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Novel Biomarkers in Alzheimer's Disease

Alzheimer’s disease (AD) represents the most common form of dementia in the elderly population worldwide. AD is characterized by progressive neurodegeneration that leads to a gradual deterioration of memory and other cognitive functions. Given the global prevalence and impact of AD, there is a criti...

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Gardado en:
Formato: Online
Idioma:inglés
Publicado: MDPI - Multidisciplinary Digital Publishing Institute 2021
Subjects:
flotillin
Alzheimer’s disease
biomarker
exosomes
beta-amyloid
Tau
aging
biomarkers
cytokines
cognitive decline
metabolomics
neuroinflammation
multivariate analysis
physical performance
person-tailored
PET/CT
(18F)FDG
neuropsychological assessment
APP mutations
APOE alleles
PSEN1
PSEN2
germline mutations
late onset AD
early onset AD
familial AD
genetics of AD
mitochondrial spare respiratory capacity
mitochondrial
membrane potential
glycolytic reserve
semantic memory
phonemic fluency
episodic memory
neuropsychology
neuroimaging
Alzheimer's disease
mild cognitive impairment
EEG
TMS
obesity
diabetes
inflammation
Amyloid Beta
mitochondrial dysfunction
nutrition
omega-3 fatty acids
antioxidant
carotenoids
vitamin E
cognition
older adults
ageing
subjective cognitive decline
clock genes
Clock
ApoE
cardiovascular risk factors
Alzheimer disease
semantic priming
amyloid beta
cerebrospinal fluid
amyloid beta peptide
total tau
phosphorylated tau
diagnosis
drug development
clinical trials
diagnostic research
virus
bacteria
dementia
blood
behavioral and psychological symptoms of dementia (BPSD)
Alzheimer’s disease (AD)
neuropsychiatry inventory scale (NPI)
endophenotypes
CART analysis
MTHFR
APOE
COMT
genetic variants
early diagnosis
biofluids
amyloid cascade hypothesis
glucose metabolism
adipose tissue dysfunction
energetic metabolism
lysosomes dysfunction
Type-3-Diabetes
neurodegeneration
amyloid
tau
soluble TREM2
NfL
Multiplex
SiMoA
diagnostics
messenger RNA
microRNA
neurotropic microbes
precision medicine
prognostics
synaptic biomarkers
neurofilament light chain
n/a
thema EDItEUR::M Medicine and Nursing
Acceso en liña:ONIX_20210501_9783039439034_107
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Summary:Alzheimer’s disease (AD) represents the most common form of dementia in the elderly population worldwide. AD is characterized by progressive neurodegeneration that leads to a gradual deterioration of memory and other cognitive functions. Given the global prevalence and impact of AD, there is a critical need to establish biomarkers that can be used to detect AD in individuals before the onset of clinical signs and provide mitigating therapeutics. The aim of this Special Issue is to discuss the current knowledge as well as future perspectives on the role of biomarkers in the screening, diagnosis, treatment and follow-up of AD.

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