Five Years of Separations

Five years of Separations are celebrated by a collection of ten feature articles: one review and nine research articles on topics of current interest. Applications of Gas Chromatography for the Analysis of Tricyclic Antidepressants in Biological Matrices are presented focusing on novel extraction te...

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Publié: MDPI - Multidisciplinary Digital Publishing Institute 2021
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description Five years of Separations are celebrated by a collection of ten feature articles: one review and nine research articles on topics of current interest. Applications of Gas Chromatography for the Analysis of Tricyclic Antidepressants in Biological Matrices are presented focusing on novel extraction techniques and novel materials used for sample preparation due to the great demand for method development for the determination of TCAs in biofluids, especially for therapeutic drug monitoring. Original research articles include the following: 1. Insights into the Mechanism of Separation of Bisphosphonates by Zwitterionic Hydrophilic Interaction Liquid Chromatography: Application to the Quantitation of Risedronate in Pharmaceuticals. 2. A method based on micro-matrix solid-phase dispersion (μ-MSPD) followed by gas-chromatography tandem mass spectrometry (GC–MS/MS), developed to analyze UV filters in personal care products. 3. The performance of a vibratory shear-enhanced process (VSEP) combined with an appropriate membrane unit for the treatment of simulated or industrial tannery wastewaters. 4. A method for the analysis of thyroid hormones by liquid chromatography-mass spectrometry that was used for the dissolution testing of single- and dual-component thyroid hormone supplements via a two-stage biorelevant dissolution procedure. 5. A method involving the collection and determination of organic and inorganic gunshot residues on hands using online in-tube solid-phase microextraction (IT-SPME) coupled to miniaturized capillary liquid chromatography with diode array detection (CapLC-DAD) and scanning electron microscopy coupled to energy dispersion X-ray (SEM-EDX), respectively, for quantifying both residues. 6. The gas chromatographic retention behavior of 16 polycyclic aromatic hydrocarbons (PAHs) and alkylated PAHs on a new ionic liquid stationary phase, 1,12-di(tripropylphosphonium) dodecane bis(trifluoromethanesulfonyl)imide (SLB®-ILPAH) intended for the separation of PAH mixtures, which was compared with the elution pattern on more traditional stationary phases: a non-polar phenyl arylene (DB-5ms) and a semipolar 50% phenyl dimethyl siloxane (SLB PAHms) column. 7. The Multiple-Stage Precursor Ion Separation and High Resolution Mass Spectrometry toward Structural Characterization of 2,3-Diacyltrehalose Family from Mycobacterium tuberculosis 8. The use of micellar electrokinetic chromatography (MEKC) for studying the hydrophobic character of modified Monomethyl Auristatin E derivatives, as Novel Candidates for the Design of Antibody–Drug Conjugates, which are promising state-of-the-art biopharmaceutical drugs for selective drug-delivery applications and the treatment of diseases such as cancer. 9. The use of recycled diatomaceous earth as the extraction phase in solid phase microextraction (SPME) technique for the determination of polycyclic aromatic hydrocarbons (PAHs) in river water samples, with separation/detection performed by gas chromatography-mass spectrometry (GC-MS).
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spelling doab-20.500.12854ir-689702024-03-27T16:34:28Z Five Years of Separations Samanidou, Victoria Lucena, Rafael recycled diatomaceous earth solid phase microextraction polycyclic aromatic hydrocarbons gas chromatography-mass spectrometry antibody-drug conjugate biopharmaceutical cytotoxicity hydrophobicity micellar electrokinetic chromatography tandem mass spectrometry linear ion trap glycolipid diacyltrehalose Mycobacterium tuberculosis bisphosphonates risedronate zoledronate tiludronate ZIC-HILIC PDA quantitation tablets ionic liquid stationary phase gas chromatography chromatographic selectivity alkylated polycyclic aromatic hydrocarbons (alkylated PAHs) diphenylamine gunshot residues hands dry cotton swab in-tube solid-phase extraction capillary liquid chromatography SEM-EDX thyroid dissolution liquid chromatography-mass spectrometry membrane filtration-treatment membrane type-operation membrane fouling mechanism tannery industrial wastewater vibratory shear-enhanced process (VSEP) tricyclic antidepressants (TCAs) sample treatment biological fluids UV filters matrix solid-phase dispersion μ-MSPD miniaturized extraction technique GC–MS/MS cosmetic analysis personal care products fragrance allergens preservatives plasticizers synthetic musks thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general Five years of Separations are celebrated by a collection of ten feature articles: one review and nine research articles on topics of current interest. Applications of Gas Chromatography for the Analysis of Tricyclic Antidepressants in Biological Matrices are presented focusing on novel extraction techniques and novel materials used for sample preparation due to the great demand for method development for the determination of TCAs in biofluids, especially for therapeutic drug monitoring. Original research articles include the following: 1. Insights into the Mechanism of Separation of Bisphosphonates by Zwitterionic Hydrophilic Interaction Liquid Chromatography: Application to the Quantitation of Risedronate in Pharmaceuticals. 2. A method based on micro-matrix solid-phase dispersion (μ-MSPD) followed by gas-chromatography tandem mass spectrometry (GC–MS/MS), developed to analyze UV filters in personal care products. 3. The performance of a vibratory shear-enhanced process (VSEP) combined with an appropriate membrane unit for the treatment of simulated or industrial tannery wastewaters. 4. A method for the analysis of thyroid hormones by liquid chromatography-mass spectrometry that was used for the dissolution testing of single- and dual-component thyroid hormone supplements via a two-stage biorelevant dissolution procedure. 5. A method involving the collection and determination of organic and inorganic gunshot residues on hands using online in-tube solid-phase microextraction (IT-SPME) coupled to miniaturized capillary liquid chromatography with diode array detection (CapLC-DAD) and scanning electron microscopy coupled to energy dispersion X-ray (SEM-EDX), respectively, for quantifying both residues. 6. The gas chromatographic retention behavior of 16 polycyclic aromatic hydrocarbons (PAHs) and alkylated PAHs on a new ionic liquid stationary phase, 1,12-di(tripropylphosphonium) dodecane bis(trifluoromethanesulfonyl)imide (SLB®-ILPAH) intended for the separation of PAH mixtures, which was compared with the elution pattern on more traditional stationary phases: a non-polar phenyl arylene (DB-5ms) and a semipolar 50% phenyl dimethyl siloxane (SLB PAHms) column. 7. The Multiple-Stage Precursor Ion Separation and High Resolution Mass Spectrometry toward Structural Characterization of 2,3-Diacyltrehalose Family from Mycobacterium tuberculosis 8. The use of micellar electrokinetic chromatography (MEKC) for studying the hydrophobic character of modified Monomethyl Auristatin E derivatives, as Novel Candidates for the Design of Antibody–Drug Conjugates, which are promising state-of-the-art biopharmaceutical drugs for selective drug-delivery applications and the treatment of diseases such as cancer. 9. The use of recycled diatomaceous earth as the extraction phase in solid phase microextraction (SPME) technique for the determination of polycyclic aromatic hydrocarbons (PAHs) in river water samples, with separation/detection performed by gas chromatography-mass spectrometry (GC-MS). 2021-05-01T15:34:26Z 2021-05-01T15:34:26Z 2020 book ONIX_20210501_9783039369249_716 9783039369249 9783039369256 https://directory.doabooks.org/handle/20.500.12854/68970 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/2738 https://mdpi.com/books/pdfview/book/2738 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-03936-925-6 10.3390/books978-3-03936-925-6 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783039369249 9783039369256 152 Basel, Switzerland open access
spellingShingle recycled diatomaceous earth
solid phase microextraction
polycyclic aromatic hydrocarbons
gas chromatography-mass spectrometry
antibody-drug conjugate
biopharmaceutical
cytotoxicity
hydrophobicity
micellar electrokinetic chromatography
tandem mass spectrometry
linear ion trap
glycolipid
diacyltrehalose
Mycobacterium tuberculosis
bisphosphonates
risedronate
zoledronate
tiludronate
ZIC-HILIC
PDA
quantitation
tablets
ionic liquid stationary phase
gas chromatography
chromatographic selectivity
alkylated polycyclic aromatic hydrocarbons (alkylated PAHs)
diphenylamine
gunshot residues
hands
dry cotton swab
in-tube solid-phase extraction
capillary liquid chromatography
SEM-EDX
thyroid
dissolution
liquid chromatography-mass spectrometry
membrane filtration-treatment
membrane type-operation
membrane fouling mechanism
tannery industrial wastewater
vibratory shear-enhanced process (VSEP)
tricyclic antidepressants (TCAs)
sample treatment
biological fluids
UV filters
matrix solid-phase dispersion
μ-MSPD
miniaturized extraction technique
GC–MS/MS
cosmetic analysis
personal care products
fragrance allergens
preservatives
plasticizers
synthetic musks
thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
Five Years of Separations
title Five Years of Separations
title_full Five Years of Separations
title_fullStr Five Years of Separations
title_full_unstemmed Five Years of Separations
title_short Five Years of Separations
title_sort five years of separations
topic recycled diatomaceous earth
solid phase microextraction
polycyclic aromatic hydrocarbons
gas chromatography-mass spectrometry
antibody-drug conjugate
biopharmaceutical
cytotoxicity
hydrophobicity
micellar electrokinetic chromatography
tandem mass spectrometry
linear ion trap
glycolipid
diacyltrehalose
Mycobacterium tuberculosis
bisphosphonates
risedronate
zoledronate
tiludronate
ZIC-HILIC
PDA
quantitation
tablets
ionic liquid stationary phase
gas chromatography
chromatographic selectivity
alkylated polycyclic aromatic hydrocarbons (alkylated PAHs)
diphenylamine
gunshot residues
hands
dry cotton swab
in-tube solid-phase extraction
capillary liquid chromatography
SEM-EDX
thyroid
dissolution
liquid chromatography-mass spectrometry
membrane filtration-treatment
membrane type-operation
membrane fouling mechanism
tannery industrial wastewater
vibratory shear-enhanced process (VSEP)
tricyclic antidepressants (TCAs)
sample treatment
biological fluids
UV filters
matrix solid-phase dispersion
μ-MSPD
miniaturized extraction technique
GC–MS/MS
cosmetic analysis
personal care products
fragrance allergens
preservatives
plasticizers
synthetic musks
thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
topic_facet recycled diatomaceous earth
solid phase microextraction
polycyclic aromatic hydrocarbons
gas chromatography-mass spectrometry
antibody-drug conjugate
biopharmaceutical
cytotoxicity
hydrophobicity
micellar electrokinetic chromatography
tandem mass spectrometry
linear ion trap
glycolipid
diacyltrehalose
Mycobacterium tuberculosis
bisphosphonates
risedronate
zoledronate
tiludronate
ZIC-HILIC
PDA
quantitation
tablets
ionic liquid stationary phase
gas chromatography
chromatographic selectivity
alkylated polycyclic aromatic hydrocarbons (alkylated PAHs)
diphenylamine
gunshot residues
hands
dry cotton swab
in-tube solid-phase extraction
capillary liquid chromatography
SEM-EDX
thyroid
dissolution
liquid chromatography-mass spectrometry
membrane filtration-treatment
membrane type-operation
membrane fouling mechanism
tannery industrial wastewater
vibratory shear-enhanced process (VSEP)
tricyclic antidepressants (TCAs)
sample treatment
biological fluids
UV filters
matrix solid-phase dispersion
μ-MSPD
miniaturized extraction technique
GC–MS/MS
cosmetic analysis
personal care products
fragrance allergens
preservatives
plasticizers
synthetic musks
thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
url ONIX_20210501_9783039369249_716