Mathematical Modelling in Biomedicine

Mathematical modelling in biomedicine is a rapidly developing scientific discipline at the intersection of medicine, biology, mathematics, physics, and computer science. Its progress is stimulated by fundamental scientific questions and by the applications to public health. This book represents a co...

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Argitaratua: MDPI - Multidisciplinary Digital Publishing Institute 2021
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collection Directory of Open Access Books
description Mathematical modelling in biomedicine is a rapidly developing scientific discipline at the intersection of medicine, biology, mathematics, physics, and computer science. Its progress is stimulated by fundamental scientific questions and by the applications to public health. This book represents a collection of papers devoted to mathematical modelling of various physiological problems in normal and pathological conditions. It covers a broad range of topics including cardiovascular system and diseases, heart and brain modelling, tumor growth, viral infections, and immune response. Computational models of blood circulation are used to study the influence of heart arrhythmias on coronary blood flow and on operating modes for left-ventricle-assisted devices. Wave propagation in the cardiac tissue is investigated in order to show the influence of tissue heterogeneity and fibrosis. The models of tumor growth are used to determine optimal protocols of antiangiogenic and radiotherapy. The models of viral hepatitis kinetics are considered for the parameter identification, and the evolution of viral quasi-species is investigated. The book presents the state-of-the-art in mathematical modelling in biomedicine and opens new perspectives in this passionate field of research.
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language eng
publishDate 2021
publishDateRange 2021
publishDateSort 2021
publisher MDPI - Multidisciplinary Digital Publishing Institute
publisherStr MDPI - Multidisciplinary Digital Publishing Institute
record_format ojs
spelling doab-20.500.12854ir-683372024-03-28T03:32:21Z Mathematical Modelling in Biomedicine Volpert, Vitaly virus density distribution genotype virus infection immune response resistance to treatment nonlocal interaction quasi-species diversification mathematical oncology spatially distributed modeling reaction-diffusion-convection equations computer experiment spiral wave heterogeneity heart modeling myocardium left ventricle neural field model integro-differential equation waves brain stimulation mathematical modeling cardiac mechanics multiscale simulation cardiomyopathies left ventricle remodeling spatially-distributed modeling gradient descent 1D haemodynamics systole variations coronary circulation cardiac pacing tachycardia bradycardia interventricular asynchrony long QT syndrome premature ventricular contraction rotary blood pump lumped heart model cardiac fibrosis excitable media wave break elongated obstacle lymph flow mathematical modelling lymphatic vessels lymph nodes parameter estimation constrained optimization derivative free optimization multiscale models differential equations viral hepatitis thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science Mathematical modelling in biomedicine is a rapidly developing scientific discipline at the intersection of medicine, biology, mathematics, physics, and computer science. Its progress is stimulated by fundamental scientific questions and by the applications to public health. This book represents a collection of papers devoted to mathematical modelling of various physiological problems in normal and pathological conditions. It covers a broad range of topics including cardiovascular system and diseases, heart and brain modelling, tumor growth, viral infections, and immune response. Computational models of blood circulation are used to study the influence of heart arrhythmias on coronary blood flow and on operating modes for left-ventricle-assisted devices. Wave propagation in the cardiac tissue is investigated in order to show the influence of tissue heterogeneity and fibrosis. The models of tumor growth are used to determine optimal protocols of antiangiogenic and radiotherapy. The models of viral hepatitis kinetics are considered for the parameter identification, and the evolution of viral quasi-species is investigated. The book presents the state-of-the-art in mathematical modelling in biomedicine and opens new perspectives in this passionate field of research. 2021-05-01T15:07:12Z 2021-05-01T15:07:12Z 2021 book ONIX_20210501_9783039434930_81 9783039434930 9783039434947 https://directory.doabooks.org/handle/20.500.12854/68337 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/3347 https://mdpi.com/books/pdfview/book/3347 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-03943-494-7 10.3390/books978-3-03943-494-7 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783039434930 9783039434947 224 Basel, Switzerland open access
spellingShingle virus density distribution
genotype
virus infection
immune response
resistance to treatment
nonlocal interaction
quasi-species diversification
mathematical oncology
spatially distributed modeling
reaction-diffusion-convection equations
computer experiment
spiral wave
heterogeneity
heart modeling
myocardium
left ventricle
neural field model
integro-differential equation
waves
brain stimulation
mathematical modeling
cardiac mechanics
multiscale simulation
cardiomyopathies
left ventricle remodeling
spatially-distributed modeling
gradient descent
1D haemodynamics
systole variations
coronary circulation
cardiac pacing
tachycardia
bradycardia
interventricular asynchrony
long QT syndrome
premature ventricular contraction
rotary blood pump
lumped heart model
cardiac fibrosis
excitable media
wave break
elongated obstacle
lymph flow
mathematical modelling
lymphatic vessels
lymph nodes
parameter estimation
constrained optimization
derivative free optimization
multiscale models
differential equations
viral hepatitis
thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::P Mathematics and Science
Mathematical Modelling in Biomedicine
title Mathematical Modelling in Biomedicine
title_full Mathematical Modelling in Biomedicine
title_fullStr Mathematical Modelling in Biomedicine
title_full_unstemmed Mathematical Modelling in Biomedicine
title_short Mathematical Modelling in Biomedicine
title_sort mathematical modelling in biomedicine
topic virus density distribution
genotype
virus infection
immune response
resistance to treatment
nonlocal interaction
quasi-species diversification
mathematical oncology
spatially distributed modeling
reaction-diffusion-convection equations
computer experiment
spiral wave
heterogeneity
heart modeling
myocardium
left ventricle
neural field model
integro-differential equation
waves
brain stimulation
mathematical modeling
cardiac mechanics
multiscale simulation
cardiomyopathies
left ventricle remodeling
spatially-distributed modeling
gradient descent
1D haemodynamics
systole variations
coronary circulation
cardiac pacing
tachycardia
bradycardia
interventricular asynchrony
long QT syndrome
premature ventricular contraction
rotary blood pump
lumped heart model
cardiac fibrosis
excitable media
wave break
elongated obstacle
lymph flow
mathematical modelling
lymphatic vessels
lymph nodes
parameter estimation
constrained optimization
derivative free optimization
multiscale models
differential equations
viral hepatitis
thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::P Mathematics and Science
topic_facet virus density distribution
genotype
virus infection
immune response
resistance to treatment
nonlocal interaction
quasi-species diversification
mathematical oncology
spatially distributed modeling
reaction-diffusion-convection equations
computer experiment
spiral wave
heterogeneity
heart modeling
myocardium
left ventricle
neural field model
integro-differential equation
waves
brain stimulation
mathematical modeling
cardiac mechanics
multiscale simulation
cardiomyopathies
left ventricle remodeling
spatially-distributed modeling
gradient descent
1D haemodynamics
systole variations
coronary circulation
cardiac pacing
tachycardia
bradycardia
interventricular asynchrony
long QT syndrome
premature ventricular contraction
rotary blood pump
lumped heart model
cardiac fibrosis
excitable media
wave break
elongated obstacle
lymph flow
mathematical modelling
lymphatic vessels
lymph nodes
parameter estimation
constrained optimization
derivative free optimization
multiscale models
differential equations
viral hepatitis
thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::P Mathematics and Science
url ONIX_20210501_9783039434930_81