New Horizons in Time-Domain Diffuse Optical Spectroscopy and Imaging

Jöbsis was the first to describe the in vivo application of near-infrared spectroscopy (NIRS), also called diffuse optical spectroscopy (DOS). NIRS was originally designed for the clinical monitoring of tissue oxygenation, and today it has also become a useful tool for neuroimaging studies (function...

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collection Directory of Open Access Books
description Jöbsis was the first to describe the in vivo application of near-infrared spectroscopy (NIRS), also called diffuse optical spectroscopy (DOS). NIRS was originally designed for the clinical monitoring of tissue oxygenation, and today it has also become a useful tool for neuroimaging studies (functional near-infrared spectroscopy, fNIRS). However, difficulties in the selective and quantitative measurements of tissue hemoglobin (Hb), which have been central in the NIRS field for over 40 years, remain to be solved. To overcome these problems, time-domain (TD) and frequency-domain (FD) measurements have been tried. Presently, a wide range of NIRS instruments are available, including commonly available commercial instruments for continuous wave (CW) measurements, based on the modified Beer–Lambert law (steady-state domain measurements). Among these measurements, the TD measurement is the most promising approach, although compared with CW and FD measurements, TD measurements are less common, due to the need for large and expensive instruments with poor temporal resolution and limited dynamic range. However, thanks to technological developments, TD measurements are increasingly being used in research, and also in various clinical settings. This Special Issue highlights issues at the cutting edge of TD DOS and diffuse optical tomography (DOT). It covers all aspects related to TD measurements, including advances in hardware, methodology, the theory of light propagation, and clinical applications.
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spelling doab-20.500.12854ir-686632024-03-31T13:08:30Z New Horizons in Time-Domain Diffuse Optical Spectroscopy and Imaging Hoshi, Yoko breast cancer diffuse optical spectroscopy chemotherapy time-domain spectroscopy near-infrared spectroscopy radiative transfer equation diffusion equation biological tissue time-domain instruments light propagation in tissue optical properties of tissue diffuse optical tomography fluorescence diffuse optical tomography time-resolved spectroscopy NIRS diffuse optics time-domain time-resolved brain oxygenation tissue saturation scattering absorption 3-hour sitting near infrared time-resolved spectroscopy compression stocking tissue oxygenation extracellular water intracellular water circumference gastrocnemius neonate vaginal delivery cerebral blood volume cerebral hemoglobin oxygen saturation near-infrared time-resolved spectroscopy near infrared spectroscopy aging prefrontal cortex TRS magnetic resonance imaging brain atrophy VSRAD optical pathlength hemoglobin cognitive function time-domain NIRS null source-detector separation brain noninvasive subcutaneous white adipose tissue tissue total hemoglobin diffuse light inverse problems optical tomography inverse problem datatypes diffusion approximation highly forward scattering of photons diffusion and delta-Eddington approximations characteristic length and time scales of photon transport n/a thema EDItEUR::M Medicine and Nursing thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences Jöbsis was the first to describe the in vivo application of near-infrared spectroscopy (NIRS), also called diffuse optical spectroscopy (DOS). NIRS was originally designed for the clinical monitoring of tissue oxygenation, and today it has also become a useful tool for neuroimaging studies (functional near-infrared spectroscopy, fNIRS). However, difficulties in the selective and quantitative measurements of tissue hemoglobin (Hb), which have been central in the NIRS field for over 40 years, remain to be solved. To overcome these problems, time-domain (TD) and frequency-domain (FD) measurements have been tried. Presently, a wide range of NIRS instruments are available, including commonly available commercial instruments for continuous wave (CW) measurements, based on the modified Beer–Lambert law (steady-state domain measurements). Among these measurements, the TD measurement is the most promising approach, although compared with CW and FD measurements, TD measurements are less common, due to the need for large and expensive instruments with poor temporal resolution and limited dynamic range. However, thanks to technological developments, TD measurements are increasingly being used in research, and also in various clinical settings. This Special Issue highlights issues at the cutting edge of TD DOS and diffuse optical tomography (DOT). It covers all aspects related to TD measurements, including advances in hardware, methodology, the theory of light propagation, and clinical applications. 2021-05-01T15:26:20Z 2021-05-01T15:26:20Z 2020 book ONIX_20210501_9783039361007_409 9783039361007 9783039361014 https://directory.doabooks.org/handle/20.500.12854/68663 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/2426 https://mdpi.com/books/pdfview/book/2426 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-03936-101-4 10.3390/books978-3-03936-101-4 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783039361007 9783039361014 246 Basel, Switzerland open access
spellingShingle breast cancer
diffuse optical spectroscopy
chemotherapy
time-domain spectroscopy
near-infrared spectroscopy
radiative transfer equation
diffusion equation
biological tissue
time-domain instruments
light propagation in tissue
optical properties of tissue
diffuse optical tomography
fluorescence diffuse optical tomography
time-resolved spectroscopy
NIRS
diffuse optics
time-domain
time-resolved
brain oxygenation
tissue saturation
scattering
absorption
3-hour sitting
near infrared time-resolved spectroscopy
compression stocking
tissue oxygenation
extracellular water
intracellular water
circumference
gastrocnemius
neonate
vaginal delivery
cerebral blood volume
cerebral hemoglobin oxygen saturation
near-infrared time-resolved spectroscopy
near infrared spectroscopy
aging
prefrontal cortex
TRS
magnetic resonance imaging
brain atrophy
VSRAD
optical pathlength
hemoglobin
cognitive function
time-domain NIRS
null source-detector separation
brain
noninvasive
subcutaneous white adipose tissue
tissue total hemoglobin
diffuse light
inverse problems
optical tomography
inverse problem
datatypes
diffusion approximation
highly forward scattering of photons
diffusion and delta-Eddington approximations
characteristic length and time scales of photon transport
n/a
thema EDItEUR::M Medicine and Nursing
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
New Horizons in Time-Domain Diffuse Optical Spectroscopy and Imaging
title New Horizons in Time-Domain Diffuse Optical Spectroscopy and Imaging
title_full New Horizons in Time-Domain Diffuse Optical Spectroscopy and Imaging
title_fullStr New Horizons in Time-Domain Diffuse Optical Spectroscopy and Imaging
title_full_unstemmed New Horizons in Time-Domain Diffuse Optical Spectroscopy and Imaging
title_short New Horizons in Time-Domain Diffuse Optical Spectroscopy and Imaging
title_sort new horizons in time domain diffuse optical spectroscopy and imaging
topic breast cancer
diffuse optical spectroscopy
chemotherapy
time-domain spectroscopy
near-infrared spectroscopy
radiative transfer equation
diffusion equation
biological tissue
time-domain instruments
light propagation in tissue
optical properties of tissue
diffuse optical tomography
fluorescence diffuse optical tomography
time-resolved spectroscopy
NIRS
diffuse optics
time-domain
time-resolved
brain oxygenation
tissue saturation
scattering
absorption
3-hour sitting
near infrared time-resolved spectroscopy
compression stocking
tissue oxygenation
extracellular water
intracellular water
circumference
gastrocnemius
neonate
vaginal delivery
cerebral blood volume
cerebral hemoglobin oxygen saturation
near-infrared time-resolved spectroscopy
near infrared spectroscopy
aging
prefrontal cortex
TRS
magnetic resonance imaging
brain atrophy
VSRAD
optical pathlength
hemoglobin
cognitive function
time-domain NIRS
null source-detector separation
brain
noninvasive
subcutaneous white adipose tissue
tissue total hemoglobin
diffuse light
inverse problems
optical tomography
inverse problem
datatypes
diffusion approximation
highly forward scattering of photons
diffusion and delta-Eddington approximations
characteristic length and time scales of photon transport
n/a
thema EDItEUR::M Medicine and Nursing
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
topic_facet breast cancer
diffuse optical spectroscopy
chemotherapy
time-domain spectroscopy
near-infrared spectroscopy
radiative transfer equation
diffusion equation
biological tissue
time-domain instruments
light propagation in tissue
optical properties of tissue
diffuse optical tomography
fluorescence diffuse optical tomography
time-resolved spectroscopy
NIRS
diffuse optics
time-domain
time-resolved
brain oxygenation
tissue saturation
scattering
absorption
3-hour sitting
near infrared time-resolved spectroscopy
compression stocking
tissue oxygenation
extracellular water
intracellular water
circumference
gastrocnemius
neonate
vaginal delivery
cerebral blood volume
cerebral hemoglobin oxygen saturation
near-infrared time-resolved spectroscopy
near infrared spectroscopy
aging
prefrontal cortex
TRS
magnetic resonance imaging
brain atrophy
VSRAD
optical pathlength
hemoglobin
cognitive function
time-domain NIRS
null source-detector separation
brain
noninvasive
subcutaneous white adipose tissue
tissue total hemoglobin
diffuse light
inverse problems
optical tomography
inverse problem
datatypes
diffusion approximation
highly forward scattering of photons
diffusion and delta-Eddington approximations
characteristic length and time scales of photon transport
n/a
thema EDItEUR::M Medicine and Nursing
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
url ONIX_20210501_9783039361007_409