Receptors P1 and P2 as Targets for Drug Therapy in Humans
This book aims to provide a brief update on the functions of purinergic receptors in various systems, in addition to the signaling pathway activated to mediate these functions. We address the influence of hypoxia by modulating the activity of these receptors under physiological and pathophysiologica...
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| Format: | Online |
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| Langue: | anglais |
| Publié: |
IntechOpen
2021
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| Sujets: | |
| Accès en ligne: | ONIX_20210420_9781789845358_2708 |
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| _version_ | 1869520583267450880 |
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| collection | Directory of Open Access Books |
| description | This book aims to provide a brief update on the functions of purinergic receptors in various systems, in addition to the signaling pathway activated to mediate these functions. We address the influence of hypoxia by modulating the activity of these receptors under physiological and pathophysiological conditions. Additionally, we describe the mechanisms of induction of pain and inflammation in different systems. Finally, the book discusses some of the main bioinformatics tools currently used to improve or discover new prototypes capable of selectively acting on these receptors with estimated parameters of satisfactory solubility and toxicity for possible commercial implementation. |
| format | Online |
| id | doab-20.500.12854ir-67349 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | IntechOpen |
| publisherStr | IntechOpen |
| record_format | ojs |
| spelling | doab-20.500.12854ir-673492024-04-01T14:14:55Z Receptors P1 and P2 as Targets for Drug Therapy in Humans Faria, Robson Pharmacology thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKG Pharmacology This book aims to provide a brief update on the functions of purinergic receptors in various systems, in addition to the signaling pathway activated to mediate these functions. We address the influence of hypoxia by modulating the activity of these receptors under physiological and pathophysiological conditions. Additionally, we describe the mechanisms of induction of pain and inflammation in different systems. Finally, the book discusses some of the main bioinformatics tools currently used to improve or discover new prototypes capable of selectively acting on these receptors with estimated parameters of satisfactory solubility and toxicity for possible commercial implementation. 2021-04-20T16:11:08Z 2021-04-20T16:11:08Z 2020 book ONIX_20210420_9781789845358_2708 9781789845358 9781789845341 9781838800789 https://directory.doabooks.org/handle/20.500.12854/67349 eng image/jpeg n/a https://www.intechopen.com/books https://mts.intechopen.com/storage/books/8166/authors_book/authors_book.pdf IntechOpen IntechOpen 10.5772/intechopen.78115 10.5772/intechopen.78115 78a36484-2c0c-47cb-ad67-2b9f5cd4a8f6 9781789845358 9781789845341 9781838800789 IntechOpen 110 open access |
| spellingShingle | Pharmacology thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKG Pharmacology Receptors P1 and P2 as Targets for Drug Therapy in Humans |
| title | Receptors P1 and P2 as Targets for Drug Therapy in Humans |
| title_full | Receptors P1 and P2 as Targets for Drug Therapy in Humans |
| title_fullStr | Receptors P1 and P2 as Targets for Drug Therapy in Humans |
| title_full_unstemmed | Receptors P1 and P2 as Targets for Drug Therapy in Humans |
| title_short | Receptors P1 and P2 as Targets for Drug Therapy in Humans |
| title_sort | receptors p1 and p2 as targets for drug therapy in humans |
| topic | Pharmacology thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKG Pharmacology |
| topic_facet | Pharmacology thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKG Pharmacology |
| url | ONIX_20210420_9781789845358_2708 |