open Access Books |
| description | Almost 30 years have gone by since the postulation that GISTs derive from mesenchymal stem elements, and only 15 years have gone by since the definitive detection of origin of GISTs. Research in the last decade was more focused upon the justification of imatinib mezylate therapy in GISTs and clarification why a secondary resistance that occurred during the kinase inhibitors therapy. The era of therapy for GISTs, targeting the primary activating mutations in the KIT proto-oncogene; is being proclaimed as bringing the message of special importance to the pathologist role in multidisciplinary team that are responsible for treating patients with locally advanced or metastatic GIST. This is the first conclusive message forthcoming from this book. On the other hand, the book provides summarised and case-based knowledge on current management of gastrointestinal and extragastrointestinal stromal tumours. We hope that this book may be considered as a worthwhile timely addition to clinical science dissemination, medical education, further basic and clinical research. |
| format | Online |
| id | doab-20.500.12854ir-66052 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | IntechOpen |
| publisherStr | IntechOpen |
| record_format | ojs |
| spelling | doab-20.500.12854ir-660522024-03-31T22:43:37Z Gastrointestinal Stromal Tumor Lunevicius, Raimundas Oncology thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology Almost 30 years have gone by since the postulation that GISTs derive from mesenchymal stem elements, and only 15 years have gone by since the definitive detection of origin of GISTs. Research in the last decade was more focused upon the justification of imatinib mezylate therapy in GISTs and clarification why a secondary resistance that occurred during the kinase inhibitors therapy. The era of therapy for GISTs, targeting the primary activating mutations in the KIT proto-oncogene; is being proclaimed as bringing the message of special importance to the pathologist role in multidisciplinary team that are responsible for treating patients with locally advanced or metastatic GIST. This is the first conclusive message forthcoming from this book. On the other hand, the book provides summarised and case-based knowledge on current management of gastrointestinal and extragastrointestinal stromal tumours. We hope that this book may be considered as a worthwhile timely addition to clinical science dissemination, medical education, further basic and clinical research. 2021-04-20T15:32:50Z 2021-04-20T15:32:50Z 2012 book ONIX_20210420_9789535105800_1410 9789535105800 9789535169871 https://directory.doabooks.org/handle/20.500.12854/66052 eng image/jpeg n/a https://www.intechopen.com/books https://mts.intechopen.com/storage/books/1432/authors_book/authors_book.pdf IntechOpen IntechOpen 10.5772/1892 10.5772/1892 78a36484-2c0c-47cb-ad67-2b9f5cd4a8f6 9789535105800 9789535169871 IntechOpen 132 open access |
| spellingShingle | Oncology thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology Gastrointestinal Stromal Tumor |
| title | Gastrointestinal Stromal Tumor |
| title_full | Gastrointestinal Stromal Tumor |
| title_fullStr | Gastrointestinal Stromal Tumor |
| title_full_unstemmed | Gastrointestinal Stromal Tumor |
| title_short | Gastrointestinal Stromal Tumor |
| title_sort | gastrointestinal stromal tumor |
| topic | Oncology thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology |
| topic_facet | Oncology thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology |
| url | ONIX_20210420_9789535105800_1410 |