Cannabis
Over the years, there has been increasing interest into the public health impact of cannabis use, especially by young adults. This follows the evidence of a growing prevalence of regular cannabis use worldwide, with approximately 200 million users. Recreational cannabis use, especially a frequent us...
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| Format: | Online |
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| Sprog: | engelsk |
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MDPI - Multidisciplinary Digital Publishing Institute
2021
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| Online adgang: | ONIX_20210501_9783039439959_108 |
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| _version_ | 1869528163646701568 |
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| collection | Directory of Open Access Books |
| description | Over the years, there has been increasing interest into the public health impact of cannabis use, especially by young adults. This follows the evidence of a growing prevalence of regular cannabis use worldwide, with approximately 200 million users. Recreational cannabis use, especially a frequent use of products with high levels of its main psychoactive ingredient delta-9-tetrahydrocannabinol (Δ 9-THC), can cause dependence and have transient and long-lasting detrimental mental health effects, also negatively impacting cognitive processing and brain function and metabolism. In regular users, the development of tolerance to some of the effects of cannabis, especially the pleasurable ones, may lead to progressively heavier use in order to obtain the same effects in terms of their intensity, with higher health risks. However, the Cannabis Sativa plant contains different chemicals with different potential effects. In this regard, cannabidiol has gained interest because of its potential therapeutic properties, in line with evidence that CBD and Δ9-THC may exhibit opposite effects at the cannabinoid receptor type 1 (CB1), Δ9-THC being a partial agonist and CBD an antagonist/inverse agonist. Different cannabinoids may modulate human brain function and behavior in different ways, with different risk–benefit profiles. |
| format | Online |
| id | doab-20.500.12854ir-68363 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-683632024-03-31T13:08:32Z Cannabis Colizzi, Marco Bhattacharyya, Sagnik delta-9-tetrahydrocannabinol placebo cannabis-associated psychosis schizophrenia BDNF CB1 CB2 episodic memory exercise African American black older adult marijuana use cannabis use disorder cue reactivity craving inhibitory control frontal alpha asymmetry EEG cannabinoids cannabis use psychotic disorder genetics age of onset clinical high risk cannabis memory functional magnetic resonance imaging THC systematic review gyrification surface area cortical surface structure aerobic fitness gender endocannabinoid system executive functions problematic cannabis use triple network EEG functional connectivity eLORETA resting state Delta-9-tetrahydrocannabinol dronabinol marijuana randomized controlled trial opioids traumatic injury alcohol adolescents fMRI interoception negative reinforcement migraine: chronic pain triptans disability n/a thema EDItEUR::M Medicine and Nursing thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences Over the years, there has been increasing interest into the public health impact of cannabis use, especially by young adults. This follows the evidence of a growing prevalence of regular cannabis use worldwide, with approximately 200 million users. Recreational cannabis use, especially a frequent use of products with high levels of its main psychoactive ingredient delta-9-tetrahydrocannabinol (Δ 9-THC), can cause dependence and have transient and long-lasting detrimental mental health effects, also negatively impacting cognitive processing and brain function and metabolism. In regular users, the development of tolerance to some of the effects of cannabis, especially the pleasurable ones, may lead to progressively heavier use in order to obtain the same effects in terms of their intensity, with higher health risks. However, the Cannabis Sativa plant contains different chemicals with different potential effects. In this regard, cannabidiol has gained interest because of its potential therapeutic properties, in line with evidence that CBD and Δ9-THC may exhibit opposite effects at the cannabinoid receptor type 1 (CB1), Δ9-THC being a partial agonist and CBD an antagonist/inverse agonist. Different cannabinoids may modulate human brain function and behavior in different ways, with different risk–benefit profiles. 2021-05-01T15:08:10Z 2021-05-01T15:08:10Z 2021 book ONIX_20210501_9783039439959_108 9783039439959 9783039439966 https://directory.doabooks.org/handle/20.500.12854/68363 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/3372 https://mdpi.com/books/pdfview/book/3372 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-03943-996-6 10.3390/books978-3-03943-996-6 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783039439959 9783039439966 204 Basel, Switzerland open access |
| spellingShingle | delta-9-tetrahydrocannabinol placebo cannabis-associated psychosis schizophrenia BDNF CB1 CB2 episodic memory exercise African American black older adult marijuana use cannabis use disorder cue reactivity craving inhibitory control frontal alpha asymmetry EEG cannabinoids cannabis use psychotic disorder genetics age of onset clinical high risk cannabis memory functional magnetic resonance imaging THC systematic review gyrification surface area cortical surface structure aerobic fitness gender endocannabinoid system executive functions problematic cannabis use triple network EEG functional connectivity eLORETA resting state Delta-9-tetrahydrocannabinol dronabinol marijuana randomized controlled trial opioids traumatic injury alcohol adolescents fMRI interoception negative reinforcement migraine: chronic pain triptans disability n/a thema EDItEUR::M Medicine and Nursing thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences Cannabis |
| title | Cannabis |
| title_full | Cannabis |
| title_fullStr | Cannabis |
| title_full_unstemmed | Cannabis |
| title_short | Cannabis |
| title_sort | cannabis |
| topic | delta-9-tetrahydrocannabinol placebo cannabis-associated psychosis schizophrenia BDNF CB1 CB2 episodic memory exercise African American black older adult marijuana use cannabis use disorder cue reactivity craving inhibitory control frontal alpha asymmetry EEG cannabinoids cannabis use psychotic disorder genetics age of onset clinical high risk cannabis memory functional magnetic resonance imaging THC systematic review gyrification surface area cortical surface structure aerobic fitness gender endocannabinoid system executive functions problematic cannabis use triple network EEG functional connectivity eLORETA resting state Delta-9-tetrahydrocannabinol dronabinol marijuana randomized controlled trial opioids traumatic injury alcohol adolescents fMRI interoception negative reinforcement migraine: chronic pain triptans disability n/a thema EDItEUR::M Medicine and Nursing thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences |
| topic_facet | delta-9-tetrahydrocannabinol placebo cannabis-associated psychosis schizophrenia BDNF CB1 CB2 episodic memory exercise African American black older adult marijuana use cannabis use disorder cue reactivity craving inhibitory control frontal alpha asymmetry EEG cannabinoids cannabis use psychotic disorder genetics age of onset clinical high risk cannabis memory functional magnetic resonance imaging THC systematic review gyrification surface area cortical surface structure aerobic fitness gender endocannabinoid system executive functions problematic cannabis use triple network EEG functional connectivity eLORETA resting state Delta-9-tetrahydrocannabinol dronabinol marijuana randomized controlled trial opioids traumatic injury alcohol adolescents fMRI interoception negative reinforcement migraine: chronic pain triptans disability n/a thema EDItEUR::M Medicine and Nursing thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences |
| url | ONIX_20210501_9783039439959_108 |