Virus-Like Particle Vaccines

The structure, uniformity, stability, and functions of virus-like particles (VLPs) have encouraged scientists to utilize them as a unique tool in various applications in biomedical fields. Their interaction with the innate immune system is of major importance for the adaptive immune response they in...

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collection Directory of Open Access Books
description The structure, uniformity, stability, and functions of virus-like particles (VLPs) have encouraged scientists to utilize them as a unique tool in various applications in biomedical fields. Their interaction with the innate immune system is of major importance for the adaptive immune response they induce. The innate immune cells and molecules recognize and interact with VLPs on the basis of two major characteristics: size and surface geometry. VLP-based vaccines against hepatitis B, human papilloma, malaria, and hepatitis E have been developed and are available in many countries around the world. Given the inherent immunogenicity of VLPs, they render themselves ideal for the development of new vaccines against infectious diseases as well as noncommunicable diseases, such as chronic inflammation or cancer. This Special Issue is designed to provide an up-to-date view of the latest progress in the development of VLP-based prophylactic and therapeutic vaccines and technologies for their generation.
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publisherStr MDPI - Multidisciplinary Digital Publishing Institute
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spelling doab-20.500.12854ir-690862024-04-01T23:19:19Z Virus-Like Particle Vaccines Bachmann, Martin F Vogel, Monique virus-like particle influenza A(H1N1)pdm09 vaccination pregnant women antibody titers norovirus VLP vaccine genotype pre-existing immunity cross-reactivity blocking antibodies original antigenic sin (OAS) HPVs vaccines virus-like particles (VLPs) minor capsid protein (L2) HCMV cytomegalovirus nanoparticle immune response Sudan virus mice horse purified IgG long-lived plasma cells antibodies multivalency virus-like particles antigenic analysis epitope characterization hepatitis E vaccine serological evaluation virion-like epitopes well-characterized vaccines hepatitis B virus surface (envelope) antigen sub-viral particle capsid antigen display platform viral quantification NTA flow virometry SRFM cryo-TEM SEM plant virus virus-like vaccine platform epitope antigen cat allergy Fel d 1 HypoCat™ IL-13 interleukin-13 Tfh cells cancer immunotherapy H7N9 pandemic influenza A avian flu IAV VLP vaccine n/a thema EDItEUR::N History and Archaeology::NH History thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBF Social and ethical issues The structure, uniformity, stability, and functions of virus-like particles (VLPs) have encouraged scientists to utilize them as a unique tool in various applications in biomedical fields. Their interaction with the innate immune system is of major importance for the adaptive immune response they induce. The innate immune cells and molecules recognize and interact with VLPs on the basis of two major characteristics: size and surface geometry. VLP-based vaccines against hepatitis B, human papilloma, malaria, and hepatitis E have been developed and are available in many countries around the world. Given the inherent immunogenicity of VLPs, they render themselves ideal for the development of new vaccines against infectious diseases as well as noncommunicable diseases, such as chronic inflammation or cancer. This Special Issue is designed to provide an up-to-date view of the latest progress in the development of VLP-based prophylactic and therapeutic vaccines and technologies for their generation. 2021-05-01T15:40:48Z 2021-05-01T15:40:48Z 2020 book ONIX_20210501_9783039430741_832 9783039430741 9783039430758 https://directory.doabooks.org/handle/20.500.12854/69086 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/2855 https://mdpi.com/books/pdfview/book/2855 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-03943-075-8 10.3390/books978-3-03943-075-8 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783039430741 9783039430758 262 Basel, Switzerland open access
spellingShingle virus-like particle
influenza A(H1N1)pdm09
vaccination
pregnant women
antibody titers
norovirus
VLP
vaccine
genotype
pre-existing immunity
cross-reactivity
blocking antibodies
original antigenic sin (OAS)
HPVs
vaccines
virus-like particles (VLPs)
minor capsid protein (L2)
HCMV
cytomegalovirus
nanoparticle
immune response
Sudan virus
mice
horse
purified IgG
long-lived plasma cells
antibodies
multivalency
virus-like particles
antigenic analysis
epitope characterization
hepatitis E vaccine
serological evaluation
virion-like epitopes
well-characterized vaccines
hepatitis B virus
surface (envelope) antigen
sub-viral particle
capsid
antigen display
platform
viral quantification
NTA
flow virometry
SRFM
cryo-TEM
SEM
plant virus
virus-like
vaccine platform
epitope
antigen
cat allergy
Fel d 1
HypoCat™
IL-13
interleukin-13
Tfh cells
cancer
immunotherapy
H7N9
pandemic influenza A
avian flu
IAV
VLP vaccine
n/a
thema EDItEUR::N History and Archaeology::NH History
thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBF Social and ethical issues
Virus-Like Particle Vaccines
title Virus-Like Particle Vaccines
title_full Virus-Like Particle Vaccines
title_fullStr Virus-Like Particle Vaccines
title_full_unstemmed Virus-Like Particle Vaccines
title_short Virus-Like Particle Vaccines
title_sort virus like particle vaccines
topic virus-like particle
influenza A(H1N1)pdm09
vaccination
pregnant women
antibody titers
norovirus
VLP
vaccine
genotype
pre-existing immunity
cross-reactivity
blocking antibodies
original antigenic sin (OAS)
HPVs
vaccines
virus-like particles (VLPs)
minor capsid protein (L2)
HCMV
cytomegalovirus
nanoparticle
immune response
Sudan virus
mice
horse
purified IgG
long-lived plasma cells
antibodies
multivalency
virus-like particles
antigenic analysis
epitope characterization
hepatitis E vaccine
serological evaluation
virion-like epitopes
well-characterized vaccines
hepatitis B virus
surface (envelope) antigen
sub-viral particle
capsid
antigen display
platform
viral quantification
NTA
flow virometry
SRFM
cryo-TEM
SEM
plant virus
virus-like
vaccine platform
epitope
antigen
cat allergy
Fel d 1
HypoCat™
IL-13
interleukin-13
Tfh cells
cancer
immunotherapy
H7N9
pandemic influenza A
avian flu
IAV
VLP vaccine
n/a
thema EDItEUR::N History and Archaeology::NH History
thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBF Social and ethical issues
topic_facet virus-like particle
influenza A(H1N1)pdm09
vaccination
pregnant women
antibody titers
norovirus
VLP
vaccine
genotype
pre-existing immunity
cross-reactivity
blocking antibodies
original antigenic sin (OAS)
HPVs
vaccines
virus-like particles (VLPs)
minor capsid protein (L2)
HCMV
cytomegalovirus
nanoparticle
immune response
Sudan virus
mice
horse
purified IgG
long-lived plasma cells
antibodies
multivalency
virus-like particles
antigenic analysis
epitope characterization
hepatitis E vaccine
serological evaluation
virion-like epitopes
well-characterized vaccines
hepatitis B virus
surface (envelope) antigen
sub-viral particle
capsid
antigen display
platform
viral quantification
NTA
flow virometry
SRFM
cryo-TEM
SEM
plant virus
virus-like
vaccine platform
epitope
antigen
cat allergy
Fel d 1
HypoCat™
IL-13
interleukin-13
Tfh cells
cancer
immunotherapy
H7N9
pandemic influenza A
avian flu
IAV
VLP vaccine
n/a
thema EDItEUR::N History and Archaeology::NH History
thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBF Social and ethical issues
url ONIX_20210501_9783039430741_832