Nitro Compounds and Their Derivatives in Organic Synthesis
Nitro chemistry plays an important role in organic synthesis to construct new frameworks. This is due to the diverse properties of the nitro group. The strong electron-withdrawing ability of the nitro group reduces the electron density of the scaffold, facilitating reactions with nucleophiles or ele...
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| Dil: | İngilizce |
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MDPI - Multidisciplinary Digital Publishing Institute
2021
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| Online Erişim: | ONIX_20210501_9783039431489_841 |
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| collection | Directory of Open Access Books |
| description | Nitro chemistry plays an important role in organic synthesis to construct new frameworks. This is due to the diverse properties of the nitro group. The strong electron-withdrawing ability of the nitro group reduces the electron density of the scaffold, facilitating reactions with nucleophiles or electron transfer. In addition, the -hydrogen of the nitro group is highly acidic, giving a stable anion, which facilitates reactions with both electrophilic and nucleophilic reagents. In addition, the nitro group also serves as a good leaving group, which facilitates transformation to a wide variety of functional groups. Despite the substantial contributions of many researchers, nitro chemistry is still an exciting and challenging research area. This book brings together recent original research and review articles contributed by an international team of leading experts and pioneers in organic synthesis using nitro groups. It is sure to provide useful information and promising insights for researchers. |
| format | Online |
| id | doab-20.500.12854ir-69095 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-690952024-03-27T16:34:34Z Nitro Compounds and Their Derivatives in Organic Synthesis Nishiwaki, Nagatoshi nitro pyridone 1-methyl-2-quinolone cycloaddition direct functionalization perylenediimide nitro group organic materials Phenacylation of beta-nitropyridin-2-ones 8-nitro-5-RO-indolizines oxazole-pyrrole ring transformation conjugate addition dihydrofuran 1,3-dicarbonyl compound enolate isoxazoline N-oxide nitroketone nitronate nucleophilic substitution nitropyridines isoxazolo[4,3-b]pyridines 1,4-dihydropyridines nucleophilic addition Diels-Alder reaction dearomatization hexapyrrolohexaazacoronene nitration SNAr substitution ICT character aromaticity C–H functionalization total synthesis pyrrolidines anchimeric assistance epimerization PDE4 inhibitors 1,3-Dipole electron-withdrawing ability electrophilicity nucleophilicity thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general Nitro chemistry plays an important role in organic synthesis to construct new frameworks. This is due to the diverse properties of the nitro group. The strong electron-withdrawing ability of the nitro group reduces the electron density of the scaffold, facilitating reactions with nucleophiles or electron transfer. In addition, the -hydrogen of the nitro group is highly acidic, giving a stable anion, which facilitates reactions with both electrophilic and nucleophilic reagents. In addition, the nitro group also serves as a good leaving group, which facilitates transformation to a wide variety of functional groups. Despite the substantial contributions of many researchers, nitro chemistry is still an exciting and challenging research area. This book brings together recent original research and review articles contributed by an international team of leading experts and pioneers in organic synthesis using nitro groups. It is sure to provide useful information and promising insights for researchers. 2021-05-01T15:41:01Z 2021-05-01T15:41:01Z 2020 book ONIX_20210501_9783039431489_841 9783039431489 9783039431496 https://directory.doabooks.org/handle/20.500.12854/69095 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/2864 https://mdpi.com/books/pdfview/book/2864 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-03943-149-6 10.3390/books978-3-03943-149-6 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783039431489 9783039431496 120 Basel, Switzerland open access |
| spellingShingle | nitro pyridone 1-methyl-2-quinolone cycloaddition direct functionalization perylenediimide nitro group organic materials Phenacylation of beta-nitropyridin-2-ones 8-nitro-5-RO-indolizines oxazole-pyrrole ring transformation conjugate addition dihydrofuran 1,3-dicarbonyl compound enolate isoxazoline N-oxide nitroketone nitronate nucleophilic substitution nitropyridines isoxazolo[4,3-b]pyridines 1,4-dihydropyridines nucleophilic addition Diels-Alder reaction dearomatization hexapyrrolohexaazacoronene nitration SNAr substitution ICT character aromaticity C–H functionalization total synthesis pyrrolidines anchimeric assistance epimerization PDE4 inhibitors 1,3-Dipole electron-withdrawing ability electrophilicity nucleophilicity thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general Nitro Compounds and Their Derivatives in Organic Synthesis |
| title | Nitro Compounds and Their Derivatives in Organic Synthesis |
| title_full | Nitro Compounds and Their Derivatives in Organic Synthesis |
| title_fullStr | Nitro Compounds and Their Derivatives in Organic Synthesis |
| title_full_unstemmed | Nitro Compounds and Their Derivatives in Organic Synthesis |
| title_short | Nitro Compounds and Their Derivatives in Organic Synthesis |
| title_sort | nitro compounds and their derivatives in organic synthesis |
| topic | nitro pyridone 1-methyl-2-quinolone cycloaddition direct functionalization perylenediimide nitro group organic materials Phenacylation of beta-nitropyridin-2-ones 8-nitro-5-RO-indolizines oxazole-pyrrole ring transformation conjugate addition dihydrofuran 1,3-dicarbonyl compound enolate isoxazoline N-oxide nitroketone nitronate nucleophilic substitution nitropyridines isoxazolo[4,3-b]pyridines 1,4-dihydropyridines nucleophilic addition Diels-Alder reaction dearomatization hexapyrrolohexaazacoronene nitration SNAr substitution ICT character aromaticity C–H functionalization total synthesis pyrrolidines anchimeric assistance epimerization PDE4 inhibitors 1,3-Dipole electron-withdrawing ability electrophilicity nucleophilicity thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general |
| topic_facet | nitro pyridone 1-methyl-2-quinolone cycloaddition direct functionalization perylenediimide nitro group organic materials Phenacylation of beta-nitropyridin-2-ones 8-nitro-5-RO-indolizines oxazole-pyrrole ring transformation conjugate addition dihydrofuran 1,3-dicarbonyl compound enolate isoxazoline N-oxide nitroketone nitronate nucleophilic substitution nitropyridines isoxazolo[4,3-b]pyridines 1,4-dihydropyridines nucleophilic addition Diels-Alder reaction dearomatization hexapyrrolohexaazacoronene nitration SNAr substitution ICT character aromaticity C–H functionalization total synthesis pyrrolidines anchimeric assistance epimerization PDE4 inhibitors 1,3-Dipole electron-withdrawing ability electrophilicity nucleophilicity thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general |
| url | ONIX_20210501_9783039431489_841 |