Anticoagulation Therapy
The available parenteral and oral anticoagulants have a large clinical use. Understanding biochemistry of anticoagulants may help to improve therapeutic strategies. Resistance to vitamin K antagonist drugs might be a problem for rodent populations. Patients who have thrombogenic risk factors should...
Spremljeno u:
| Format: | Online |
|---|---|
| Jezik: | engleski |
| Izdano: |
IntechOpen
2021
|
| Teme: | |
| Online pristup: | ONIX_20210420_9789535126676_2278 |
| Oznake: |
Bez oznaka, Budi prvi tko označuje ovaj zapis!
|
| Sažetak: | The available parenteral and oral anticoagulants have a large clinical use. Understanding biochemistry of anticoagulants may help to improve therapeutic strategies. Resistance to vitamin K antagonist drugs might be a problem for rodent populations. Patients who have thrombogenic risk factors should be anticoagulated. The need for cardiac implantable electronic devices is increasing, and there is a substantial number of patients who are on oral anticoagulant therapy. Prothrombin complex concentrate and other plasma concentrates are useful to deal with over-coagulated situations. The efficacy and safety of non-vitamin K antagonist oral anticoagulants have been proven in large phase III trials. The real-world data suggest even better outcomes with these agents compared to vitamin K antagonists. |
|---|