Frontiers in the Actin Cytoskeleton

This Special Issue of IJMS covers a broad range of cutting-edge aspects related to the organization, function, and role in disease of the actin cytoskeleton. This cellular structure is of fundamental importance for the homeostasis of every eukaryotic cell, from the simplest unicellular organism to t...

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Wydane: MDPI - Multidisciplinary Digital Publishing Institute 2021
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description This Special Issue of IJMS covers a broad range of cutting-edge aspects related to the organization, function, and role in disease of the actin cytoskeleton. This cellular structure is of fundamental importance for the homeostasis of every eukaryotic cell, from the simplest unicellular organism to the most complex animal cell. The actin cytoskeleton contributes to developing and maintaining cell shape and tissue integrity and is crucial for cell migration, movement of organelles, vesicle trafficking, and the completion of cell division. Elaborate structures like the sarcomere, the inner ear cell stereocilia, and the brush border microvilli are built on actin filament scaffolds. Dozens of actin-binding proteins orchestrate the dynamic remodeling of the actin cytoskeleton and integrate it with microtubules and intermediate filaments and with the cell signaling machinery. Playing such fundamental roles in a plethora of cellular processes, it comes as no surprise that defects in actin and associated proteins have been found to be implicated in pathological conditions as diverse as myopathies and neurodegenerative diseases. This Special Issue gathers 15 contributions highlighting the impressive advances made in recent years in this exciting field.
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publishDate 2021
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publisherStr MDPI - Multidisciplinary Digital Publishing Institute
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spelling doab-20.500.12854ir-687802024-03-28T03:33:41Z Frontiers in the Actin Cytoskeleton Rivero, Francisco thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences This Special Issue of IJMS covers a broad range of cutting-edge aspects related to the organization, function, and role in disease of the actin cytoskeleton. This cellular structure is of fundamental importance for the homeostasis of every eukaryotic cell, from the simplest unicellular organism to the most complex animal cell. The actin cytoskeleton contributes to developing and maintaining cell shape and tissue integrity and is crucial for cell migration, movement of organelles, vesicle trafficking, and the completion of cell division. Elaborate structures like the sarcomere, the inner ear cell stereocilia, and the brush border microvilli are built on actin filament scaffolds. Dozens of actin-binding proteins orchestrate the dynamic remodeling of the actin cytoskeleton and integrate it with microtubules and intermediate filaments and with the cell signaling machinery. Playing such fundamental roles in a plethora of cellular processes, it comes as no surprise that defects in actin and associated proteins have been found to be implicated in pathological conditions as diverse as myopathies and neurodegenerative diseases. This Special Issue gathers 15 contributions highlighting the impressive advances made in recent years in this exciting field. 2021-05-01T15:29:13Z 2021-05-01T15:29:13Z 2020 book ONIX_20210501_9783039365654_526 9783039365654 9783039365661 https://directory.doabooks.org/handle/20.500.12854/68780 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/2546 https://mdpi.com/books/pdfview/book/2546 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-03936-566-1 10.3390/books978-3-03936-566-1 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783039365654 9783039365661 274 Basel, Switzerland open access
spellingShingle thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
Frontiers in the Actin Cytoskeleton
title Frontiers in the Actin Cytoskeleton
title_full Frontiers in the Actin Cytoskeleton
title_fullStr Frontiers in the Actin Cytoskeleton
title_full_unstemmed Frontiers in the Actin Cytoskeleton
title_short Frontiers in the Actin Cytoskeleton
title_sort frontiers in the actin cytoskeleton
topic thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
topic_facet thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
url ONIX_20210501_9783039365654_526