Pluripotent Stem Cells
Stem cells have generated a lot of excitement among the researchers, clinicians and the public alike. Various types of stem cells are being evaluated for their regenerative potential. Marginal benefit resulting by transplanting autologus stem cells (deemed to be absolutely safe) in various clinical...
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| Format: | Online |
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| Language: | English |
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IntechOpen
2021
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| Online Access: | ONIX_20210420_9789535111924_1951 |
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| description | Stem cells have generated a lot of excitement among the researchers, clinicians and the public alike. Various types of stem cells are being evaluated for their regenerative potential. Marginal benefit resulting by transplanting autologus stem cells (deemed to be absolutely safe) in various clinical conditions has been proposed to be a growth factor effect rather than true regeneration. In contrast, various pre-clinical studies have been undertaken, using differentiated cells from embryonic stem cells or induced pluripotent stem cells have shown promise, functional improvement and no signs of teratoma formation. The scientists are not in a rush to reach the clinic but a handful of clinical studies have shown promise. This book is a collection of studies/reviews, beginning with an introduction to the pluripotent stem cells and covering various aspects like derivation, differentiation, ethics, etc., and hence would provide insight into the recent standing on the pluripotent stem cells biology. The chapters have been categorized into three sections, covering subjects ranging from the generation of pluripotent stem cells and various means of their derivation from embryonic as well as adult tissues, the mechanistic understanding of pluripotency and narrating the potential therapeutic implications of these in vitro generated cells in various diseases, in addition to the associated pros and cons in the same. |
| format | Online |
| id | doab-20.500.12854ir-66592 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | IntechOpen |
| publisherStr | IntechOpen |
| record_format | ojs |
| spelling | doab-20.500.12854ir-665922024-04-05T17:30:52Z Pluripotent Stem Cells Bhartiya, Deepa Lenka, Nibedita Cellular biology (cytology) thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry Stem cells have generated a lot of excitement among the researchers, clinicians and the public alike. Various types of stem cells are being evaluated for their regenerative potential. Marginal benefit resulting by transplanting autologus stem cells (deemed to be absolutely safe) in various clinical conditions has been proposed to be a growth factor effect rather than true regeneration. In contrast, various pre-clinical studies have been undertaken, using differentiated cells from embryonic stem cells or induced pluripotent stem cells have shown promise, functional improvement and no signs of teratoma formation. The scientists are not in a rush to reach the clinic but a handful of clinical studies have shown promise. This book is a collection of studies/reviews, beginning with an introduction to the pluripotent stem cells and covering various aspects like derivation, differentiation, ethics, etc., and hence would provide insight into the recent standing on the pluripotent stem cells biology. The chapters have been categorized into three sections, covering subjects ranging from the generation of pluripotent stem cells and various means of their derivation from embryonic as well as adult tissues, the mechanistic understanding of pluripotency and narrating the potential therapeutic implications of these in vitro generated cells in various diseases, in addition to the associated pros and cons in the same. 2021-04-20T15:47:39Z 2021-04-20T15:47:39Z 2013 book ONIX_20210420_9789535111924_1951 9789535111924 9789535171782 https://directory.doabooks.org/handle/20.500.12854/66592 eng image/jpeg n/a https://www.intechopen.com/books https://mts.intechopen.com/storage/books/3263/authors_book/authors_book.pdf IntechOpen IntechOpen 10.5772/45917 10.5772/45917 78a36484-2c0c-47cb-ad67-2b9f5cd4a8f6 9789535111924 9789535171782 IntechOpen 640 open access |
| spellingShingle | Cellular biology (cytology) thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry Pluripotent Stem Cells |
| title | Pluripotent Stem Cells |
| title_full | Pluripotent Stem Cells |
| title_fullStr | Pluripotent Stem Cells |
| title_full_unstemmed | Pluripotent Stem Cells |
| title_short | Pluripotent Stem Cells |
| title_sort | pluripotent stem cells |
| topic | Cellular biology (cytology) thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry |
| topic_facet | Cellular biology (cytology) thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry |
| url | ONIX_20210420_9789535111924_1951 |