The Role of Selenium in Health and Disease

“Role of selenium in health and disease”. This book contains ten articles covering recent advances in our understanding of the relationship between the essential micronutrient selenium and human healt...

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Формат: Online
Язык:английский
Опубликовано: MDPI - Multidisciplinary Digital Publishing Institute 2021
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Online-ссылка:ONIX_20210501_9783039361465_532
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collection Directory of Open Access Books
description “Role of selenium in health and disease”. This book contains ten articles covering recent advances in our understanding of the relationship between the essential micronutrient selenium and human health and disease. Taken together, these articles strengthen the evidence showing that selenium, as a constituent of selenoproteins, is central to biological stress responses and mechanisms commonly altered in most complex disorders. Relevant to public health concerns, this book also emphasizes the U-shaped dose-response relationship between selenium concentration and disease risk across diverse populations from Europe [articles 2,3,6], the Middle East and North Africa [9], and Taiwan [5]. This highlights the importance of personalized nutrition strategies targeted at individuals with increased risk of disease and low selenium intake. The mechanisms by which selenium status, selenoprotein expression, and inherited genetic variations in the selenium pathway interact to affect molecular pathways involved in disease development are explored in human cohorts [2,3,5-7], and in animal [4] and in vitro models [8]. Furthermore, some reports identified novel potential biomarkers of disease risk and prognosis within the selenium pathway that could further our understanding of many chronic diseases [2,3]. Overall, this book broadens our understanding of the role of selenium in chronic diseases, and provides new directions for future preventative approaches.
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language eng
publishDate 2021
publishDateRange 2021
publishDateSort 2021
publisher MDPI - Multidisciplinary Digital Publishing Institute
publisherStr MDPI - Multidisciplinary Digital Publishing Institute
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spelling doab-20.500.12854ir-687862024-03-28T03:30:45Z The Role of Selenium in Health and Disease Méplan, Catherine Hughes, David J. thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBC Cultural and media studies::JBCC Cultural studies::JBCC4 Cultural studies: food and society “Role of selenium in health and disease”. This book contains ten articles covering recent advances in our understanding of the relationship between the essential micronutrient selenium and human health and disease. Taken together, these articles strengthen the evidence showing that selenium, as a constituent of selenoproteins, is central to biological stress responses and mechanisms commonly altered in most complex disorders. Relevant to public health concerns, this book also emphasizes the U-shaped dose-response relationship between selenium concentration and disease risk across diverse populations from Europe [articles 2,3,6], the Middle East and North Africa [9], and Taiwan [5]. This highlights the importance of personalized nutrition strategies targeted at individuals with increased risk of disease and low selenium intake. The mechanisms by which selenium status, selenoprotein expression, and inherited genetic variations in the selenium pathway interact to affect molecular pathways involved in disease development are explored in human cohorts [2,3,5-7], and in animal [4] and in vitro models [8]. Furthermore, some reports identified novel potential biomarkers of disease risk and prognosis within the selenium pathway that could further our understanding of many chronic diseases [2,3]. Overall, this book broadens our understanding of the role of selenium in chronic diseases, and provides new directions for future preventative approaches. 2021-05-01T15:29:21Z 2021-05-01T15:29:21Z 2020 book ONIX_20210501_9783039361465_532 9783039361465 9783039361472 https://directory.doabooks.org/handle/20.500.12854/68786 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/2552 https://mdpi.com/books/pdfview/book/2552 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-03936-147-2 10.3390/books978-3-03936-147-2 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783039361465 9783039361472 170 Basel, Switzerland open access
spellingShingle thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBC Cultural and media studies::JBCC Cultural studies::JBCC4 Cultural studies: food and society
The Role of Selenium in Health and Disease
title The Role of Selenium in Health and Disease
title_full The Role of Selenium in Health and Disease
title_fullStr The Role of Selenium in Health and Disease
title_full_unstemmed The Role of Selenium in Health and Disease
title_short The Role of Selenium in Health and Disease
title_sort role of selenium in health and disease
topic thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBC Cultural and media studies::JBCC Cultural studies::JBCC4 Cultural studies: food and society
topic_facet thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBC Cultural and media studies::JBCC Cultural studies::JBCC4 Cultural studies: food and society
url ONIX_20210501_9783039361465_532