Cell-Free Protein Synthesis
The Nobel Prize in Medicine 1968 for interpretation of the genetic code and its function in protein synthesis and in Chemistry 2009 for studies of the structure and function of the ribosome highlighted the ground-breaking experiment performed on May 15, 1961 by Nirenberg and Matthaei and their princ...
שמור ב:
| פורמט: | Online |
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| שפה: | אנגלית |
| יצא לאור: |
IntechOpen
2021
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| נושאים: | |
| גישה מקוונת: | ONIX_20210420_9789535108030_1597 |
| תגים: |
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| _version_ | 1869530959151366144 |
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| collection | Directory of Open Access Books |
| description | The Nobel Prize in Medicine 1968 for interpretation of the genetic code and its function in protein synthesis and in Chemistry 2009 for studies of the structure and function of the ribosome highlighted the ground-breaking experiment performed on May 15, 1961 by Nirenberg and Matthaei and their principal breakthrough on the creation of "cell-free protein synthesis (CFPS) system". Since then the continuous technical advances have revitalized CFPS system as a simple and powerful technology platform for industrial and high-throughput protein production. CFPS yields exceed grams protein per liter reaction volume and offer several advantages including the ability to easily manipulate the reaction components and conditions to favor protein synthesis, decreased sensitivity to product toxicity, batch reactions last for multiple hours, costs have been reduced orders of magnitude, and suitability for miniaturization and high-throughput applications. With these advantages, there is continuous increasing interest in CFPS system among biotechnologists, molecular biologists and medical or pharmacologists. |
| format | Online |
| id | doab-20.500.12854ir-66239 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | IntechOpen |
| publisherStr | IntechOpen |
| record_format | ojs |
| spelling | doab-20.500.12854ir-662392024-03-31T22:44:52Z Cell-Free Protein Synthesis Biyani, Manish Cytology thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues::MBX History of medicine The Nobel Prize in Medicine 1968 for interpretation of the genetic code and its function in protein synthesis and in Chemistry 2009 for studies of the structure and function of the ribosome highlighted the ground-breaking experiment performed on May 15, 1961 by Nirenberg and Matthaei and their principal breakthrough on the creation of "cell-free protein synthesis (CFPS) system". Since then the continuous technical advances have revitalized CFPS system as a simple and powerful technology platform for industrial and high-throughput protein production. CFPS yields exceed grams protein per liter reaction volume and offer several advantages including the ability to easily manipulate the reaction components and conditions to favor protein synthesis, decreased sensitivity to product toxicity, batch reactions last for multiple hours, costs have been reduced orders of magnitude, and suitability for miniaturization and high-throughput applications. With these advantages, there is continuous increasing interest in CFPS system among biotechnologists, molecular biologists and medical or pharmacologists. 2021-04-20T15:37:39Z 2021-04-20T15:37:39Z 2012 book ONIX_20210420_9789535108030_1597 9789535108030 9789535153283 https://directory.doabooks.org/handle/20.500.12854/66239 eng image/jpeg n/a https://www.intechopen.com/books https://mts.intechopen.com/storage/books/2580/authors_book/authors_book.pdf IntechOpen IntechOpen 10.5772/2955 10.5772/2955 78a36484-2c0c-47cb-ad67-2b9f5cd4a8f6 9789535108030 9789535153283 IntechOpen 146 open access |
| spellingShingle | Cytology thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues::MBX History of medicine Cell-Free Protein Synthesis |
| title | Cell-Free Protein Synthesis |
| title_full | Cell-Free Protein Synthesis |
| title_fullStr | Cell-Free Protein Synthesis |
| title_full_unstemmed | Cell-Free Protein Synthesis |
| title_short | Cell-Free Protein Synthesis |
| title_sort | cell free protein synthesis |
| topic | Cytology thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues::MBX History of medicine |
| topic_facet | Cytology thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues::MBX History of medicine |
| url | ONIX_20210420_9789535108030_1597 |