Aggregatibacter actinomycetemcomitans-Gram-Negative Bacterial Pathogen
Aggregatibacter actinomycetemcomitans is a well-studied Gram-negative bacterium that can often be found in the oral cavity of young individuals. It has several virulence factors and a large genetic diversity, which results in both harmless and highly virulent genotypes. To determine the virulence po...
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| Sprache: | Englisch |
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MDPI - Multidisciplinary Digital Publishing Institute
2021
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| Online-Zugang: | ONIX_20210501_9783039433766_63 |
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| description | Aggregatibacter actinomycetemcomitans is a well-studied Gram-negative bacterium that can often be found in the oral cavity of young individuals. It has several virulence factors and a large genetic diversity, which results in both harmless and highly virulent genotypes. To determine the virulence potential of the isolated bacteria, genetic profiling is recommended. Advanced knowledge of the virulence mechanisms induced by this bacterium is important for the development of future personalized preventive and treatment strategies. The fifteen papers in this book provide a strong and relevant background that can contribute to the improvement of future diagnosis and research strategies. |
| format | Online |
| id | doab-20.500.12854ir-68319 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-683192024-03-28T03:33:46Z Aggregatibacter actinomycetemcomitans-Gram-Negative Bacterial Pathogen Johansson, Anders DiRienzo, Joseph M. Aggregatibacter actinomycetemcomitans cagE virB1 virB4 genotype virulence mRNA assay quantitative ELISA cell lysis assay leukotoxin JP2 genotype cytolethal distending toxin lipopolysaccharides cytokine binding factors horizontal gene transfer outer membrane vesicles biofilm proteomic adherence endocarditis fimbriae JP2 periodontitis taxonomy core and accessory genes average nucleotide identity principal component analysis keratins organotypic gingival mucosa A. actinomycetemcomitans RNA-Seq genomic islands core genes accessory genes stress nutrient limitation differentially expressed genes. lymphocytes apoptosis RTX toxin localized aggressive periodontitis LFA-1 leukotoxin (LtxA) endocytosis n/a JP2 clone of Aggregatibacter actinomycetemcomitans JP2 in Caucasian microbiological diagnosis adjunctive antibiotics localized aggressive periodontitis: animal studies: human studies landscape ecology damage/response framework bacteremia horseshoe crab Origanum vulgare essential oil antimicrobial activity minimum inhibitory concentration minimal bactericidal concentration cytotoxicity leukotoxin neutralization inflammasome immune response periodontal disease proteomics thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences Aggregatibacter actinomycetemcomitans is a well-studied Gram-negative bacterium that can often be found in the oral cavity of young individuals. It has several virulence factors and a large genetic diversity, which results in both harmless and highly virulent genotypes. To determine the virulence potential of the isolated bacteria, genetic profiling is recommended. Advanced knowledge of the virulence mechanisms induced by this bacterium is important for the development of future personalized preventive and treatment strategies. The fifteen papers in this book provide a strong and relevant background that can contribute to the improvement of future diagnosis and research strategies. 2021-05-01T15:06:51Z 2021-05-01T15:06:51Z 2021 book ONIX_20210501_9783039433766_63 9783039433766 9783039433773 https://directory.doabooks.org/handle/20.500.12854/68319 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/3329 https://mdpi.com/books/pdfview/book/3329 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-03943-377-3 10.3390/books978-3-03943-377-3 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783039433766 9783039433773 232 Basel, Switzerland open access |
| spellingShingle | Aggregatibacter actinomycetemcomitans cagE virB1 virB4 genotype virulence mRNA assay quantitative ELISA cell lysis assay leukotoxin JP2 genotype cytolethal distending toxin lipopolysaccharides cytokine binding factors horizontal gene transfer outer membrane vesicles biofilm proteomic adherence endocarditis fimbriae JP2 periodontitis taxonomy core and accessory genes average nucleotide identity principal component analysis keratins organotypic gingival mucosa A. actinomycetemcomitans RNA-Seq genomic islands core genes accessory genes stress nutrient limitation differentially expressed genes. lymphocytes apoptosis RTX toxin localized aggressive periodontitis LFA-1 leukotoxin (LtxA) endocytosis n/a JP2 clone of Aggregatibacter actinomycetemcomitans JP2 in Caucasian microbiological diagnosis adjunctive antibiotics localized aggressive periodontitis: animal studies: human studies landscape ecology damage/response framework bacteremia horseshoe crab Origanum vulgare essential oil antimicrobial activity minimum inhibitory concentration minimal bactericidal concentration cytotoxicity leukotoxin neutralization inflammasome immune response periodontal disease proteomics thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences Aggregatibacter actinomycetemcomitans-Gram-Negative Bacterial Pathogen |
| title | Aggregatibacter actinomycetemcomitans-Gram-Negative Bacterial Pathogen |
| title_full | Aggregatibacter actinomycetemcomitans-Gram-Negative Bacterial Pathogen |
| title_fullStr | Aggregatibacter actinomycetemcomitans-Gram-Negative Bacterial Pathogen |
| title_full_unstemmed | Aggregatibacter actinomycetemcomitans-Gram-Negative Bacterial Pathogen |
| title_short | Aggregatibacter actinomycetemcomitans-Gram-Negative Bacterial Pathogen |
| title_sort | aggregatibacter actinomycetemcomitans gram negative bacterial pathogen |
| topic | Aggregatibacter actinomycetemcomitans cagE virB1 virB4 genotype virulence mRNA assay quantitative ELISA cell lysis assay leukotoxin JP2 genotype cytolethal distending toxin lipopolysaccharides cytokine binding factors horizontal gene transfer outer membrane vesicles biofilm proteomic adherence endocarditis fimbriae JP2 periodontitis taxonomy core and accessory genes average nucleotide identity principal component analysis keratins organotypic gingival mucosa A. actinomycetemcomitans RNA-Seq genomic islands core genes accessory genes stress nutrient limitation differentially expressed genes. lymphocytes apoptosis RTX toxin localized aggressive periodontitis LFA-1 leukotoxin (LtxA) endocytosis n/a JP2 clone of Aggregatibacter actinomycetemcomitans JP2 in Caucasian microbiological diagnosis adjunctive antibiotics localized aggressive periodontitis: animal studies: human studies landscape ecology damage/response framework bacteremia horseshoe crab Origanum vulgare essential oil antimicrobial activity minimum inhibitory concentration minimal bactericidal concentration cytotoxicity leukotoxin neutralization inflammasome immune response periodontal disease proteomics thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences |
| topic_facet | Aggregatibacter actinomycetemcomitans cagE virB1 virB4 genotype virulence mRNA assay quantitative ELISA cell lysis assay leukotoxin JP2 genotype cytolethal distending toxin lipopolysaccharides cytokine binding factors horizontal gene transfer outer membrane vesicles biofilm proteomic adherence endocarditis fimbriae JP2 periodontitis taxonomy core and accessory genes average nucleotide identity principal component analysis keratins organotypic gingival mucosa A. actinomycetemcomitans RNA-Seq genomic islands core genes accessory genes stress nutrient limitation differentially expressed genes. lymphocytes apoptosis RTX toxin localized aggressive periodontitis LFA-1 leukotoxin (LtxA) endocytosis n/a JP2 clone of Aggregatibacter actinomycetemcomitans JP2 in Caucasian microbiological diagnosis adjunctive antibiotics localized aggressive periodontitis: animal studies: human studies landscape ecology damage/response framework bacteremia horseshoe crab Origanum vulgare essential oil antimicrobial activity minimum inhibitory concentration minimal bactericidal concentration cytotoxicity leukotoxin neutralization inflammasome immune response periodontal disease proteomics thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences |
| url | ONIX_20210501_9783039433766_63 |