Toxicological Effects of Mycotoxins on Target Cells

Mycotoxins are a Public Health concern that in last year have reached the top 10 food and product hazard categories in the Rapid Alert System for Food and Feed (RASFF), with almost six hundred notifications. The toxicological effects of mycotoxins are evaluated through the extrapolation of results f...

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出版事項: MDPI - Multidisciplinary Digital Publishing Institute 2021
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collection Directory of Open Access Books
description Mycotoxins are a Public Health concern that in last year have reached the top 10 food and product hazard categories in the Rapid Alert System for Food and Feed (RASFF), with almost six hundred notifications. The toxicological effects of mycotoxins are evaluated through the extrapolation of results from in vivo and in vitro assays. Studies of mycotoxins’ effects at the cellular level precede those in organs and systems. All these studies are key steps for risk assessment and following legislation for mycotoxins. This Special Issue of Toxins comprises 10 original contributions and two reviews. The Issue reports new findings regarding toxic mechanisms, the use of innovative techniques to study the potential toxicity of mycotoxins not only individually but in combination, reflecting a real scenario according to current studies of mycotoxins.
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publisherStr MDPI - Multidisciplinary Digital Publishing Institute
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spelling doab-20.500.12854ir-690682024-03-31T13:09:33Z Toxicological Effects of Mycotoxins on Target Cells Juan-García, Ana Destruxin A Bombyx mori binding protein BmTudor-sn Bm12 cell Ochratoxin A (OTA) human Stem Cells mycotoxins cells cytotoxicity cell culture T-2 toxin HT-2 toxin apoptosis autophagy endophyte fungi neurotoxin lolitrems ochratoxin A beauvericin mixtures HepG2 cells genotoxicity cell cycle Fusarium Aspergillus Penicillium Alternaria emerging mycotoxin in vitro IPEC-J2 occurrence data trichothecene biosynthetic pathway acetyltransferase deacetylase deoxynivalenol 3-acetyldeoxynivalenol isotrichodermol isotrichodermin differentiated Caco-2 cells cell apoptosis transcriptome analysis hepatocyte chicken acute toxicity combined toxicity cell protection silibinin in silico prediction co-culture models mycotoxin interaction Loewe additivity combination index isobologram Chou-Talalay method MixLow IPEC-J2 cells RNA-seq inflammation MAPKs n/a thema EDItEUR::M Medicine and Nursing Mycotoxins are a Public Health concern that in last year have reached the top 10 food and product hazard categories in the Rapid Alert System for Food and Feed (RASFF), with almost six hundred notifications. The toxicological effects of mycotoxins are evaluated through the extrapolation of results from in vivo and in vitro assays. Studies of mycotoxins’ effects at the cellular level precede those in organs and systems. All these studies are key steps for risk assessment and following legislation for mycotoxins. This Special Issue of Toxins comprises 10 original contributions and two reviews. The Issue reports new findings regarding toxic mechanisms, the use of innovative techniques to study the potential toxicity of mycotoxins not only individually but in combination, reflecting a real scenario according to current studies of mycotoxins. 2021-05-01T15:40:24Z 2021-05-01T15:40:24Z 2020 book ONIX_20210501_9783039369263_814 9783039369263 9783039369270 https://directory.doabooks.org/handle/20.500.12854/69068 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/2837 https://mdpi.com/books/pdfview/book/2837 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-03936-927-0 10.3390/books978-3-03936-927-0 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783039369263 9783039369270 218 Basel, Switzerland open access
spellingShingle Destruxin A
Bombyx mori
binding protein
BmTudor-sn
Bm12 cell
Ochratoxin A (OTA)
human Stem Cells
mycotoxins
cells
cytotoxicity
cell culture
T-2 toxin
HT-2 toxin
apoptosis
autophagy
endophyte
fungi
neurotoxin
lolitrems
ochratoxin A
beauvericin
mixtures
HepG2 cells
genotoxicity
cell cycle
Fusarium
Aspergillus
Penicillium
Alternaria
emerging mycotoxin
in vitro
IPEC-J2
occurrence data
trichothecene
biosynthetic pathway
acetyltransferase
deacetylase
deoxynivalenol
3-acetyldeoxynivalenol
isotrichodermol
isotrichodermin
differentiated Caco-2 cells
cell apoptosis
transcriptome analysis
hepatocyte
chicken
acute toxicity
combined toxicity
cell protection
silibinin
in silico prediction
co-culture models
mycotoxin interaction
Loewe additivity
combination index
isobologram
Chou-Talalay method
MixLow
IPEC-J2 cells
RNA-seq
inflammation
MAPKs
n/a
thema EDItEUR::M Medicine and Nursing
Toxicological Effects of Mycotoxins on Target Cells
title Toxicological Effects of Mycotoxins on Target Cells
title_full Toxicological Effects of Mycotoxins on Target Cells
title_fullStr Toxicological Effects of Mycotoxins on Target Cells
title_full_unstemmed Toxicological Effects of Mycotoxins on Target Cells
title_short Toxicological Effects of Mycotoxins on Target Cells
title_sort toxicological effects of mycotoxins on target cells
topic Destruxin A
Bombyx mori
binding protein
BmTudor-sn
Bm12 cell
Ochratoxin A (OTA)
human Stem Cells
mycotoxins
cells
cytotoxicity
cell culture
T-2 toxin
HT-2 toxin
apoptosis
autophagy
endophyte
fungi
neurotoxin
lolitrems
ochratoxin A
beauvericin
mixtures
HepG2 cells
genotoxicity
cell cycle
Fusarium
Aspergillus
Penicillium
Alternaria
emerging mycotoxin
in vitro
IPEC-J2
occurrence data
trichothecene
biosynthetic pathway
acetyltransferase
deacetylase
deoxynivalenol
3-acetyldeoxynivalenol
isotrichodermol
isotrichodermin
differentiated Caco-2 cells
cell apoptosis
transcriptome analysis
hepatocyte
chicken
acute toxicity
combined toxicity
cell protection
silibinin
in silico prediction
co-culture models
mycotoxin interaction
Loewe additivity
combination index
isobologram
Chou-Talalay method
MixLow
IPEC-J2 cells
RNA-seq
inflammation
MAPKs
n/a
thema EDItEUR::M Medicine and Nursing
topic_facet Destruxin A
Bombyx mori
binding protein
BmTudor-sn
Bm12 cell
Ochratoxin A (OTA)
human Stem Cells
mycotoxins
cells
cytotoxicity
cell culture
T-2 toxin
HT-2 toxin
apoptosis
autophagy
endophyte
fungi
neurotoxin
lolitrems
ochratoxin A
beauvericin
mixtures
HepG2 cells
genotoxicity
cell cycle
Fusarium
Aspergillus
Penicillium
Alternaria
emerging mycotoxin
in vitro
IPEC-J2
occurrence data
trichothecene
biosynthetic pathway
acetyltransferase
deacetylase
deoxynivalenol
3-acetyldeoxynivalenol
isotrichodermol
isotrichodermin
differentiated Caco-2 cells
cell apoptosis
transcriptome analysis
hepatocyte
chicken
acute toxicity
combined toxicity
cell protection
silibinin
in silico prediction
co-culture models
mycotoxin interaction
Loewe additivity
combination index
isobologram
Chou-Talalay method
MixLow
IPEC-J2 cells
RNA-seq
inflammation
MAPKs
n/a
thema EDItEUR::M Medicine and Nursing
url ONIX_20210501_9783039369263_814