Microbial Virulence Factors
Microbial virulence factors encompass a wide range of molecules produced by pathogenic microorganisms, enhancing their ability to evade their host defenses and cause disease. This broad definition comprises secreted products such as toxins, enzymes, exopolysaccharides, as well as cell surface struct...
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| Materiálatiipa: | Online |
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| Giella: | eaŋgalasgiella |
| Almmustuhtton: |
MDPI - Multidisciplinary Digital Publishing Institute
2021
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| Fáttát: | |
| Liŋkkat: | ONIX_20210501_9783039369461_787 |
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| _version_ | 1869522131905150976 |
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| collection | Directory of Open Access Books |
| description | Microbial virulence factors encompass a wide range of molecules produced by pathogenic microorganisms, enhancing their ability to evade their host defenses and cause disease. This broad definition comprises secreted products such as toxins, enzymes, exopolysaccharides, as well as cell surface structures such as capsules, lipopolysaccharides, glyco- and lipoproteins. Intracellular changes in metabolic regulatory networks, governed by protein sensors/regulators and non-coding regulatory RNAs, are also known to contribute to virulence. Furthermore, some secreted microbial products have the ability to enter the host cell and manipulate their machinery, contributing to the success of the infection. The knowledge, at the molecular level, of the biology of microbial pathogens and their virulence factors is central in the development of novel therapeutic molecules and strategies to combat microbial infections. The present collection comprises state of the art research and review papers on virulence factors and mechanisms of a wide range of bacterial and fungal pathogens for humans, animals, and plants, thus reflecting the impact of microorganisms in health and economic human activities, and the importance of the topic. |
| format | Online |
| id | doab-20.500.12854ir-69041 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-690412024-03-28T03:33:34Z Microbial Virulence Factors Leitão, Jorge H. Aeromonas hydrophila LysR-family ΔlahS global regulator virulence Sclerotinia sclerotiorum SsNsd1 compound appressorium two-dimensional electrophoresis proteomics analysis differential expression proteins cystic fibrosis Pseudomonas aeruginosa Burkholderia cepacia complex small noncoding regulatory RNAs pathogenicity usg truA Salmonella enterica serovar Typhimurium oxidative stress intracellular survival pathogenomics coagulase-negative staphylococci virulence factors whole genome sequencing autotransporter covalent labeling bacterial surface protein SpyCatcher topology mapping virulence factor Candida host-pathogen interaction biofilm formation morphology immune evasion Trueperella pyogenes pyolysin infection immune response Actinomycetales Bordetella pertussis Hfq omics analysis T3SS serum resistance solute-binding proteins phytoplasma effector protein apple apple proliferation bacteria blood–brain barrier blood–cerebrospinal fluid barrier meningitis outer membrane vesicles (OMVs) Candida albicans antimicrobial peptides complement interspecies interactions inter-kingdom protection fungicidal activity fluconazole hyphae antimicrobial peptide EDTA primary ciliary dyskinesia anti-virulence sputum chronic infection Enterobacterales Klebsiella Enterobacter Citrobacter antibiotic resistance biofilm SPATEs UTIs cytotoxicity serine proteases 5637 bladder cells mucin gelatin actin protease Lon Dickeya solani plant pathogen motility type III secretion system resistance to stress lon expression pectinolytic enzymes gene expression manipulation inflammation persistence replicative niche actin proteolysis metalloproteinases protease ECP 32 grimelysin protealysin bacterial invasion microbial virulence factors bacterial pathogens fungal pathogens thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences Microbial virulence factors encompass a wide range of molecules produced by pathogenic microorganisms, enhancing their ability to evade their host defenses and cause disease. This broad definition comprises secreted products such as toxins, enzymes, exopolysaccharides, as well as cell surface structures such as capsules, lipopolysaccharides, glyco- and lipoproteins. Intracellular changes in metabolic regulatory networks, governed by protein sensors/regulators and non-coding regulatory RNAs, are also known to contribute to virulence. Furthermore, some secreted microbial products have the ability to enter the host cell and manipulate their machinery, contributing to the success of the infection. The knowledge, at the molecular level, of the biology of microbial pathogens and their virulence factors is central in the development of novel therapeutic molecules and strategies to combat microbial infections. The present collection comprises state of the art research and review papers on virulence factors and mechanisms of a wide range of bacterial and fungal pathogens for humans, animals, and plants, thus reflecting the impact of microorganisms in health and economic human activities, and the importance of the topic. 2021-05-01T15:36:00Z 2021-05-01T15:36:00Z 2020 book ONIX_20210501_9783039369461_787 9783039369461 9783039369478 https://directory.doabooks.org/handle/20.500.12854/69041 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/2810 https://mdpi.com/books/pdfview/book/2810 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-03936-947-8 10.3390/books978-3-03936-947-8 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783039369461 9783039369478 400 Basel, Switzerland open access |
| spellingShingle | Aeromonas hydrophila LysR-family ΔlahS global regulator virulence Sclerotinia sclerotiorum SsNsd1 compound appressorium two-dimensional electrophoresis proteomics analysis differential expression proteins cystic fibrosis Pseudomonas aeruginosa Burkholderia cepacia complex small noncoding regulatory RNAs pathogenicity usg truA Salmonella enterica serovar Typhimurium oxidative stress intracellular survival pathogenomics coagulase-negative staphylococci virulence factors whole genome sequencing autotransporter covalent labeling bacterial surface protein SpyCatcher topology mapping virulence factor Candida host-pathogen interaction biofilm formation morphology immune evasion Trueperella pyogenes pyolysin infection immune response Actinomycetales Bordetella pertussis Hfq omics analysis T3SS serum resistance solute-binding proteins phytoplasma effector protein apple apple proliferation bacteria blood–brain barrier blood–cerebrospinal fluid barrier meningitis outer membrane vesicles (OMVs) Candida albicans antimicrobial peptides complement interspecies interactions inter-kingdom protection fungicidal activity fluconazole hyphae antimicrobial peptide EDTA primary ciliary dyskinesia anti-virulence sputum chronic infection Enterobacterales Klebsiella Enterobacter Citrobacter antibiotic resistance biofilm SPATEs UTIs cytotoxicity serine proteases 5637 bladder cells mucin gelatin actin protease Lon Dickeya solani plant pathogen motility type III secretion system resistance to stress lon expression pectinolytic enzymes gene expression manipulation inflammation persistence replicative niche actin proteolysis metalloproteinases protease ECP 32 grimelysin protealysin bacterial invasion microbial virulence factors bacterial pathogens fungal pathogens thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences Microbial Virulence Factors |
| title | Microbial Virulence Factors |
| title_full | Microbial Virulence Factors |
| title_fullStr | Microbial Virulence Factors |
| title_full_unstemmed | Microbial Virulence Factors |
| title_short | Microbial Virulence Factors |
| title_sort | microbial virulence factors |
| topic | Aeromonas hydrophila LysR-family ΔlahS global regulator virulence Sclerotinia sclerotiorum SsNsd1 compound appressorium two-dimensional electrophoresis proteomics analysis differential expression proteins cystic fibrosis Pseudomonas aeruginosa Burkholderia cepacia complex small noncoding regulatory RNAs pathogenicity usg truA Salmonella enterica serovar Typhimurium oxidative stress intracellular survival pathogenomics coagulase-negative staphylococci virulence factors whole genome sequencing autotransporter covalent labeling bacterial surface protein SpyCatcher topology mapping virulence factor Candida host-pathogen interaction biofilm formation morphology immune evasion Trueperella pyogenes pyolysin infection immune response Actinomycetales Bordetella pertussis Hfq omics analysis T3SS serum resistance solute-binding proteins phytoplasma effector protein apple apple proliferation bacteria blood–brain barrier blood–cerebrospinal fluid barrier meningitis outer membrane vesicles (OMVs) Candida albicans antimicrobial peptides complement interspecies interactions inter-kingdom protection fungicidal activity fluconazole hyphae antimicrobial peptide EDTA primary ciliary dyskinesia anti-virulence sputum chronic infection Enterobacterales Klebsiella Enterobacter Citrobacter antibiotic resistance biofilm SPATEs UTIs cytotoxicity serine proteases 5637 bladder cells mucin gelatin actin protease Lon Dickeya solani plant pathogen motility type III secretion system resistance to stress lon expression pectinolytic enzymes gene expression manipulation inflammation persistence replicative niche actin proteolysis metalloproteinases protease ECP 32 grimelysin protealysin bacterial invasion microbial virulence factors bacterial pathogens fungal pathogens thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences |
| topic_facet | Aeromonas hydrophila LysR-family ΔlahS global regulator virulence Sclerotinia sclerotiorum SsNsd1 compound appressorium two-dimensional electrophoresis proteomics analysis differential expression proteins cystic fibrosis Pseudomonas aeruginosa Burkholderia cepacia complex small noncoding regulatory RNAs pathogenicity usg truA Salmonella enterica serovar Typhimurium oxidative stress intracellular survival pathogenomics coagulase-negative staphylococci virulence factors whole genome sequencing autotransporter covalent labeling bacterial surface protein SpyCatcher topology mapping virulence factor Candida host-pathogen interaction biofilm formation morphology immune evasion Trueperella pyogenes pyolysin infection immune response Actinomycetales Bordetella pertussis Hfq omics analysis T3SS serum resistance solute-binding proteins phytoplasma effector protein apple apple proliferation bacteria blood–brain barrier blood–cerebrospinal fluid barrier meningitis outer membrane vesicles (OMVs) Candida albicans antimicrobial peptides complement interspecies interactions inter-kingdom protection fungicidal activity fluconazole hyphae antimicrobial peptide EDTA primary ciliary dyskinesia anti-virulence sputum chronic infection Enterobacterales Klebsiella Enterobacter Citrobacter antibiotic resistance biofilm SPATEs UTIs cytotoxicity serine proteases 5637 bladder cells mucin gelatin actin protease Lon Dickeya solani plant pathogen motility type III secretion system resistance to stress lon expression pectinolytic enzymes gene expression manipulation inflammation persistence replicative niche actin proteolysis metalloproteinases protease ECP 32 grimelysin protealysin bacterial invasion microbial virulence factors bacterial pathogens fungal pathogens thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences |
| url | ONIX_20210501_9783039369461_787 |