Sarcoidosis and Granulomatosis
Sarcoidosis is a multi-organ, granulomatous disease the etiology of which remains unknown. It is characterized by T-cell dysfunction and B-cell hyperactivity with increased local immune activity and inflammation that leads to the formation of noncaseating granulomas in the organs involved. The lung...
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| Format: | Online |
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| Language: | English |
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IntechOpen
2021
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| Online Access: | ONIX_20210420_9781839628337_2982 |
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| description | Sarcoidosis is a multi-organ, granulomatous disease the etiology of which remains unknown. It is characterized by T-cell dysfunction and B-cell hyperactivity with increased local immune activity and inflammation that leads to the formation of noncaseating granulomas in the organs involved. The lung and lymphatic system are the most commonly affected organs, however virtually any organ may be affected. Other common sites of involvement include the skin, eye, central nervous system, and the heart. Patients may present different symptoms related to the disease stage and the specific organ involved. Sarcoidosis is a global disease, and its prevalence has increased twofold over the past years. Due to the clinical heterogeneity and variable diagnostic criteria in different countries, it is difficult to calculate the exact prevalence and incidence of sarcoidosis. Age, sex, race, and geographic origin significantly influence the incidence of sarcoidosis. The book at hand seeks to assess the current diagnostic techniques, imaging techniques, differential diagnosis of this disease, as well as other granulomatous diseases mimicking sarcoidosis. |
| format | Online |
| id | doab-20.500.12854ir-67622 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | IntechOpen |
| publisherStr | IntechOpen |
| record_format | ojs |
| spelling | doab-20.500.12854ir-676222024-03-31T22:43:52Z Sarcoidosis and Granulomatosis Hosein Motamedi, Mohammad K. Immunology thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCM Immunology Sarcoidosis is a multi-organ, granulomatous disease the etiology of which remains unknown. It is characterized by T-cell dysfunction and B-cell hyperactivity with increased local immune activity and inflammation that leads to the formation of noncaseating granulomas in the organs involved. The lung and lymphatic system are the most commonly affected organs, however virtually any organ may be affected. Other common sites of involvement include the skin, eye, central nervous system, and the heart. Patients may present different symptoms related to the disease stage and the specific organ involved. Sarcoidosis is a global disease, and its prevalence has increased twofold over the past years. Due to the clinical heterogeneity and variable diagnostic criteria in different countries, it is difficult to calculate the exact prevalence and incidence of sarcoidosis. Age, sex, race, and geographic origin significantly influence the incidence of sarcoidosis. The book at hand seeks to assess the current diagnostic techniques, imaging techniques, differential diagnosis of this disease, as well as other granulomatous diseases mimicking sarcoidosis. 2021-04-20T16:20:04Z 2021-04-20T16:20:04Z 2020 book ONIX_20210420_9781839628337_2982 9781839628337 9781838810351 9781839628344 https://directory.doabooks.org/handle/20.500.12854/67622 eng image/jpeg n/a https://www.intechopen.com/books https://mts.intechopen.com/storage/books/7168/authors_book/authors_book.pdf IntechOpen IntechOpen 10.5772/intechopen.73968 10.5772/intechopen.73968 78a36484-2c0c-47cb-ad67-2b9f5cd4a8f6 9781839628337 9781838810351 9781839628344 IntechOpen 178 open access |
| spellingShingle | Immunology thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCM Immunology Sarcoidosis and Granulomatosis |
| title | Sarcoidosis and Granulomatosis |
| title_full | Sarcoidosis and Granulomatosis |
| title_fullStr | Sarcoidosis and Granulomatosis |
| title_full_unstemmed | Sarcoidosis and Granulomatosis |
| title_short | Sarcoidosis and Granulomatosis |
| title_sort | sarcoidosis and granulomatosis |
| topic | Immunology thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCM Immunology |
| topic_facet | Immunology thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCM Immunology |
| url | ONIX_20210420_9781839628337_2982 |