Diagnosis and Treatment of Small Bowel Disorders
Over the last few decades, remarkable progress has been made in understanding the aetiology and pathophysiology of diseases and many new theories emphasize the importance of the small bowel ‘ecosystem’ in the pathogenesis of acute and chronic illness. Emerging factors such as microbiome, stem cells,...
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| Định dạng: | Online |
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| Ngôn ngữ: | Tiếng Anh |
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MDPI - Multidisciplinary Digital Publishing Institute
2021
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| Những chủ đề: | |
| Truy cập trực tuyến: | ONIX_20210501_9783039438730_87 |
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| _version_ | 1869520011095179264 |
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| collection | Directory of Open Access Books |
| description | Over the last few decades, remarkable progress has been made in understanding the aetiology and pathophysiology of diseases and many new theories emphasize the importance of the small bowel ‘ecosystem’ in the pathogenesis of acute and chronic illness. Emerging factors such as microbiome, stem cells, innate intestinal immunity and the enteric nervous system along with mucosal and endothelial barriers have key role in the development of gastrointestinal and extra-intestinal diseases. Therefore, the small intestine is considered key player in metabolic disease development, including diabetes mellitus, and other diet-related disorders such as celiac and non-celiac enteropathies. Another major field is drug metabolism and its interaction with microbiota. Moreover, the emergence of gut-brain, gut-liver and gut-blood barriers points toward the important role of small intestine in the pathogenesis of common disorders, such as liver disease, hypertension and neurodegenerative disease. However, the small bowel remains an organ that is difficult to fully access and assess and accurate diagnosis often poses a clinical challenge. Eventually, the therapeutic potential remains untapped. Therefore, it is due time to direct our interest towards the small intestine and unravel the interplay between small-bowel and other gastrointestinal (GI) and non-GI related maladies. |
| format | Online |
| id | doab-20.500.12854ir-68343 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-683432024-03-28T03:33:28Z Diagnosis and Treatment of Small Bowel Disorders Koulaouzidis, Anastasios Marlicz, Wojciech capsule endoscopy Crohn’s disease mucosal healing small bowel gut brain axis microbiota functional gastrointestinal disorders inflammatory bowel disease (IBD) adult stem cells surgical site infections (SSIs) probiotics prebiotics synbiotics surgery adverse events meta-analysis systematic review hyperspectral imaging multispectral imaging clinical diagnosis biomedical optical imaging gastroenterology medical diagnostic imaging small-bowel mass small-bowel bulge video capsule endoscopy cystic fibrosis gut microbiota intestinal inflammation fecal calprotectin dysbiosis index celiac disease biomarker serology enteropathy n/a colon cancer cancer risk collagenous colitis lung cancer microscopic colitis skin cancer squamous cell carcinoma thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences Over the last few decades, remarkable progress has been made in understanding the aetiology and pathophysiology of diseases and many new theories emphasize the importance of the small bowel ‘ecosystem’ in the pathogenesis of acute and chronic illness. Emerging factors such as microbiome, stem cells, innate intestinal immunity and the enteric nervous system along with mucosal and endothelial barriers have key role in the development of gastrointestinal and extra-intestinal diseases. Therefore, the small intestine is considered key player in metabolic disease development, including diabetes mellitus, and other diet-related disorders such as celiac and non-celiac enteropathies. Another major field is drug metabolism and its interaction with microbiota. Moreover, the emergence of gut-brain, gut-liver and gut-blood barriers points toward the important role of small intestine in the pathogenesis of common disorders, such as liver disease, hypertension and neurodegenerative disease. However, the small bowel remains an organ that is difficult to fully access and assess and accurate diagnosis often poses a clinical challenge. Eventually, the therapeutic potential remains untapped. Therefore, it is due time to direct our interest towards the small intestine and unravel the interplay between small-bowel and other gastrointestinal (GI) and non-GI related maladies. 2021-05-01T15:07:19Z 2021-05-01T15:07:19Z 2021 book ONIX_20210501_9783039438730_87 9783039438730 9783039438747 https://directory.doabooks.org/handle/20.500.12854/68343 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/3353 https://mdpi.com/books/pdfview/book/3353 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-03943-874-7 10.3390/books978-3-03943-874-7 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783039438730 9783039438747 146 Basel, Switzerland open access |
| spellingShingle | capsule endoscopy Crohn’s disease mucosal healing small bowel gut brain axis microbiota functional gastrointestinal disorders inflammatory bowel disease (IBD) adult stem cells surgical site infections (SSIs) probiotics prebiotics synbiotics surgery adverse events meta-analysis systematic review hyperspectral imaging multispectral imaging clinical diagnosis biomedical optical imaging gastroenterology medical diagnostic imaging small-bowel mass small-bowel bulge video capsule endoscopy cystic fibrosis gut microbiota intestinal inflammation fecal calprotectin dysbiosis index celiac disease biomarker serology enteropathy n/a colon cancer cancer risk collagenous colitis lung cancer microscopic colitis skin cancer squamous cell carcinoma thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences Diagnosis and Treatment of Small Bowel Disorders |
| title | Diagnosis and Treatment of Small Bowel Disorders |
| title_full | Diagnosis and Treatment of Small Bowel Disorders |
| title_fullStr | Diagnosis and Treatment of Small Bowel Disorders |
| title_full_unstemmed | Diagnosis and Treatment of Small Bowel Disorders |
| title_short | Diagnosis and Treatment of Small Bowel Disorders |
| title_sort | diagnosis and treatment of small bowel disorders |
| topic | capsule endoscopy Crohn’s disease mucosal healing small bowel gut brain axis microbiota functional gastrointestinal disorders inflammatory bowel disease (IBD) adult stem cells surgical site infections (SSIs) probiotics prebiotics synbiotics surgery adverse events meta-analysis systematic review hyperspectral imaging multispectral imaging clinical diagnosis biomedical optical imaging gastroenterology medical diagnostic imaging small-bowel mass small-bowel bulge video capsule endoscopy cystic fibrosis gut microbiota intestinal inflammation fecal calprotectin dysbiosis index celiac disease biomarker serology enteropathy n/a colon cancer cancer risk collagenous colitis lung cancer microscopic colitis skin cancer squamous cell carcinoma thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences |
| topic_facet | capsule endoscopy Crohn’s disease mucosal healing small bowel gut brain axis microbiota functional gastrointestinal disorders inflammatory bowel disease (IBD) adult stem cells surgical site infections (SSIs) probiotics prebiotics synbiotics surgery adverse events meta-analysis systematic review hyperspectral imaging multispectral imaging clinical diagnosis biomedical optical imaging gastroenterology medical diagnostic imaging small-bowel mass small-bowel bulge video capsule endoscopy cystic fibrosis gut microbiota intestinal inflammation fecal calprotectin dysbiosis index celiac disease biomarker serology enteropathy n/a colon cancer cancer risk collagenous colitis lung cancer microscopic colitis skin cancer squamous cell carcinoma thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences |
| url | ONIX_20210501_9783039438730_87 |