From Basic Research to New Tools and Challenges for the Genotoxicity Testing of Nanomaterials
This Special Issue presents studies on the genotoxicity of nanomaterials. Although nanomaterials provide multiple benefits in a wide range of applications, challenges remain in addressing strong concerns about their risks to the environment and human health. As a result of inconsistencies among publ...
Gorde:
| Formatua: | Online |
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| Hizkuntza: | ingelesa |
| Argitaratua: |
MDPI - Multidisciplinary Digital Publishing Institute
2021
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| Gaiak: | |
| Sarrera elektronikoa: | ONIX_20210501_9783036501123_259 |
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| _version_ | 1869518393999097856 |
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| collection | Directory of Open Access Books |
| description | This Special Issue presents studies on the genotoxicity of nanomaterials. Although nanomaterials provide multiple benefits in a wide range of applications, challenges remain in addressing strong concerns about their risks to the environment and human health. As a result of inconsistencies among published results and diverging conclusions, the understanding of nanomaterial exposure and toxicity remains unclear. Determining whether these materials cause DNA damage—the first step in carcinogenesis—must be a priority in testing. In this book, readers will find recent publications on the genotoxic response to a broad range of nanomaterials, the impact of physico-chemical characteristics, safe-by-design and new developed tools. |
| format | Online |
| id | doab-20.500.12854ir-68513 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-685132024-04-01T23:19:19Z From Basic Research to New Tools and Challenges for the Genotoxicity Testing of Nanomaterials FESSARD, Valérie Nesslany, Fabrice graphene oxide reduced graphene oxide micronucleus oxidative stress safer-by-design tungsten nanoparticles tritiated particles in vitro testing cytotoxicity micronuclei formation DNA damage epigenetics DNA methylation BEAS-2B cells. polystyrene nanoparticles nanoplastics genotoxicity Hs27 human fibroblasts comet assay FPG enzyme TiO2NP SiO2NP ZnONP CeO2NP AgNP multi-walled carbon nanotubes (MWCNT) titanium dioxide nanoparticles lincomycin human amniotic cells in vitro genotoxicity apoptosis nanotoxicology metal oxides high throughput screening micronucleus assay nanomaterial aluminum oral route gut liver V79 cells Hprt advanced in vitro model hepatotoxicity liver spheroids 3D culture HepG2 nongenotoxic silver nanoparticles genotoxic cytotoxic antioxidant activity silver ions Allium cepa metal/coating agent ratio n/a thema EDItEUR::N History and Archaeology::NH History thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBF Social and ethical issues This Special Issue presents studies on the genotoxicity of nanomaterials. Although nanomaterials provide multiple benefits in a wide range of applications, challenges remain in addressing strong concerns about their risks to the environment and human health. As a result of inconsistencies among published results and diverging conclusions, the understanding of nanomaterial exposure and toxicity remains unclear. Determining whether these materials cause DNA damage—the first step in carcinogenesis—must be a priority in testing. In this book, readers will find recent publications on the genotoxic response to a broad range of nanomaterials, the impact of physico-chemical characteristics, safe-by-design and new developed tools. 2021-05-01T15:11:43Z 2021-05-01T15:11:43Z 2021 book ONIX_20210501_9783036501123_259 9783036501123 9783036501130 https://directory.doabooks.org/handle/20.500.12854/68513 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/3533 https://mdpi.com/books/pdfview/book/3533 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-0113-0 10.3390/books978-3-0365-0113-0 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036501123 9783036501130 188 Basel, Switzerland open access |
| spellingShingle | graphene oxide reduced graphene oxide micronucleus oxidative stress safer-by-design tungsten nanoparticles tritiated particles in vitro testing cytotoxicity micronuclei formation DNA damage epigenetics DNA methylation BEAS-2B cells. polystyrene nanoparticles nanoplastics genotoxicity Hs27 human fibroblasts comet assay FPG enzyme TiO2NP SiO2NP ZnONP CeO2NP AgNP multi-walled carbon nanotubes (MWCNT) titanium dioxide nanoparticles lincomycin human amniotic cells in vitro genotoxicity apoptosis nanotoxicology metal oxides high throughput screening micronucleus assay nanomaterial aluminum oral route gut liver V79 cells Hprt advanced in vitro model hepatotoxicity liver spheroids 3D culture HepG2 nongenotoxic silver nanoparticles genotoxic cytotoxic antioxidant activity silver ions Allium cepa metal/coating agent ratio n/a thema EDItEUR::N History and Archaeology::NH History thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBF Social and ethical issues From Basic Research to New Tools and Challenges for the Genotoxicity Testing of Nanomaterials |
| title | From Basic Research to New Tools and Challenges for the Genotoxicity Testing of Nanomaterials |
| title_full | From Basic Research to New Tools and Challenges for the Genotoxicity Testing of Nanomaterials |
| title_fullStr | From Basic Research to New Tools and Challenges for the Genotoxicity Testing of Nanomaterials |
| title_full_unstemmed | From Basic Research to New Tools and Challenges for the Genotoxicity Testing of Nanomaterials |
| title_short | From Basic Research to New Tools and Challenges for the Genotoxicity Testing of Nanomaterials |
| title_sort | from basic research to new tools and challenges for the genotoxicity testing of nanomaterials |
| topic | graphene oxide reduced graphene oxide micronucleus oxidative stress safer-by-design tungsten nanoparticles tritiated particles in vitro testing cytotoxicity micronuclei formation DNA damage epigenetics DNA methylation BEAS-2B cells. polystyrene nanoparticles nanoplastics genotoxicity Hs27 human fibroblasts comet assay FPG enzyme TiO2NP SiO2NP ZnONP CeO2NP AgNP multi-walled carbon nanotubes (MWCNT) titanium dioxide nanoparticles lincomycin human amniotic cells in vitro genotoxicity apoptosis nanotoxicology metal oxides high throughput screening micronucleus assay nanomaterial aluminum oral route gut liver V79 cells Hprt advanced in vitro model hepatotoxicity liver spheroids 3D culture HepG2 nongenotoxic silver nanoparticles genotoxic cytotoxic antioxidant activity silver ions Allium cepa metal/coating agent ratio n/a thema EDItEUR::N History and Archaeology::NH History thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBF Social and ethical issues |
| topic_facet | graphene oxide reduced graphene oxide micronucleus oxidative stress safer-by-design tungsten nanoparticles tritiated particles in vitro testing cytotoxicity micronuclei formation DNA damage epigenetics DNA methylation BEAS-2B cells. polystyrene nanoparticles nanoplastics genotoxicity Hs27 human fibroblasts comet assay FPG enzyme TiO2NP SiO2NP ZnONP CeO2NP AgNP multi-walled carbon nanotubes (MWCNT) titanium dioxide nanoparticles lincomycin human amniotic cells in vitro genotoxicity apoptosis nanotoxicology metal oxides high throughput screening micronucleus assay nanomaterial aluminum oral route gut liver V79 cells Hprt advanced in vitro model hepatotoxicity liver spheroids 3D culture HepG2 nongenotoxic silver nanoparticles genotoxic cytotoxic antioxidant activity silver ions Allium cepa metal/coating agent ratio n/a thema EDItEUR::N History and Archaeology::NH History thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBF Social and ethical issues |
| url | ONIX_20210501_9783036501123_259 |