Oxidative Stress in Diabetic Retinopathy

The combination of an increasing prevalence of diabetes and the aging of populations enables the appearance of a greater number of associated complications such as diabetic retinopathy. Diabetic retinopathy is the leading cause of preventable vision loss in working-age adults. The objective of this...

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collection Directory of Open Access Books
description The combination of an increasing prevalence of diabetes and the aging of populations enables the appearance of a greater number of associated complications such as diabetic retinopathy. Diabetic retinopathy is the leading cause of preventable vision loss in working-age adults. The objective of this Special Issue is to highlight the existing evidence regarding the relationship between oxidative stress and low-grade chronic inflammation induced by hyperglycemia with the development and progression of diabetic retinopathy, with an emphasis on the importance of early diagnosis and the use of antioxidant and anti-inflammatory approaches to prevent or delay the harmful effects of diabetes on retinal tissue.
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publishDate 2021
publishDateRange 2021
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publisherStr MDPI - Multidisciplinary Digital Publishing Institute
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spelling doab-20.500.12854ir-684532024-03-30T23:23:03Z Oxidative Stress in Diabetic Retinopathy Ortega, Ángel Luis eicosanoids oxidative stress diabetic retinopathy cyclooxygenase lipoxygenase Cytochrome P450 HDAC6 tubastatin A retinal endothelial cells retinal endothelial cell senescence db/db mice Cinnamomi Ramulus Paeoniae Radix CPA4-1 blood-retinal barrier occludin human retina epiretinal membrane internal limiting membrane vitreoretinal surgery macular hole proliferative diabetic retinopathy antioxidants diabetes mellitus free radicals high-mobility group box 1 (HMGB1) inflammatory pathways novel therapies diabetic retinopathy (DR) inflammation angiogenesis extracellular vesicles miRNA biomarkers apoptosis fenofibrate thioredoxin hyperglycemia astaxanthin carotenoid reactive oxygen species photoreceptor cells PI3K Nrf2 eicosapentaenoic acid (EPA) docosahexaenoic acid (DHA) retinal pigment epithelium antioxidant ascorbic acid retinal disease vitamin D GLP-1 superoxide dismutase biomarkers of diabetic retinopathy metabolic memory tear film aqueous humor vitreous humor mitochondria redox photoreceptor glycation aging glyoxalase n/a thema EDItEUR::M Medicine and Nursing The combination of an increasing prevalence of diabetes and the aging of populations enables the appearance of a greater number of associated complications such as diabetic retinopathy. Diabetic retinopathy is the leading cause of preventable vision loss in working-age adults. The objective of this Special Issue is to highlight the existing evidence regarding the relationship between oxidative stress and low-grade chronic inflammation induced by hyperglycemia with the development and progression of diabetic retinopathy, with an emphasis on the importance of early diagnosis and the use of antioxidant and anti-inflammatory approaches to prevent or delay the harmful effects of diabetes on retinal tissue. 2021-05-01T15:09:59Z 2021-05-01T15:09:59Z 2021 book ONIX_20210501_9783036504483_199 9783036504483 9783036504490 https://directory.doabooks.org/handle/20.500.12854/68453 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/3470 https://mdpi.com/books/pdfview/book/3470 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-0449-0 10.3390/books978-3-0365-0449-0 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036504483 9783036504490 322 Basel, Switzerland open access
spellingShingle eicosanoids
oxidative stress
diabetic retinopathy
cyclooxygenase
lipoxygenase
Cytochrome P450
HDAC6
tubastatin A
retinal endothelial cells
retinal endothelial cell senescence
db/db mice
Cinnamomi Ramulus
Paeoniae Radix
CPA4-1
blood-retinal barrier
occludin
human retina
epiretinal membrane
internal limiting membrane
vitreoretinal surgery
macular hole
proliferative diabetic retinopathy
antioxidants
diabetes mellitus
free radicals
high-mobility group box 1 (HMGB1)
inflammatory pathways
novel therapies
diabetic retinopathy (DR)
inflammation
angiogenesis
extracellular vesicles
miRNA
biomarkers
apoptosis
fenofibrate
thioredoxin
hyperglycemia
astaxanthin
carotenoid
reactive oxygen species
photoreceptor cells
PI3K
Nrf2
eicosapentaenoic acid (EPA)
docosahexaenoic acid (DHA)
retinal pigment epithelium
antioxidant
ascorbic acid
retinal disease
vitamin D
GLP-1
superoxide dismutase
biomarkers of diabetic retinopathy
metabolic memory
tear film
aqueous humor
vitreous humor
mitochondria
redox
photoreceptor
glycation
aging
glyoxalase
n/a
thema EDItEUR::M Medicine and Nursing
Oxidative Stress in Diabetic Retinopathy
title Oxidative Stress in Diabetic Retinopathy
title_full Oxidative Stress in Diabetic Retinopathy
title_fullStr Oxidative Stress in Diabetic Retinopathy
title_full_unstemmed Oxidative Stress in Diabetic Retinopathy
title_short Oxidative Stress in Diabetic Retinopathy
title_sort oxidative stress in diabetic retinopathy
topic eicosanoids
oxidative stress
diabetic retinopathy
cyclooxygenase
lipoxygenase
Cytochrome P450
HDAC6
tubastatin A
retinal endothelial cells
retinal endothelial cell senescence
db/db mice
Cinnamomi Ramulus
Paeoniae Radix
CPA4-1
blood-retinal barrier
occludin
human retina
epiretinal membrane
internal limiting membrane
vitreoretinal surgery
macular hole
proliferative diabetic retinopathy
antioxidants
diabetes mellitus
free radicals
high-mobility group box 1 (HMGB1)
inflammatory pathways
novel therapies
diabetic retinopathy (DR)
inflammation
angiogenesis
extracellular vesicles
miRNA
biomarkers
apoptosis
fenofibrate
thioredoxin
hyperglycemia
astaxanthin
carotenoid
reactive oxygen species
photoreceptor cells
PI3K
Nrf2
eicosapentaenoic acid (EPA)
docosahexaenoic acid (DHA)
retinal pigment epithelium
antioxidant
ascorbic acid
retinal disease
vitamin D
GLP-1
superoxide dismutase
biomarkers of diabetic retinopathy
metabolic memory
tear film
aqueous humor
vitreous humor
mitochondria
redox
photoreceptor
glycation
aging
glyoxalase
n/a
thema EDItEUR::M Medicine and Nursing
topic_facet eicosanoids
oxidative stress
diabetic retinopathy
cyclooxygenase
lipoxygenase
Cytochrome P450
HDAC6
tubastatin A
retinal endothelial cells
retinal endothelial cell senescence
db/db mice
Cinnamomi Ramulus
Paeoniae Radix
CPA4-1
blood-retinal barrier
occludin
human retina
epiretinal membrane
internal limiting membrane
vitreoretinal surgery
macular hole
proliferative diabetic retinopathy
antioxidants
diabetes mellitus
free radicals
high-mobility group box 1 (HMGB1)
inflammatory pathways
novel therapies
diabetic retinopathy (DR)
inflammation
angiogenesis
extracellular vesicles
miRNA
biomarkers
apoptosis
fenofibrate
thioredoxin
hyperglycemia
astaxanthin
carotenoid
reactive oxygen species
photoreceptor cells
PI3K
Nrf2
eicosapentaenoic acid (EPA)
docosahexaenoic acid (DHA)
retinal pigment epithelium
antioxidant
ascorbic acid
retinal disease
vitamin D
GLP-1
superoxide dismutase
biomarkers of diabetic retinopathy
metabolic memory
tear film
aqueous humor
vitreous humor
mitochondria
redox
photoreceptor
glycation
aging
glyoxalase
n/a
thema EDItEUR::M Medicine and Nursing
url ONIX_20210501_9783036504483_199