Liver Regeneration

Doctors and scientists have been aware of the "phenomenom" of liver regeneration since the time of the ancient Greeks, illustrated by the mythic tale of Prometheus' punishment. Nevertheless, true insight into its intricate mechanisms have only become available in the 20th century. Since then, the pa...

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Sprache:Englisch
Veröffentlicht: IntechOpen 2021
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collection Directory of Open Access Books
description Doctors and scientists have been aware of the "phenomenom" of liver regeneration since the time of the ancient Greeks, illustrated by the mythic tale of Prometheus' punishment. Nevertheless, true insight into its intricate mechanisms have only become available in the 20th century. Since then, the pathways and mechanisms involved in restoring the liver to its normal function after injury have been resolutely described and characterized, from the hepatic stem/progenitor cell activation and expansion to the more systemic mechanisms involving other tissues and organs like bone-marrow progenitor cell mobilization. This book describes some of the complex mechanisms involved in liver regeneration and provides examples of the most up-to-date strategies used to induce liver regeneration, both in the clinic and in the laboratory. The information presented will hopefully benefit not only professionals in the liver field, but also people in other areas of science (pharmacology, toxicology, etc) that wish to expand their knowledge of the fundamental biology that orchestrates liver injury and regeneration.
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spelling doab-20.500.12854ir-660932024-04-01T14:12:08Z Liver Regeneration Baptista, Pedro M. Biomedical engineering thema EDItEUR::M Medicine and Nursing::MQ Nursing and ancillary services::MQW Biomedical engineering Doctors and scientists have been aware of the "phenomenom" of liver regeneration since the time of the ancient Greeks, illustrated by the mythic tale of Prometheus' punishment. Nevertheless, true insight into its intricate mechanisms have only become available in the 20th century. Since then, the pathways and mechanisms involved in restoring the liver to its normal function after injury have been resolutely described and characterized, from the hepatic stem/progenitor cell activation and expansion to the more systemic mechanisms involving other tissues and organs like bone-marrow progenitor cell mobilization. This book describes some of the complex mechanisms involved in liver regeneration and provides examples of the most up-to-date strategies used to induce liver regeneration, both in the clinic and in the laboratory. The information presented will hopefully benefit not only professionals in the liver field, but also people in other areas of science (pharmacology, toxicology, etc) that wish to expand their knowledge of the fundamental biology that orchestrates liver injury and regeneration. 2021-04-20T15:33:55Z 2021-04-20T15:33:55Z 2012 book ONIX_20210420_9789535106227_1451 9789535106227 9789535170006 https://directory.doabooks.org/handle/20.500.12854/66093 eng image/jpeg n/a https://www.intechopen.com/books https://mts.intechopen.com/storage/books/1164/authors_book/authors_book.pdf IntechOpen IntechOpen 10.5772/1645 10.5772/1645 78a36484-2c0c-47cb-ad67-2b9f5cd4a8f6 9789535106227 9789535170006 IntechOpen 264 open access
spellingShingle Biomedical engineering
thema EDItEUR::M Medicine and Nursing::MQ Nursing and ancillary services::MQW Biomedical engineering
Liver Regeneration
title Liver Regeneration
title_full Liver Regeneration
title_fullStr Liver Regeneration
title_full_unstemmed Liver Regeneration
title_short Liver Regeneration
title_sort liver regeneration
topic Biomedical engineering
thema EDItEUR::M Medicine and Nursing::MQ Nursing and ancillary services::MQW Biomedical engineering
topic_facet Biomedical engineering
thema EDItEUR::M Medicine and Nursing::MQ Nursing and ancillary services::MQW Biomedical engineering
url ONIX_20210420_9789535106227_1451