Pharmaceutical Particulates and Membranes for Delivery of Drugs and Bioactive Molecules

This book is a collection of papers published in the Special Issue of Pharmaceutics, entitled "Pharmaceutical Particulates and Membranes for Delivery of Drugs and Bioactive Molecules". A drug release profile is a consequential factor for nanoparticle application, directly related to drug stability a...

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collection Directory of Open Access Books
description This book is a collection of papers published in the Special Issue of Pharmaceutics, entitled "Pharmaceutical Particulates and Membranes for Delivery of Drugs and Bioactive Molecules". A drug release profile is a consequential factor for nanoparticle application, directly related to drug stability and therapeutic results, as well as formulation development. Pharmaceutical particulates of different sizes and shapes (e.g., liposomes, oil-in-water emulsions, polymeric nano- and microspheres, metallic nanoparticles (NPs) such as gold, silver and iron oxide crystals, and core-shell hybrid NPs) offer many diagnostic and therapeutic applications. Membranes are also extensively utilized in many applications. They are especially beneficial to the distribution of macromolecular drugs and biopharmaceutical drugs (peptides, proteins, antibodies, oligonucleotides, plasmids, and viruses) with physicochemical and pharmacokinetic vulnerability. The delivery of drugs and bioactive molecules using particulates and membranes has gained a great deal of attention for various applications, such as the treatment of secondary infections, cancer treatment, skin regeneration, orthopaedic applications, and antimicrobial drug delivery. In addition, several production techniques have been utilized for the fabrication of particulates and membranes in the last decade, which include lyophilisation, micro-emulsion, nano-spray dryer, nano-electrospinning, slip casting and 3D printers. Therefore, pharmaceutical particulates and membranes possess excellent prospects to deliver drugs and bioactive molecules with the potential to improve new delivery strategies like sustained and controlled release.
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language eng
publishDate 2021
publishDateRange 2021
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publisher MDPI - Multidisciplinary Digital Publishing Institute
publisherStr MDPI - Multidisciplinary Digital Publishing Institute
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spelling doab-20.500.12854ir-686572024-03-28T03:33:34Z Pharmaceutical Particulates and Membranes for Delivery of Drugs and Bioactive Molecules Das, Diganta B. Arthanareeswaran, G Mabrouk, Mostafa Beherei, Hanan H. alginate gelispheres textural analysis crosslinked matrices PLGA discs prolonged release powder flow properties microfluidics coculture HER2 polystyrene µPs biofunctionalization coaxial electrospraying polymeric nanoparticles spreading angle process-property-performance relationship nanoemulsion mixture design aqueous humor antimicrobial activity sustained release pellets double coating layer loxoprofen citric acid pharmacokinetic studies biomimetic magnetite drug delivery magnetic hyperthermia magnetite MamC nanoparticles stability pharmaceutical particulates membranes drug delivery systems bio-imaging bioactive molecules composite N-hydroxyphthalimide carbon dots polymer gels antitumoral activity wound dressing polymeric membrane nanoparticles curcumin alginate pluronic F68 drug skin permeation Franz cells tape stripping wound infection biofilm pseudomonas aeruginosa antimicrobial delivery polyvinylpyrrolidone nanofibers red blood cells membrane arsenic trioxide sodium alginate nanoparticles reduce toxicity anti-tumor pediatric drug delivery tuberculosis reconstitutable dry suspension isoniazid polymer-lipid microparticulate direct emulsification n/a thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences This book is a collection of papers published in the Special Issue of Pharmaceutics, entitled "Pharmaceutical Particulates and Membranes for Delivery of Drugs and Bioactive Molecules". A drug release profile is a consequential factor for nanoparticle application, directly related to drug stability and therapeutic results, as well as formulation development. Pharmaceutical particulates of different sizes and shapes (e.g., liposomes, oil-in-water emulsions, polymeric nano- and microspheres, metallic nanoparticles (NPs) such as gold, silver and iron oxide crystals, and core-shell hybrid NPs) offer many diagnostic and therapeutic applications. Membranes are also extensively utilized in many applications. They are especially beneficial to the distribution of macromolecular drugs and biopharmaceutical drugs (peptides, proteins, antibodies, oligonucleotides, plasmids, and viruses) with physicochemical and pharmacokinetic vulnerability. The delivery of drugs and bioactive molecules using particulates and membranes has gained a great deal of attention for various applications, such as the treatment of secondary infections, cancer treatment, skin regeneration, orthopaedic applications, and antimicrobial drug delivery. In addition, several production techniques have been utilized for the fabrication of particulates and membranes in the last decade, which include lyophilisation, micro-emulsion, nano-spray dryer, nano-electrospinning, slip casting and 3D printers. Therefore, pharmaceutical particulates and membranes possess excellent prospects to deliver drugs and bioactive molecules with the potential to improve new delivery strategies like sustained and controlled release. 2021-05-01T15:26:11Z 2021-05-01T15:26:11Z 2020 book ONIX_20210501_9783039363926_403 9783039363926 9783039363933 https://directory.doabooks.org/handle/20.500.12854/68657 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/2420 https://mdpi.com/books/pdfview/book/2420 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-03936-393-3 10.3390/books978-3-03936-393-3 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783039363926 9783039363933 220 Basel, Switzerland open access
spellingShingle alginate gelispheres
textural analysis
crosslinked matrices
PLGA discs
prolonged release
powder flow properties
microfluidics
coculture
HER2
polystyrene µPs
biofunctionalization
coaxial electrospraying
polymeric nanoparticles
spreading angle
process-property-performance relationship
nanoemulsion
mixture design
aqueous humor
antimicrobial activity
sustained release pellets
double coating layer
loxoprofen
citric acid
pharmacokinetic studies
biomimetic magnetite
drug delivery
magnetic hyperthermia
magnetite
MamC
nanoparticles stability
pharmaceutical particulates
membranes
drug delivery systems
bio-imaging
bioactive molecules
composite
N-hydroxyphthalimide
carbon dots
polymer gels
antitumoral activity
wound dressing
polymeric membrane
nanoparticles
curcumin
alginate
pluronic F68
drug skin permeation
Franz cells
tape stripping
wound infection
biofilm
pseudomonas aeruginosa
antimicrobial delivery
polyvinylpyrrolidone
nanofibers
red blood cells membrane
arsenic trioxide
sodium alginate nanoparticles
reduce toxicity
anti-tumor
pediatric drug delivery
tuberculosis
reconstitutable dry suspension
isoniazid
polymer-lipid
microparticulate
direct emulsification
n/a
thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
Pharmaceutical Particulates and Membranes for Delivery of Drugs and Bioactive Molecules
title Pharmaceutical Particulates and Membranes for Delivery of Drugs and Bioactive Molecules
title_full Pharmaceutical Particulates and Membranes for Delivery of Drugs and Bioactive Molecules
title_fullStr Pharmaceutical Particulates and Membranes for Delivery of Drugs and Bioactive Molecules
title_full_unstemmed Pharmaceutical Particulates and Membranes for Delivery of Drugs and Bioactive Molecules
title_short Pharmaceutical Particulates and Membranes for Delivery of Drugs and Bioactive Molecules
title_sort pharmaceutical particulates and membranes for delivery of drugs and bioactive molecules
topic alginate gelispheres
textural analysis
crosslinked matrices
PLGA discs
prolonged release
powder flow properties
microfluidics
coculture
HER2
polystyrene µPs
biofunctionalization
coaxial electrospraying
polymeric nanoparticles
spreading angle
process-property-performance relationship
nanoemulsion
mixture design
aqueous humor
antimicrobial activity
sustained release pellets
double coating layer
loxoprofen
citric acid
pharmacokinetic studies
biomimetic magnetite
drug delivery
magnetic hyperthermia
magnetite
MamC
nanoparticles stability
pharmaceutical particulates
membranes
drug delivery systems
bio-imaging
bioactive molecules
composite
N-hydroxyphthalimide
carbon dots
polymer gels
antitumoral activity
wound dressing
polymeric membrane
nanoparticles
curcumin
alginate
pluronic F68
drug skin permeation
Franz cells
tape stripping
wound infection
biofilm
pseudomonas aeruginosa
antimicrobial delivery
polyvinylpyrrolidone
nanofibers
red blood cells membrane
arsenic trioxide
sodium alginate nanoparticles
reduce toxicity
anti-tumor
pediatric drug delivery
tuberculosis
reconstitutable dry suspension
isoniazid
polymer-lipid
microparticulate
direct emulsification
n/a
thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
topic_facet alginate gelispheres
textural analysis
crosslinked matrices
PLGA discs
prolonged release
powder flow properties
microfluidics
coculture
HER2
polystyrene µPs
biofunctionalization
coaxial electrospraying
polymeric nanoparticles
spreading angle
process-property-performance relationship
nanoemulsion
mixture design
aqueous humor
antimicrobial activity
sustained release pellets
double coating layer
loxoprofen
citric acid
pharmacokinetic studies
biomimetic magnetite
drug delivery
magnetic hyperthermia
magnetite
MamC
nanoparticles stability
pharmaceutical particulates
membranes
drug delivery systems
bio-imaging
bioactive molecules
composite
N-hydroxyphthalimide
carbon dots
polymer gels
antitumoral activity
wound dressing
polymeric membrane
nanoparticles
curcumin
alginate
pluronic F68
drug skin permeation
Franz cells
tape stripping
wound infection
biofilm
pseudomonas aeruginosa
antimicrobial delivery
polyvinylpyrrolidone
nanofibers
red blood cells membrane
arsenic trioxide
sodium alginate nanoparticles
reduce toxicity
anti-tumor
pediatric drug delivery
tuberculosis
reconstitutable dry suspension
isoniazid
polymer-lipid
microparticulate
direct emulsification
n/a
thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
url ONIX_20210501_9783039363926_403