Adult Stem Cell Niches
Tissue-specific stem cells have the capacity to self-renew and differentiate into several types of functional cells that replenish lost cells throughout an organism?s lifetime. Studies on stem cells from diverse systems have shown that stem cell function is controlled by extracellular cues from the...
I tiakina i:
| Hōputu: | Online |
|---|---|
| Reo: | Ingarihi |
| I whakaputaina: |
IntechOpen
2021
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| Ngā marau: | |
| Urunga tuihono: | ONIX_20210420_9789535117186_2019 |
| Ngā Tūtohu: |
Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!
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| _version_ | 1869515677739515904 |
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| collection | Directory of Open Access Books |
| description | Tissue-specific stem cells have the capacity to self-renew and differentiate into several types of functional cells that replenish lost cells throughout an organism?s lifetime. Studies on stem cells from diverse systems have shown that stem cell function is controlled by extracellular cues from the niche and by intrinsic genetic programs within the stem cell. The objectives of this book would be to review the molecular mechanisms that mediate the balanced response of stem cells to the needs of the organisms. Likewise, niches have also been linked to pathologies, by imposing aberrant function on stem cells or other targets. Therefore, the second objective of this book would be to highligh the molecular dysregulation of niche biology leading to the disease. The third objective would be to review the therapeutical targets described within stem cell niches. |
| format | Online |
| id | doab-20.500.12854ir-66660 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | IntechOpen |
| publisherStr | IntechOpen |
| record_format | ojs |
| spelling | doab-20.500.12854ir-666602024-04-05T17:30:52Z Adult Stem Cell Niches Wislet-Gendebien, Sabine Cellular biology (cytology) thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry Tissue-specific stem cells have the capacity to self-renew and differentiate into several types of functional cells that replenish lost cells throughout an organism?s lifetime. Studies on stem cells from diverse systems have shown that stem cell function is controlled by extracellular cues from the niche and by intrinsic genetic programs within the stem cell. The objectives of this book would be to review the molecular mechanisms that mediate the balanced response of stem cells to the needs of the organisms. Likewise, niches have also been linked to pathologies, by imposing aberrant function on stem cells or other targets. Therefore, the second objective of this book would be to highligh the molecular dysregulation of niche biology leading to the disease. The third objective would be to review the therapeutical targets described within stem cell niches. 2021-04-20T15:49:54Z 2021-04-20T15:49:54Z 2014 book ONIX_20210420_9789535117186_2019 9789535117186 9789535172208 https://directory.doabooks.org/handle/20.500.12854/66660 eng image/jpeg n/a https://www.intechopen.com/books https://mts.intechopen.com/storage/books/3861/authors_book/authors_book.pdf IntechOpen IntechOpen 10.5772/57290 10.5772/57290 78a36484-2c0c-47cb-ad67-2b9f5cd4a8f6 9789535117186 9789535172208 IntechOpen 330 open access |
| spellingShingle | Cellular biology (cytology) thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry Adult Stem Cell Niches |
| title | Adult Stem Cell Niches |
| title_full | Adult Stem Cell Niches |
| title_fullStr | Adult Stem Cell Niches |
| title_full_unstemmed | Adult Stem Cell Niches |
| title_short | Adult Stem Cell Niches |
| title_sort | adult stem cell niches |
| topic | Cellular biology (cytology) thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry |
| topic_facet | Cellular biology (cytology) thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry |
| url | ONIX_20210420_9789535117186_2019 |