Glioblastoma: State of the Art and Future Perspectives
Glioblastoma is an aggressive incurable primary tumor of the central nervous system. Median overall survival is in the range of 1.5 years even in selected clinical trials populations. Many features contribute to this therapeutic challenge including high intratumoral and intertumoral heterogeneity, r...
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| 格式: | Online |
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| 語言: | 英语 |
| 出版: |
MDPI - Multidisciplinary Digital Publishing Institute
2021
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| 主題: | |
| 在線閱讀: | ONIX_20210501_9783039282609_557 |
| 標簽: |
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| _version_ | 1869520268272074752 |
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| collection | Directory of Open Access Books |
| description | Glioblastoma is an aggressive incurable primary tumor of the central nervous system. Median overall survival is in the range of 1.5 years even in selected clinical trials populations. Many features contribute to this therapeutic challenge including high intratumoral and intertumoral heterogeneity, resistance to therapy, migration and invasion, immunosuppression. With the access of novel highthroughput technologies, significant progress has been made to understand molecular and immunological signatures underlying the pathology of glioblastoma. Clinical trial designs have shifted from investigating broad “one-for-all” treatment approaches to precision oncology designs. The collection of contributions in this book aim at providing researchers and clinicians an update on different aspects of glioblastoma, i.e. progress in basic, preclinical and clinical research. |
| format | Online |
| id | doab-20.500.12854ir-68811 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-688112024-03-28T03:33:30Z Glioblastoma: State of the Art and Future Perspectives Tabatabai, Ghazaleh Wakimoto, Hiroaki thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences Glioblastoma is an aggressive incurable primary tumor of the central nervous system. Median overall survival is in the range of 1.5 years even in selected clinical trials populations. Many features contribute to this therapeutic challenge including high intratumoral and intertumoral heterogeneity, resistance to therapy, migration and invasion, immunosuppression. With the access of novel highthroughput technologies, significant progress has been made to understand molecular and immunological signatures underlying the pathology of glioblastoma. Clinical trial designs have shifted from investigating broad “one-for-all” treatment approaches to precision oncology designs. The collection of contributions in this book aim at providing researchers and clinicians an update on different aspects of glioblastoma, i.e. progress in basic, preclinical and clinical research. 2021-05-01T15:29:51Z 2021-05-01T15:29:51Z 2020 book ONIX_20210501_9783039282609_557 9783039282609 9783039282616 https://directory.doabooks.org/handle/20.500.12854/68811 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/2577 https://mdpi.com/books/pdfview/book/2577 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-03928-261-6 10.3390/books978-3-03928-261-6 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783039282609 9783039282616 784 Basel, Switzerland open access |
| spellingShingle | thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences Glioblastoma: State of the Art and Future Perspectives |
| title | Glioblastoma: State of the Art and Future Perspectives |
| title_full | Glioblastoma: State of the Art and Future Perspectives |
| title_fullStr | Glioblastoma: State of the Art and Future Perspectives |
| title_full_unstemmed | Glioblastoma: State of the Art and Future Perspectives |
| title_short | Glioblastoma: State of the Art and Future Perspectives |
| title_sort | glioblastoma state of the art and future perspectives |
| topic | thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences |
| topic_facet | thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences |
| url | ONIX_20210501_9783039282609_557 |