Quinazolinone and Quinazoline Derivatives
One of the problems with modern public health is target searching for new highly effective medicinal preparations. Among those medicinal preparations are the natural and synthetic origins of quinazolinone-4 derivatives. Quinazolinone derivatives are reported to be physiologically and pharmacological...
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| Formato: | Online |
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| Idioma: | inglês |
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IntechOpen
2021
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| Acesso em linha: | ONIX_20210420_9781838801403_2822 |
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| collection | Directory of Open Access Books |
| description | One of the problems with modern public health is target searching for new highly effective medicinal preparations. Among those medicinal preparations are the natural and synthetic origins of quinazolinone-4 derivatives. Quinazolinone derivatives are reported to be physiologically and pharmacologically active. They also exhibit a wide range of activities such as anticonvulsant, antiinflammatory, antifungal, antimalarial, and sedative properties. Some of these compounds are identified as drugs used as diuretics, vasodilators, and antihypertensive agents. Moreover, sulfonamide derivatives have been widely used as bacteriostatic agents. Prompted by the above-mentioned facts and in conjunction with our ongoing program on the utility of readily obtainable starting material for the synthesis of heterocyclic systems of biological interest, we have decided to synthesize a series of quinazolinone derivatives having sulfonamide moiety with a potentially wide spectrum of biological responses. |
| format | Online |
| id | doab-20.500.12854ir-67462 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | IntechOpen |
| publisherStr | IntechOpen |
| record_format | ojs |
| spelling | doab-20.500.12854ir-674622024-04-05T12:40:49Z Quinazolinone and Quinazoline Derivatives Gamal Al-kaf, Ali Organic chemistry thema EDItEUR::P Mathematics and Science::PN Chemistry::PNF Analytical chemistry::PNFS Spectrum analysis, spectrochemistry, mass spectrometry One of the problems with modern public health is target searching for new highly effective medicinal preparations. Among those medicinal preparations are the natural and synthetic origins of quinazolinone-4 derivatives. Quinazolinone derivatives are reported to be physiologically and pharmacologically active. They also exhibit a wide range of activities such as anticonvulsant, antiinflammatory, antifungal, antimalarial, and sedative properties. Some of these compounds are identified as drugs used as diuretics, vasodilators, and antihypertensive agents. Moreover, sulfonamide derivatives have been widely used as bacteriostatic agents. Prompted by the above-mentioned facts and in conjunction with our ongoing program on the utility of readily obtainable starting material for the synthesis of heterocyclic systems of biological interest, we have decided to synthesize a series of quinazolinone derivatives having sulfonamide moiety with a potentially wide spectrum of biological responses. 2021-04-20T16:14:53Z 2021-04-20T16:14:53Z 2020 book ONIX_20210420_9781838801403_2822 9781838801403 9781838801397 9781838800536 https://directory.doabooks.org/handle/20.500.12854/67462 eng image/jpeg n/a https://www.intechopen.com/books https://mts.intechopen.com/storage/books/9405/authors_book/authors_book.pdf IntechOpen IntechOpen 10.5772/intechopen.85315 10.5772/intechopen.85315 78a36484-2c0c-47cb-ad67-2b9f5cd4a8f6 9781838801403 9781838801397 9781838800536 IntechOpen 126 open access |
| spellingShingle | Organic chemistry thema EDItEUR::P Mathematics and Science::PN Chemistry::PNF Analytical chemistry::PNFS Spectrum analysis, spectrochemistry, mass spectrometry Quinazolinone and Quinazoline Derivatives |
| title | Quinazolinone and Quinazoline Derivatives |
| title_full | Quinazolinone and Quinazoline Derivatives |
| title_fullStr | Quinazolinone and Quinazoline Derivatives |
| title_full_unstemmed | Quinazolinone and Quinazoline Derivatives |
| title_short | Quinazolinone and Quinazoline Derivatives |
| title_sort | quinazolinone and quinazoline derivatives |
| topic | Organic chemistry thema EDItEUR::P Mathematics and Science::PN Chemistry::PNF Analytical chemistry::PNFS Spectrum analysis, spectrochemistry, mass spectrometry |
| topic_facet | Organic chemistry thema EDItEUR::P Mathematics and Science::PN Chemistry::PNF Analytical chemistry::PNFS Spectrum analysis, spectrochemistry, mass spectrometry |
| url | ONIX_20210420_9781838801403_2822 |