Toxicological Effects of Mycotoxins on Target Cells
Mycotoxins are a Public Health concern that in last year have reached the top 10 food and product hazard categories in the Rapid Alert System for Food and Feed (RASFF), with almost six hundred notifications. The toxicological effects of mycotoxins are evaluated through the extrapolation of results f...
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| フォーマット: | Online |
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| 言語: | 英語 |
| 出版事項: |
MDPI - Multidisciplinary Digital Publishing Institute
2021
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| 主題: | |
| オンライン・アクセス: | ONIX_20210501_9783039369263_814 |
| タグ: |
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| _version_ | 1869523544378966016 |
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| collection | Directory of Open Access Books |
| description | Mycotoxins are a Public Health concern that in last year have reached the top 10 food and product hazard categories in the Rapid Alert System for Food and Feed (RASFF), with almost six hundred notifications. The toxicological effects of mycotoxins are evaluated through the extrapolation of results from in vivo and in vitro assays. Studies of mycotoxins’ effects at the cellular level precede those in organs and systems. All these studies are key steps for risk assessment and following legislation for mycotoxins. This Special Issue of Toxins comprises 10 original contributions and two reviews. The Issue reports new findings regarding toxic mechanisms, the use of innovative techniques to study the potential toxicity of mycotoxins not only individually but in combination, reflecting a real scenario according to current studies of mycotoxins. |
| format | Online |
| id | doab-20.500.12854ir-69068 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-690682024-03-31T13:09:33Z Toxicological Effects of Mycotoxins on Target Cells Juan-García, Ana Destruxin A Bombyx mori binding protein BmTudor-sn Bm12 cell Ochratoxin A (OTA) human Stem Cells mycotoxins cells cytotoxicity cell culture T-2 toxin HT-2 toxin apoptosis autophagy endophyte fungi neurotoxin lolitrems ochratoxin A beauvericin mixtures HepG2 cells genotoxicity cell cycle Fusarium Aspergillus Penicillium Alternaria emerging mycotoxin in vitro IPEC-J2 occurrence data trichothecene biosynthetic pathway acetyltransferase deacetylase deoxynivalenol 3-acetyldeoxynivalenol isotrichodermol isotrichodermin differentiated Caco-2 cells cell apoptosis transcriptome analysis hepatocyte chicken acute toxicity combined toxicity cell protection silibinin in silico prediction co-culture models mycotoxin interaction Loewe additivity combination index isobologram Chou-Talalay method MixLow IPEC-J2 cells RNA-seq inflammation MAPKs n/a thema EDItEUR::M Medicine and Nursing Mycotoxins are a Public Health concern that in last year have reached the top 10 food and product hazard categories in the Rapid Alert System for Food and Feed (RASFF), with almost six hundred notifications. The toxicological effects of mycotoxins are evaluated through the extrapolation of results from in vivo and in vitro assays. Studies of mycotoxins’ effects at the cellular level precede those in organs and systems. All these studies are key steps for risk assessment and following legislation for mycotoxins. This Special Issue of Toxins comprises 10 original contributions and two reviews. The Issue reports new findings regarding toxic mechanisms, the use of innovative techniques to study the potential toxicity of mycotoxins not only individually but in combination, reflecting a real scenario according to current studies of mycotoxins. 2021-05-01T15:40:24Z 2021-05-01T15:40:24Z 2020 book ONIX_20210501_9783039369263_814 9783039369263 9783039369270 https://directory.doabooks.org/handle/20.500.12854/69068 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/2837 https://mdpi.com/books/pdfview/book/2837 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-03936-927-0 10.3390/books978-3-03936-927-0 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783039369263 9783039369270 218 Basel, Switzerland open access |
| spellingShingle | Destruxin A Bombyx mori binding protein BmTudor-sn Bm12 cell Ochratoxin A (OTA) human Stem Cells mycotoxins cells cytotoxicity cell culture T-2 toxin HT-2 toxin apoptosis autophagy endophyte fungi neurotoxin lolitrems ochratoxin A beauvericin mixtures HepG2 cells genotoxicity cell cycle Fusarium Aspergillus Penicillium Alternaria emerging mycotoxin in vitro IPEC-J2 occurrence data trichothecene biosynthetic pathway acetyltransferase deacetylase deoxynivalenol 3-acetyldeoxynivalenol isotrichodermol isotrichodermin differentiated Caco-2 cells cell apoptosis transcriptome analysis hepatocyte chicken acute toxicity combined toxicity cell protection silibinin in silico prediction co-culture models mycotoxin interaction Loewe additivity combination index isobologram Chou-Talalay method MixLow IPEC-J2 cells RNA-seq inflammation MAPKs n/a thema EDItEUR::M Medicine and Nursing Toxicological Effects of Mycotoxins on Target Cells |
| title | Toxicological Effects of Mycotoxins on Target Cells |
| title_full | Toxicological Effects of Mycotoxins on Target Cells |
| title_fullStr | Toxicological Effects of Mycotoxins on Target Cells |
| title_full_unstemmed | Toxicological Effects of Mycotoxins on Target Cells |
| title_short | Toxicological Effects of Mycotoxins on Target Cells |
| title_sort | toxicological effects of mycotoxins on target cells |
| topic | Destruxin A Bombyx mori binding protein BmTudor-sn Bm12 cell Ochratoxin A (OTA) human Stem Cells mycotoxins cells cytotoxicity cell culture T-2 toxin HT-2 toxin apoptosis autophagy endophyte fungi neurotoxin lolitrems ochratoxin A beauvericin mixtures HepG2 cells genotoxicity cell cycle Fusarium Aspergillus Penicillium Alternaria emerging mycotoxin in vitro IPEC-J2 occurrence data trichothecene biosynthetic pathway acetyltransferase deacetylase deoxynivalenol 3-acetyldeoxynivalenol isotrichodermol isotrichodermin differentiated Caco-2 cells cell apoptosis transcriptome analysis hepatocyte chicken acute toxicity combined toxicity cell protection silibinin in silico prediction co-culture models mycotoxin interaction Loewe additivity combination index isobologram Chou-Talalay method MixLow IPEC-J2 cells RNA-seq inflammation MAPKs n/a thema EDItEUR::M Medicine and Nursing |
| topic_facet | Destruxin A Bombyx mori binding protein BmTudor-sn Bm12 cell Ochratoxin A (OTA) human Stem Cells mycotoxins cells cytotoxicity cell culture T-2 toxin HT-2 toxin apoptosis autophagy endophyte fungi neurotoxin lolitrems ochratoxin A beauvericin mixtures HepG2 cells genotoxicity cell cycle Fusarium Aspergillus Penicillium Alternaria emerging mycotoxin in vitro IPEC-J2 occurrence data trichothecene biosynthetic pathway acetyltransferase deacetylase deoxynivalenol 3-acetyldeoxynivalenol isotrichodermol isotrichodermin differentiated Caco-2 cells cell apoptosis transcriptome analysis hepatocyte chicken acute toxicity combined toxicity cell protection silibinin in silico prediction co-culture models mycotoxin interaction Loewe additivity combination index isobologram Chou-Talalay method MixLow IPEC-J2 cells RNA-seq inflammation MAPKs n/a thema EDItEUR::M Medicine and Nursing |
| url | ONIX_20210501_9783039369263_814 |