Glutathione System and Oxidative Stress in Health and Disease
The imbalance between the production of reactive oxygen species (ROS) and antioxidant defenses determines a state known as oxidative stress. Higher levels of pro-oxidants compared to antioxidant defenses may generate oxidative damage, which, in turn, may lead to modifications in cellular proteins, l...
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| Format: | Online |
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| Jezik: | engleski |
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IntechOpen
2021
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| Teme: | |
| Online pristup: | ONIX_20210420_9781838801267_2995 |
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| _version_ | 1869523220406730752 |
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| collection | Directory of Open Access Books |
| description | The imbalance between the production of reactive oxygen species (ROS) and antioxidant defenses determines a state known as oxidative stress. Higher levels of pro-oxidants compared to antioxidant defenses may generate oxidative damage, which, in turn, may lead to modifications in cellular proteins, lipids, and DNA, reducing functional capacity and increasing the risk of diseases. Nevertheless, the clearance of harmful reactive chemical species is achieved by the antioxidant defense systems. These protection systems are referred to as the first and second lines of defense and comprise the classic antioxidants, enzymatic and nonenzymatic defenses, including glutathione. This book presents and discusses the advancement of research on health and diseases and their underlying mechanisms, exploring mainly aspects related to the glutathione antioxidant system. |
| format | Online |
| id | doab-20.500.12854ir-67635 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | IntechOpen |
| publisherStr | IntechOpen |
| record_format | ojs |
| spelling | doab-20.500.12854ir-676352024-04-05T17:30:53Z Glutathione System and Oxidative Stress in Health and Disease Dulce Bagatini, Margarete Cellular biology (cytology) thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry The imbalance between the production of reactive oxygen species (ROS) and antioxidant defenses determines a state known as oxidative stress. Higher levels of pro-oxidants compared to antioxidant defenses may generate oxidative damage, which, in turn, may lead to modifications in cellular proteins, lipids, and DNA, reducing functional capacity and increasing the risk of diseases. Nevertheless, the clearance of harmful reactive chemical species is achieved by the antioxidant defense systems. These protection systems are referred to as the first and second lines of defense and comprise the classic antioxidants, enzymatic and nonenzymatic defenses, including glutathione. This book presents and discusses the advancement of research on health and diseases and their underlying mechanisms, exploring mainly aspects related to the glutathione antioxidant system. 2021-04-20T16:20:29Z 2021-04-20T16:20:29Z 2020 book ONIX_20210420_9781838801267_2995 2632-0983 9781838801267 9781838801250 9781839680182 https://directory.doabooks.org/handle/20.500.12854/67635 eng Biochemistry image/jpeg n/a https://www.intechopen.com/books https://mts.intechopen.com/storage/books/9002/authors_book/authors_book.pdf IntechOpen IntechOpen 10.5772/intechopen.82965 10.5772/intechopen.82965 78a36484-2c0c-47cb-ad67-2b9f5cd4a8f6 9781838801267 9781838801250 9781839680182 IntechOpen 17 138 open access |
| spellingShingle | Cellular biology (cytology) thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry Glutathione System and Oxidative Stress in Health and Disease |
| title | Glutathione System and Oxidative Stress in Health and Disease |
| title_full | Glutathione System and Oxidative Stress in Health and Disease |
| title_fullStr | Glutathione System and Oxidative Stress in Health and Disease |
| title_full_unstemmed | Glutathione System and Oxidative Stress in Health and Disease |
| title_short | Glutathione System and Oxidative Stress in Health and Disease |
| title_sort | glutathione system and oxidative stress in health and disease |
| topic | Cellular biology (cytology) thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry |
| topic_facet | Cellular biology (cytology) thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry |
| url | ONIX_20210420_9781838801267_2995 |