Design and Synthesis of Organic Molecules as Antineoplastic Agents

This book is a collection of Special Issue articles with a multidisciplinary character, linking biology, medicine, and synthetic organic chemistry. The synthesis and full characterization of about 180 novel organic species, both of natural and synthetic origin, often designed with the support of in-...

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Argitaratua: MDPI - Multidisciplinary Digital Publishing Institute 2021
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Sarrera elektronikoa:ONIX_20210501_9783039366668_616
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collection Directory of Open Access Books
description This book is a collection of Special Issue articles with a multidisciplinary character, linking biology, medicine, and synthetic organic chemistry. The synthesis and full characterization of about 180 novel organic species, both of natural and synthetic origin, often designed with the support of in-silico studies, are set out in the book. In several articles, molecular hybridization approaches have been used as a successful multi-target strategy for the design and development of novel antitumor agents. Rigorous and careful biochemical studies ranging from in-vitro experiments on a plethora of human-cancer derived cell lines to in-vivo and ex-vivo studies allowed the authors to identify the molecular targets and gain useful information on structure–activity relationships (SAR). For this reason, this collection should interest many readers from different scientific fields.
format Online
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institution Directory of Open Access Books
language eng
publishDate 2021
publishDateRange 2021
publishDateSort 2021
publisher MDPI - Multidisciplinary Digital Publishing Institute
publisherStr MDPI - Multidisciplinary Digital Publishing Institute
record_format ojs
spelling doab-20.500.12854ir-688702024-03-27T16:34:23Z Design and Synthesis of Organic Molecules as Antineoplastic Agents Boga, Carla Micheletti, Gabriele thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general This book is a collection of Special Issue articles with a multidisciplinary character, linking biology, medicine, and synthetic organic chemistry. The synthesis and full characterization of about 180 novel organic species, both of natural and synthetic origin, often designed with the support of in-silico studies, are set out in the book. In several articles, molecular hybridization approaches have been used as a successful multi-target strategy for the design and development of novel antitumor agents. Rigorous and careful biochemical studies ranging from in-vitro experiments on a plethora of human-cancer derived cell lines to in-vivo and ex-vivo studies allowed the authors to identify the molecular targets and gain useful information on structure–activity relationships (SAR). For this reason, this collection should interest many readers from different scientific fields. 2021-05-01T15:31:44Z 2021-05-01T15:31:44Z 2020 book ONIX_20210501_9783039366668_616 9783039366668 9783039366675 https://directory.doabooks.org/handle/20.500.12854/68870 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/2637 https://mdpi.com/books/pdfview/book/2637 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-03936-667-5 10.3390/books978-3-03936-667-5 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783039366668 9783039366675 210 Basel, Switzerland open access
spellingShingle thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
Design and Synthesis of Organic Molecules as Antineoplastic Agents
title Design and Synthesis of Organic Molecules as Antineoplastic Agents
title_full Design and Synthesis of Organic Molecules as Antineoplastic Agents
title_fullStr Design and Synthesis of Organic Molecules as Antineoplastic Agents
title_full_unstemmed Design and Synthesis of Organic Molecules as Antineoplastic Agents
title_short Design and Synthesis of Organic Molecules as Antineoplastic Agents
title_sort design and synthesis of organic molecules as antineoplastic agents
topic thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
topic_facet thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
url ONIX_20210501_9783039366668_616